Abstract: Processes for preparing azacitidine. Further included are processes for the preparation of crystalline azacitidine crystalline Form I and mixtures of azacitidine crystalline Forms I and II.
Type:
Application
Filed:
February 6, 2014
Publication date:
June 5, 2014
Applicants:
DR. REDDY'S LABORATORIES INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Aspects of the present appliction relate to pharmaceutical formulations comprising bendamustine or its pharmaceutically acceptable salts, isomers, racemates, enantiomers, hydrates, solvates, metabolites, polymorphs, and mixtures therof, suitable for phamaceutical use. Aspects further provide methods of producing stable bendamustine compositions.
Type:
Application
Filed:
January 25, 2012
Publication date:
May 22, 2014
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
Type:
Application
Filed:
October 14, 2013
Publication date:
May 15, 2014
Applicant:
DR. REDDY'S LABORATORIES LTD.
Inventors:
Anima BARUAH, Dibyendu DE, Ish Kumar KHANNA, Sivaram PILLARISETTI, Santanu MAITRA, Christopher W. ALEXANDER, Jennepalli SREENU, Indu Dagar, Shanavas Alikunju
Abstract: Processes for preparing azacitidine. Further included are processes for the preparation of crystalline azacitidine crystalline Form I and mixtures of azacitidine crystalline Forms I and II.
Type:
Grant
Filed:
January 28, 2011
Date of Patent:
April 22, 2014
Assignees:
Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc.
Abstract: The present application discloses stable pharmaceutical compositions for the oral administration of febuxostat with pharmaceutical excipients which provide improved dissolution rate and polymorphic stability both while manufacturing and during storage and process for preparing the stable compositions, packaging and their use in the treatment of gout of hyperuricemia.
Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
Type:
Grant
Filed:
June 28, 2006
Date of Patent:
December 10, 2013
Assignee:
Dr. Reddy's Laboratories Ltd.
Inventors:
Anima Baruah, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher W. Alexander, Jennepalli Sreenu, Indu Dagar, Shanavas Alikunju
Abstract: The present invention relates to an oral pharmaceutical composition comprising metronidazole, wherein metronidazole is released from the composition generally at the pH 5.0 and above.
Abstract: The present application relate to amorphous form of Apixaban useful in making pharmaceutically acceptable dosage forms, and to processes for their preparation.
Type:
Application
Filed:
March 13, 2013
Publication date:
September 19, 2013
Applicant:
DR. REDDY'S LABORATORIES LTD.
Inventors:
Subba Reddy Peddi Reddy, Md Arshad Alam
Abstract: The present invention relates to stable pharmaceutical compositions comprising fesoterodine or a pharmaceutically acceptable salt thereof. In particular, the invention relates to pharmaceutical compositions of fesoterodine or a pharmaceutically acceptable salt thereof and a stabilizer. The invention also relates to processes for making such compositions and the methods of using such compositions.
Abstract: Methods of producing compositions of trans-4-amino-2-cyclopentene-1-carboxylic acid derivatives are described. Also described is an amine salt of a compound having formula A, having components present in both cis and trans structures.
Type:
Grant
Filed:
January 2, 2012
Date of Patent:
September 3, 2013
Assignees:
Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Ltd.
Inventors:
Richard Lloyd, Justine Ann Peterson, Mark Jackson
Abstract: Aspects of the present disclosure include crystalline bazedoxifene free base, crystalline bazedoxifene acetate Form D, and processes for their preparation. The drug compound having the adopted name “bazedoxifene acetate” has a chemical name 1-[4-(2-azepan-1-yl-ethoxy)benzyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetic acid, and has the chemical structure shown below as Formula I.
Type:
Application
Filed:
September 14, 2011
Publication date:
August 29, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Aspects of the present application relate to a microcrystalline monoclinic form of asenapine maleate represented by structural Formula (I); processes for its preparation; and pharmaceutically acceptable dosage forms thereof.
Type:
Application
Filed:
June 16, 2011
Publication date:
August 15, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Aspects of the present application relate to molecular weight markers of glatiramer acetate for accurate determination of the average molecular weight of glatiramer acetate.
Type:
Application
Filed:
July 28, 2011
Publication date:
August 15, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: The application describes methods to enhance protein production using mammalian cells. Increased production of heterologous protein can be obtained by increasing osmolality and lowering temperature. The method maintains the cell growth rate and provides high product yield.
Type:
Application
Filed:
January 6, 2011
Publication date:
August 15, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Makkapati Satakarni, S. Nikam Vaibhav, Subrahmanyam Satyam
Abstract: The present application relates to process for the preparation of imatinib mesylate. This application also relates to the processes for preparation of alpha crystalline form of imatinib mesylate.
Type:
Application
Filed:
July 28, 2011
Publication date:
August 8, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: A process comprising: (a) reduction of N-acetyl-3-aminopyridine (2): or its salt in the presence of hydrogen and a palladium catalyst deposited on solid support; (b) converting racemic N-acetyl-3-aminopiperidine (3) or its salt produced in step (a) to rac-3-aminopiperidine (rac-4) or its salt; (c) resolution of the racemic 3-aminopiperidine (rac-4) or its salt produced in step (b) with a chiral acid.
Type:
Application
Filed:
June 17, 2011
Publication date:
July 4, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Graham Andrew Meek, Syam Kumar Unniaran Purakkal Kunhimon, R Shankar, Vilas Hareshwar Dahanukar, TH. Krishna Mohan, Manoj Balu Wagh, Abir Kumar Pal, V. Madhu Babu Meesala, Sonmit Shrivastava