Patents Assigned to Recurium IP Holdings, LLC
  • Methods for cross coupling
    Patent number: 10793504
    Abstract: Methods of preparing substituted bicyclo[0.1.1.1]pentane compounds of Formula (I) comprise reacting a compound of Formula (A) with a compound of Formula (B) in the presence of a first transition metal catalyst selected from a palladium catalyst and a nickel catalyst, where the variables R1, R2, X1 and X2 are as described herein.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: October 6, 2020
    Assignee: Recurium IP Holdings, LLC
    Inventors: Joseph Robert Pinchman, Chad Daniel Hopkins, Kevin Duane Bunker, Peter Qinhua Huang
  • Analgesic compounds
    Patent number: 10653681
    Abstract: Disclosed herein are compounds of Formula (I), methods of synthesizing compounds of Formula (I), and methods of using compounds of Formula (I) as an analgesic.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: May 19, 2020
    Assignee: Recurium IP Holdings, LLC
    Inventors: Kevin Duane Bunker, Deborah Helen Slee, Chad Daniel Hopkins, Joseph Robert Pinchman, Mehmet Kahraman, Peter Qinhua Huang
  • Propellane derivates and synthesis
    Patent number: 10654812
    Abstract: Disclosed herein are compounds of the general Formula (I), and methods of synthesizing substituted bicyclo[1.1.1 jpentanes. The synthetic methods described herein use a [1.1.1]propellane, a Group VIII transition metal compound, a hydride source and a reagent that can contribute a substituent to form a substituted bicyclo[1.1.1]pentane, such as a compound of the general Formula (I).
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: May 19, 2020
    Assignee: Recurium IP Holdings LLC
    Inventor: Kevin Duane Bunker
  • Spirocyclic compounds
    Patent number: 10525036
    Abstract: Disclosed herein are spirocyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: January 7, 2020
    Assignee: Recurium IP Holdings, LLC
    Inventors: Peter Qinhua Huang, Mehmet Kahraman, Deborah Helen Slee, Kevin Duane Bunker, Chad Daniel Hopkins, Joseph Robert Pinchman, Sunny Abraham, Rakesh Kumar Sit, Daniel Lee Severance
  • EGFR inhibitor compounds
    Patent number: 10513509
    Abstract: Disclosed herein are nitrogen-containing bicyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: December 24, 2019
    Assignee: Recurium IP Holdings, LLC
    Inventors: Kevin Duane Bunker, Peter Qinhua Huang, Sunny Abraham, Joseph Robert Pinchman, Chad Daniel Hopkins, Deborah Helen Slee
  • Spirocyclic compounds
    Patent number: 10493060
    Abstract: Disclosed herein are spirocyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 3, 2019
    Assignee: Recurium IP Holdings, LLC
    Inventors: Peter Qinhua Huang, Mehmet Kahraman, Deborah Helen Slee, Kevin Duane Bunker, Chad Daniel Hopkins, Joseph Robert Pinchman, Sunny Abraham, Rakesh Kumar Sit, Daniel Lee Severance