Patents Assigned to REFLOW MEDICAL, INC.
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Patent number: 11877762Abstract: A retrieval device can include inwardly facing protruding features that facilitate engagement and capture of a thrombus or other mass from a body lumen of a patient. The protruding features can deploy from a frame of the retrieval device to extend radially inwardly toward an opposing side of the frame. When deployed into a thrombus, the protruding features engage and urge the thrombus as the retrieval device moves to facilitate capture.Type: GrantFiled: October 30, 2020Date of Patent: January 23, 2024Assignee: REFLOW MEDICAL, INC.Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, Jr., Patrick Lo
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Patent number: 11648139Abstract: Delivery systems for expandable elements, such as stents or scaffolds having spikes, flails, or other protruding features for penetrating target tissue and/or delivering drugs within a human patient are described along with associated methods for using such systems. The delivery systems can be provided with a stent that is positioned over an inflatable balloon for expansion and delivery of the stent to a target delivery location. By positioning the stent over and about the inflatable balloon, the stent is ready to be expanded by the balloon immediately upon unsheathing with respect to the outer shaft. Additionally or alternatively, a stent can be positioned in an axially offset arrangement with respect to a balloon to reduce the need for space required by overlapping components.Type: GrantFiled: October 4, 2019Date of Patent: May 16, 2023Assignee: REFLOW MEDICAL, INC.Inventors: Teodoro S. Jimenez, Jr., Patrick Lo, John Fulkerson, Isa Rizk, Francisco Aguayo, Jihad Ali Mustapha, Gary Ansel
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Patent number: 11565079Abstract: A delivery device can be provided with a low outer profile and high flexibility for navigating tortuous anatomy. An inner lumen defined by a shaft of the delivery device provides adequate space for delivery devices to target anatomy. Additionally, the delivery device maintains the patency of its lumen even when positioned within tortuous anatomy. The turns of filar(s) forming a coil of the shaft adjust their axial spacing relative to each other to avoiding buckling that would otherwise result in a narrowing of the inner lumen.Type: GrantFiled: August 13, 2020Date of Patent: January 31, 2023Assignee: REFLOW MEDICAL, INC.Inventors: Outhit Bouasaysy, Isa Rizk, John Fulkerson
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Patent number: 11504142Abstract: A delivery system can be provided with an ability to change its configurations to achieve both access to target anatomy and treatment thereof. Such treatments can include directing interventional devices around an occlusion. By providing different functionality at different stages, the need to exchange and replace tools at different stages can be reduced or eliminated. Accordingly, such operations can be completed more rapidly, efficiently, and safely.Type: GrantFiled: August 13, 2020Date of Patent: November 22, 2022Assignee: ReFlow Medical, Inc.Inventors: Outhit Bouasaysy, John Fulkerson, Isa Rizk, Fadi Saab
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Patent number: 11253379Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: GrantFiled: March 6, 2019Date of Patent: February 22, 2022Assignee: ReFlow Medical, Inc.Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, Jr.
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Patent number: 10799255Abstract: Methods for treating a patient using intravascular devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to an intravascular device having an elongated member coupled to and extending between a handle and an angled distal portion. The distal portion is moveable between a first configuration having a first shape configured for intravascular delivery and a second configuration having a second shape, different than the first shape, that is configured for intravascular delivery.Type: GrantFiled: August 27, 2014Date of Patent: October 13, 2020Assignee: REFLOW MEDICAL, INC.Inventors: Isa Rizk, John Fulkerson, Mahmood Razavi
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Patent number: 10258487Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: GrantFiled: March 27, 2017Date of Patent: April 16, 2019Assignee: REFLOW MEDICAL, INC.Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, Jr.
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Patent number: 10172729Abstract: Expandable elements having drug-delivery features and associated systems and methods are disclosed herein. In one embodiment, a drug-eluting stent includes a radially expandable cylindrical frame having a plurality of struts. The frame is transformable between a low-profile delivery state and an expanded deployed state. A plurality of drug-delivery features are carried by one of the struts and configured to deliver a drug to a treatment site within the patient or piercing through the tissue wall to break the constricting of the vessel wall inwardly. When the frame is in the expanded state within a body lumen of the patient, the drug-delivery features extend radially outwardly away from the strut and are configured to engage and, in some arrangements, pass through a wall of the body lumen.Type: GrantFiled: October 12, 2016Date of Patent: January 8, 2019Assignee: REFLOW MEDICAL, INC.Inventors: John Fulkerson, Isa Rizk, Jihad Ali Mustapha, Teodoro S. Jimenez, Jr.
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Patent number: 9204893Abstract: Ablation, crossing, and cutting systems, devices and associated methods, including a crossing device, comprising, in combination: a spring-enhanced handle and body configured to controllably extend and retract a blade within a microcatheter for addressing an occlusion within a vessel of a patient to provide improved access for supplemental treatment and reperfusion.Type: GrantFiled: September 30, 2009Date of Patent: December 8, 2015Assignee: ReFlow Medical, Inc.Inventors: Isa Rizk, John Fulkerson
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Publication number: 20130035750Abstract: Ablation, crossing, and cutting systems, devices and associated methods, including a crossing device, comprising, in combination: a spring-enhanced handle and body configured to controllably extend and retract a blade within a microcatheter for addressing an occlusion within a vessel of a patient to provide improved access for supplemental treatment and reperfusion.Type: ApplicationFiled: October 9, 2012Publication date: February 7, 2013Applicant: REFLOW MEDICAL, INC.Inventor: ReFlow Medical, Inc.