Abstract: The present invention concerns methods for treating and preventing renal/kidney disease, insulin resistance/diabetes, fatty liver disease, and/or endothelial dysfunction/cardiovascular disease using synthetic triterpenoids, optionally in combination with a second treatment or prophylaxis.
Type:
Grant
Filed:
January 26, 2012
Date of Patent:
June 4, 2013
Assignees:
Reata Pharmaecuticals, Inc., Trustees of Dartmouth College
Inventors:
Michael B. Sporn, Karen T. Liby, Gordon W. Gribble, Tadashi Honda, Robert M. Kral, Colin J. Meyer