Patents Assigned to REFORM BIOLOGIES, LLC
  • Stabilizing excipients for therapeutic protein formulations
    Patent number: 10610600
    Abstract: The invention encompasses therapeutic formulations comprising a protein active ingredient and a stabilizing excipient, methods of improving stability in a therapeutic formulation comprising a protein active ingredient by adding a stability-improving amount of a stabilizing excipient to the therapeutic formulation, and methods of reducing adverse infusion-related effects in a patient, comprising administering to a patient in need thereof a therapeutic formulation comprising a protein active ingredient and a stabilizing excipient.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: April 7, 2020
    Assignee: REFORM BIOLOGIES, LLC
    Inventors: David S. Soane, Robert P. Mahoney, Philip Wuthrich, Daniel G. Greene