Abstract: An object of the present invention is to provide a process for conveniently and efficiently producing high purity thioredoxin from yeast. In the production of thioredoxin using yeast, thioredoxin is produced through the following steps (i) to (iii): (1) culturing the yeast; (2) stressing the yeast obtained in step (1) to cause a release of thioredoxin from a cell of the yeast; and (3) collecting the thioredoxin released from the yeast cell.

Abstract: The object of the invention is to provide animal model of disorder and method of screening an agent for preventing or treating Metabolic Syndrome by using the animal model, wherein said animal model is used as experimental material which is essential to detailed analysis of component and pathologic condition of Metabolic Syndrome and to development of the method for treating and the agent for preventing and treating the Metabolic Syndrome. The above object is achieved by the non-human mammal model of disorders, whose TBP-2 gene is functionally deficient on chromosome, wherein the disorders are caused by impaired fatty acid utilization, and a method of screening an agent for preventing or treating Metabolic syndrome comprising; administering a test article to the non-human mammal whose TBP-2 gene is functionally deficient on chromosome.

Abstract: The binding specificity of at least one plasma protein suspended or dissolved in a liquid medium is altered by exposing the protein to an oxidizing agent or an electric current sufficient to alter its binding specificity. A masked protein such as an autoantibody can be recovered from blood or blood products or extracts by oxidizing the protein to change its binding specificity.

Abstract: The object of the invention is to provide animal model of disorder and method of screening an agent for preventing or treating Metabolic Syndrome by using the animal model, wherein said animal model is used as experimental material which is essential to detailed analysis of component and pathologic condition of Metabolic Syndrome and to development of the method for treating and the agent for preventing and treating the Metabolic Syndrome. The above object is achieved by the non-human mammal model of disorders, whose TBP-2 gene is functionally deficient on chromosome, wherein the disorders are caused by impaired fatty acid utilization, and a method of screening an agent for preventing or treating Metabolic syndrome comprising; administering a test article to the non-human mammal whose TBP-2 gene is functionally deficient on chromosome.

Abstract: The present invention provides a therapeutic agent for treating inflammatory bowel diseases comprising as an active ingredient at least one member selected from polypeptides belonging a family exhibiting thioredoxin activity.

Abstract: Preventive or therapeutic agents for controlling various disorders induced by toxic substances in smoke produced by the combustion of fibers such as tobacco are disclosed. A polypeptide of the thioredoxin family (TRX) prevents toxic substances in smoke, produced by the combustion of fibers such as tobacco, from inducing inflammatory reactions and tissue fibrosis. Accordingly, TRX is effective for controlling of a wide range of disorders caused by toxic substances contained in smoke produced by combustion of fibers. The object of the present invention is to provide the preventive or therapeutic agents for disorders caused by toxic substances contained in smoke produced by combustion of fibers comprising an effective amount of polypeptide of thioredoxin family and/or one or more of its inducers.

Abstract: The invention provides compositions and methods for inhibiting nematode damage to plants. The compositions comprise acid extracts or alcohol extracts from jugloneproducing members of the Juglandaceae. The methods comprise applying the compositions of the invention to soil contacting roots of nematode-susceptible plants.

Abstract: Methods to reduce hexavalent chromium (Cr(VI)) in chromite processing wastes include one or more of the following steps: contacting the chromite processing wastes with an oxygen scavenger or chemical reducer; permitting the chromite processing wastes to react with the oxygen scavenger or chemical reducer; contacting the chromite processing wastes with ferrous ion; contacting the chromite processing wastes with sulfide ion; and, contacting the chromite processing wastes with ferrous sulfide.

Abstract: A method for the therapeutic and prophylactic treatment of subjects infected with the papilloma virus. More specifically, a method of therapeutic treatment of a papilloma virus in a subject by administering an anti-papilloma virus effective amount of CTC-96 to the subject. In addition, a method of prophylactic treatment against a papilloma virus in a subject by administering an anti-papilloma virus effective amount of CTC-96 to the subject to minimize the likelihood of the subject being infected by the papolloma virus.

