Abstract: A drain tube holder system for securely retaining drainage tubes and reservoir bulbs against the body without impeding movement of the wearer. The drain tube holder system generally includes a strap adapted to be secured around various portions of an individual's body such as the waist, thigh, or shoulder. A retainer attachment is fixedly or removably secured to the strap. The retainer attachment includes one or more pouches adapted to retain one or more tubes and bulbs therein, with a first end of the tube exiting the body of the individual before being secured within a tube retainer within the pouch. The pouch is also adapted to securely retain a bulb, such as a reservoir, adapted to retain fluids drained through the tube. Using the present invention, an individual may enjoy improved comfort while wearing a drainage tube, such as after a medical procedure.