Patents Assigned to Redox Bioscience Inc.
  • Process for producing thioredoxin by stressing yeast cells
    Patent number: 8450099
    Abstract: An object of the present invention is to provide a process for conveniently and efficiently producing high purity thioredoxin from yeast. In the production of thioredoxin using yeast, thioredoxin is produced through the following steps (i) to (iii): (1) culturing the yeast; (2) stressing the yeast obtained in step (1) to cause a release of thioredoxin from a cell of the yeast; and (3) collecting the thioredoxin released from the yeast cell.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: May 28, 2013
    Assignees: Kyoto University, Redox Bioscience Inc., Kizakura Co., Ltd.
    Inventors: Junji Yodoi, Yoshiharu Inoue, Shingo Izawa, Hiroshi Masutani, Kazuo Murata, Shogo Tamasu
  • Method of screening for a substance that strengthens a bond between thioredoxin and macrophage migration inhibition factor
    Patent number: 8440413
    Abstract: Disclosed is a screening method which can select a substance having an influence on the binding between thioredoxin and MIF.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: May 14, 2013
    Assignee: Redox Bioscience, Inc.
    Inventors: Junji Yodoi, Norihiko Kondo, Aoi Son, Noriko Kato, Tomijiro Hara, Tomohisa Horibe
  • Agent for treatment of inflammatory bowel disease
    Patent number: 7312189
    Abstract: The present invention provides a therapeutic agent for treating inflammatory bowel diseases comprising as an active ingredient at least one member selected from polypeptides belonging a family exhibiting thioredoxin activity.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: December 25, 2007
    Assignee: Redox Bioscience Inc.
    Inventors: Hiroyuki Tamaki, Hajime Nakamura, Junji Yodoi, Kazuichi Okazaki, Akiyoshi Nishio, Tsutomu Chiba
  • Preparation for preventing or treating disorders caused by toxic constituents contained in fiber combustion smoke
    Publication number: 20070264248
    Abstract: Preventive or therapeutic agents for controlling various disorders induced by toxic substances in smoke produced by the combustion of fibers such as tobacco are disclosed. A polypeptide of the thioredoxin family (TRX) prevents toxic substances in smoke, produced by the combustion of fibers such as tobacco, from inducing inflammatory reactions and tissue fibrosis. Accordingly, TRX is effective for controlling of a wide range of disorders caused by toxic substances contained in smoke produced by combustion of fibers. The object of the present invention is to provide the preventive or therapeutic agents for disorders caused by toxic substances contained in smoke produced by combustion of fibers comprising an effective amount of polypeptide of thioredoxin family and/or one or more of its inducers.
    Type: Application
    Filed: May 23, 2006
    Publication date: November 15, 2007
    Applicant: Redox Bioscience Inc.
    Inventors: Junji Yodoi, Michiaki Mishima, Yuma Hoshino, Hajime Nakamura, Tomijiro Hara, Makiko Narita