Abstract: This invention provides novel methods for improving plant quality and yield in the presence of pathogens. The method increases the levels of pathogenesis-related proteins, such as PR1, phenylalanine ammonia lyase, or plant cell wall proteins such as hydroxyproline-rich glycoproteins, in a plant by contacting the plant with a plant systemic inducer and a reactive oxygen species wherein the amount of the reactive oxygen species is sufficient to increase the amount of the pathogenesis-related protein above the level induced by the plant systemic inducer in the absence of the reactive oxygen species. A preferred reactive oxygen species is peracetic acid; a preferred plant systemic inducer is salicylic acid.

Abstract: This invention provides novel methods for improving plant quality and yield in the presence of pathogens. The method increases the levels of pathogenesis-related proteins, such as PR1, phenylalanine ammonia lyase, or plant cell wall proteins such as hydroxyproline-rich glycoproteins, in a plant by contacting the plant with a plant systemic inducer and a reactive oxygen species wherein the amount of the reactive oxygen species is sufficient to increase the amount of the pathogenesis-related protein above the level induced by the plant systemic inducer in the absence of the reactive oxygen species. A preferred reactive oxygen species is peracetic acid; a preferred plant systemic inducer is salicylic acid.

Abstract: A process is disclosed for the preparation of a dialkyl peroxide comprising reacting one or more members selected from the group consisting of an alkylating alcohol of the formula ROH, and an olefin of the formula (R2)(R2a)C?C(R3)(R3a), wherein R is C1–C10 allyl, and R2, R2a, R3, and R3a are independently selected from hydrogen and C1–C10 alkyl; with a hydroperoxide of the formula R1OOH, wherein R1 is C1–C10 allyl; in the presence of an effective amount of a substantially solid, insoluble, heterogenous acidic catalyst; followed by separation of the reaction mixture from said catalyst; wherein said catalyst has readily available acidity for organic reactions and exists in the solid phase in the processes of the invention, while the reactants in those processes, by contrast, exist in the liquid and/or gaseous phase, whence the catalyst is referred to as heterogeneous.

Abstract: The present invention relates to a water purifying device including: a cell unit consisting of a high purity ceramic for obtaining far infrared ray, and having a shape according to a kind of water tank, a ring-shaped Volta cell consisting of a non-ferrous metal being provided in the cell unit; and a lump unit being connected to the cell unit through a metal coil, and consisting of ceramic, a conductive lump consisting of a non-ferrous metal being provided in the lump unit. Accordingly, the water purifying device is easily installed in the water tank, for disinfecting bacteria, restricting generation of bacteria, removing odor, and facilitating growth of aquatic plants and fishes. As a result, a number of changing water in the water tank can be considerably reduced, to improve efficiency.

Abstract: This invention provides novel methods for improving plant quality and yield in the presence of pathogens. The method increases the levels of pathogenesis-related proteins, such as PR1, phenylalanine ammonia lyase, or plant cell wall proteins such as hydroxyproline-rich glycoproteins, in a plant by contacting the plant with a plant systemic inducer and a reactive oxygen species wherein the amount of the reactive oxygen species is sufficient to increase the amount of the pathogenesis-related protein above the level induced by the plant systemic inducer in the absence of the reactive oxygen species. A preferred reactive oxygen species is peracetic acid; a preferred plant systemic inducer is salicylic acid.

Abstract: There is disclosed a battery system to be used in downhole application. The battery system provides energy to operate the measurement devices associated with drilling. The system includes a plurality of cells, each comprising an electrically insulating mandrel which is shaped to fit over an inner tube, and a combination of an anode, a cathode and a solid polymer electrolyte, all disposed over the mandrel. The individual cells are mounted end to end and are interlocked together to prevent rotation of the cells relative to one another. The cells are electrically connected together and they are all mounted between an inner and an outer tube.

