Abstract: Novel ?-aryl-?-oxysubstituted alkylcarboxylic acids of the formula (I) and compositions containing them. The compounds have hypolipidemic, antihyperglycemic uses.
Type:
Grant
Filed:
July 14, 2005
Date of Patent:
October 10, 2006
Assignees:
Dr. Reddy's Research Foundation, Reddy-Cheminor, Inc.
Abstract: The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel &bgr;-aryl-&agr;-oxysubstituted alkylcarboxylic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereosomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
Type:
Grant
Filed:
March 27, 2001
Date of Patent:
December 16, 2003
Assignees:
Dr. Reddy's Laboratories Limited, Reddy-Cheminor Inc.
Abstract: The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
Type:
Application
Filed:
December 26, 2001
Publication date:
September 5, 2002
Applicant:
DR. REDDY'S RESEARCH FOUNDATION & REDDY-CHEMINOR, INC.
Abstract: The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel &bgr;-aryl-&agr;-oxysubstituted alkylcarboxylic acids of the general formula (I),
their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
Type:
Grant
Filed:
February 18, 2000
Date of Patent:
September 3, 2002
Assignees:
Dr. Reddy's Research Foundation, Reddy Cheminor, Inc.
Abstract: A compound of formula (1)
it derivatives, its analogs, its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts, or its pharmaceutically acceptable solvates, processes for its preparation and methods of use thereof.
Type:
Grant
Filed:
February 24, 1999
Date of Patent:
August 27, 2002
Assignees:
Dr. Reddy's Research Foundation, Reddy-Cheminor, Inc.
Abstract: The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
Type:
Application
Filed:
January 8, 2002
Publication date:
August 1, 2002
Applicant:
DR. REDDY'S RESEARCH FOUNDATION & REDDY-CHEMINOR, INC.
Abstract: The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them This invention particularly relates to novel azolidinedione derivatives of the general formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them
Type:
Grant
Filed:
April 5, 2001
Date of Patent:
April 16, 2002
Assignees:
Dr. Reddy's Research Foundation, Reddy-Cheminor, Inc.
Abstract: The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel &bgr;-aryl-&agr;-oxysubstituted alkylcarboxylic acids of the general formula (I),
their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
Type:
Grant
Filed:
February 18, 2000
Date of Patent:
April 9, 2002
Assignees:
Dr. Reddy's Research Foundation, Reddy-Cheminor Inc.
Abstract: The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their analogues, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
Type:
Grant
Filed:
December 2, 1997
Date of Patent:
November 6, 2001
Assignees:
Reddy-Cheminor, Inc., Dr. Reddy's research foundation
Abstract: The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel azolidinedione derivatives of the general formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them.
Type:
Grant
Filed:
March 24, 2000
Date of Patent:
October 30, 2001
Assignees:
Dr. Reddy's Research Foundation, Reddy-Cheminor Inc.
Abstract: The present invention relates to novel antidiabetic compounds, their tautomeric forms, their derivatives, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel azolidinedione derivatives of the general formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them.
Type:
Application
Filed:
April 5, 2001
Publication date:
October 18, 2001
Applicant:
DR. REDDY'S RESEARCH FOUNDATION & REDDY- CHEMINOR, INC.
Abstract: The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel &bgr;-aryl-&agr;-oxysubstituted alkylcarboxylic acids of the general formula (1), their derivatives, their analogs, their tautomeric forms, their stereosomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
Type:
Application
Filed:
March 27, 2001
Publication date:
October 4, 2001
Applicant:
DR. REDDY'S RESEARCH FOUNDATION & REDDY-CHEMINOR INC.
Abstract: Compounds of formula (I)
its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts or its pharmaceutically acceptable solvates can be used to prevent or treat diabetes caused by insulin resistance or impaired glucose tolerance or complications of diabetes caused by insulin resistance or impaired glucose tolerance. The compounds can also be used to reduce cholesterol, body weight, blood glucose, triglycerides and free fatty acids in the blood.
Type:
Grant
Filed:
May 27, 1998
Date of Patent:
July 24, 2001
Assignees:
Reddy-Cheminor, Inc., Dr. Reddy's Research Foundation
Abstract: Novel water soluble C-ring analogues of 20(S)-camptothecin having the general formula 1.
All the compounds of the formula 1 are prepared from the compounds of the general formula 2 having 20(S)-chiral carbon. The compounds of the formula 1 possess potent anti-cancer and anti-viral properties. The invention also provides an alternate process for the preparation of known C-5 substituted compounds of the formula 1.
Type:
Grant
Filed:
December 19, 1996
Date of Patent:
April 10, 2001
Assignees:
Dr. Reddy's Research Foundation, Reddy Cheminor, Inc.
Abstract: Novel water soluble C-ring analogues of 20(S)-camptothecin having the general formula 1,
All the compounds of the formula 1 are prepared from the compounds of the general formula 2 having 20(S)-chiral carbon where R1 to R5 have the meaning given above. The compounds of the formula 1 possess potent anti-cancer and anti-viral properties.
Type:
Grant
Filed:
December 19, 1996
Date of Patent:
January 23, 2001
Assignees:
Reddy's Research Foundation, Reddy-Cheminor, Inc.
Inventors:
Subrahmanyam Duvvuri, Venkateswarlu Akella, Sharma Manohara Vedula, Sastry V. R. S. Thungathurthi, Vamsee Krishna Chintakunta, Shobha Madabhushi
Abstract: A compound of formula (I) ##STR1## its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts or its pharmaceutically acceptable solvates, wherein R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are the same or different; R.sup.1 and R.sup.2 together represent along with carbon atoms to which they are attached an aromatic cyclic structure containing 5-6 ring atoms which may optionally be substituted; X represents a heteroatom selected from oxygen or sulfur; R.sup.7 represents hydrogen atom, hydroxy, alkoxy, halogen, lower alkyl group or optionally substituted aralkyl group or forms a bond together with R.sup.8 ; R.sup.8 represents hydrogen atom, hydroxy, alkoxy, halogen, lower alkyl group or optionally substituted aralkyl or R.sup.8 forms a bond together with R.sup.
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
December 12, 2000
Assignees:
Reddy-Cheminor Inc., Dr. Reddy's Research Foundation