Patents Assigned to Recordati Industria Chimica e Farmacentica S.p.A.
  • Heterocyclylmethylidene derivatives and their use as modulators of mGluR5 receptors
    Patent number: 11440922
    Abstract: This invention relates to compounds of formula (I) and their use as allosteric modulators of mGluR5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for the treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction, such as schizophrenia or cognitive decline, dementia or cognitive impairment, or other pathologies that can be related directly or indirectly to glutamate dysfunction.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 13, 2022
    Assignee: Recordati Industria Chimica e Farmacentica S.p.A.
    Inventors: Carlo Riva, Davide Graziani, Matteo Longhi, Elisa Callegari, Fabio Frigerio, Patrizia Angelico