Abstract: A method of treating an animal having a condition associated with the presence of cyanide in quantities sufficient to cause undesirable symptoms which comprises administering to the subject a compound in an amount effective to alleviate the undesirable symptoms, the compound having the structure: ##STR1## wherein R.sup.1 and R.sup.1' are the same or different and each is an alkyl group, a phenyl group or a substituted derivative of a phenyl group;R.sup.2 and R.sup.2' are the same or different and each is hydrogen, an unbranched alkyl group, a halide or a group having the structure R--C-- ##STR2## wherein R is hydrogen, an alkoxide group, and alkyl group or OH; R.sup.3 and R.sup.3' are the same or different and each is hydrogen or an alkyl group;X and X' are the same or different and each is a water-soluble group having weak to intermediate field strength; andQ.sup.- is a soluble, pharmaceutically acceptable negative ion.

Abstract: A method of treating a subject having a condition associated with the presence of cyanide in quantities sufficient to cause undesirable symptoms which comprises administering to the subject a compound in an amount effective to alleviate the undesirable symptoms, the compound having the structure: ##STR1## wherein R.sup.1 and R.sup.1' are the same or different and each is an alkyl group, a phenyl group or a substituted derivative of a phenyl group;R.sup.2 and R.sup.2' are the same or different and each is hydrogen, an unbranched alkyl group, a halide or a group having the structure ##STR2## wherein R is hydrogen, an alkoxide group, and alkyl group or OH; R.sup.3 and R.sup.3' are the same or different and each is hydrogen or an alkyl group;X and X' are the same or different and each is a water-soluble group having weak to intermediate field strength; andQ.sup.-- is a soluble, pharmaceutically acceptable negative ion.

Abstract: The present invention relates to a process for the treatment of waste gas discharged from a cyclohexane oxidation reactor used in the manufacture of adipic acid, said waste gas containing mainly nitrogen, oxygen, carbon monoxide, carbon dioxide, acetic acid, and up to 10% by weight cyclohexane, as well as other gases or vapors, by (a) scrubbing the waste gas from the cyclohexane oxidation reactor with acetic acid in a first absorption step to reduce the amount of cyclohexane to a residual content of less than about 1% by weight, (b) scrubbing the waste gas from the first absorption step with water in a second absorption step to reduce the amount of acetic acid to a residual content of less than about 1% by weight, and (c) subjecting the scrubbed waste gas from the second absorption step to an oxidation step to oxidize carbon monoxide and other oxidizable components of the waste gas to carbon dioxide and water.

Abstract: The invention relates to a process for the oxidative preparation of C.sub.5 -C.sub.8 aliphatic dibasic acids by(1) reacting(a) at least one saturated cycloaliphatic hydrocarbon having from 5 to 8 ring carbon atoms in the liquid phase and(b) an excess of an oxygen-containing gas in the presence of(c) a solvent comprising an organic acid containing only primary and/or secondary hydrogen atoms and(d) at least about 0.002 mole per 1000 grams of reaction mixture of a polyvalent heavy metal catalyst;(2) removing the aliphatic dibasic acid; and(3) recycling intermediates, post-oxidation components, and derivatives thereof remaining after removal of the aliphatic dibasic acid into the oxidation reaction.

Abstract: The present invention relates to a process for the preparation of C.sub.5 -C.sub.8 aliphatic dibasic acids through oxidation of corresponding saturated cycloaliphatic hydrocarbons by(1) reacting, at a cycloaliphatic hydrocarbon conversion level of between about 7% and about 30%,(a) at least one saturated cycloaliphatic hydrocarbon having from 5 to 8 ring carbon atoms in the liquid phase and(b) an excess of oxygen gas or an oxygen-containing gas mixturein the presence of(c) less than 1.5 moles of a solvent per mole of cycloaliphatic hydrocarbon (a), wherein said solvent comprises an organic acid containing only primary and/or secondary hydrogen atoms and(d) at least about 0.002 mole per 1000 grams of reaction mixture of a polyvalent heavy metal catalyst; and(2) isolating the C.sub.5 -C.sub.8 aliphatic dibasic acid.