Abstract: Polypeptides which stimulate bone growth: Gly Ile Gly Lys Arg Thr Asn Glu His Thr Ala Asp Cys Lys Ile Lys Pro Asn Thr Leu His Lys Lys Ala Ala Glu Thr Leu Met Val Leu Asp Gln Asn Gln Pro (SEQ ID NO:1) and subsequences, particularly Arg Thr Asn Glu His Thr Ala Asp Cys Lys (SEQ ID NO:9) and associated nucleotide sequences, methods of preparation and use, antibodies and kits.

Abstract: A polypepide substance isolated from rat serum which, upon administration to rats incapable of producing PTH (parathyroidectomized rats), produces an increase in the observed bone mineral apposition rate. The substance bas been isolated in two forms, a first larger polypeptide having a molecular weight about twice that of a second smaller polypeptide. The first eleven amino acids of the sequence of the smaller polypepeptide have been determined to be Gly Pro Gly Gly Ala Gly Glu Thr Lys Pro Ile (SEQ ID NO:3). The first seven amino acids of the larger polypeptide have been determined to be Gly Pro Gly Gly Ala Gly Glu (SEQ ID NO:2). The larger polypeptide might be the dimer of the smaller peptide. A nucleic acid probe, based on the amino acid sequence of the rat peptide was used to screen a human liver cDNA fetal library.

Abstract: The present invention provides improved osteogenic compositions having enhanced by the sorption of growth factors, of nutrient factors, or drugs onto or into the compositions. Compositions may consist of collagen and demineralized bone materials onto and into which growth factors, antimicrobial agent, a nutrient factors, or other soluble factors may be sorbed to enhance the osteogenic factor. These materials can be used in a wide range of clinical procedures to replace and restore osseous or periodontal defects.

Abstract: A system and method for generating bio-active frequencies. Such generated frequencies are very precise and are accurate within 0.001 Hz. The frequencies are used to advantage in health science applications such as killing microorganisms and viruses and enhancing tissue regeneration and may be used in various commercial and industrial applications, such as food processing. A specific precise frequency synthesizer is controlled by a programmable control that instructs the synthesizer to generate a specific precise frequency or a series of precise frequencies. A keyboard is actuable by a user to select a specific frequency or sequence of frequencies or a preprogrammed series of frequencies. Depending upon the specific frequency being generated, a circuit gates the generated signal ON or OFF with a predetermined determinable periods being selected for such ON/OFF periods.

Abstract: A system and method for generating bio-active frequencies. Such generated frequencies are very precise and are accurate within 0.001 Hz. The frequencies are used to advantage in health science applications such as killing microorganisms and viruses and enhancing tissue regeneration and may be used in various commercial and industrial applications, such as food processing. A specific precise frequency synthesizer is controlled by a programmable control that instructs the synthesizer to generate a specific precise frequency or a series of precise frequencies. A keyboard is actuable by a user to select a specific frequency or sequence of frequencies or a preprogrammed series of frequencies. Depending upon the specific frequency being generated, a circuit gates the generated signal ON or OFF with a predetermined determinable periods being selected for such ON/OFF periods.

Abstract: An electrolytic filter system (16) is disclosed for use in treating fluid provided by a fluid source(12) to a supplied environment (14). The system includes an electrolytic cell(18) controlled by control circuit(20). Various alternative constructions of the cell are described in which the effective separation of active electrodes, as well as the effective area of the active electrodes can be altered by a switching circuit (94) and controller (96) included in the control circuit (20). The controller responds to inputs from a current sensor (92) reflecting variations in the resistivity of the water. As a result, the controller is able to alter the effective separation and area of the active electrode, in response to resistivity variations to provide optimal operation.

Abstract: A fluid system (10) is disclosed including a filter system (16) for the moving contaminants from fluid provided by a fluid source (12) to a supplied environment (14). The filter system includes an electrolytic or electrostatic cell (26) which is operated by a control circuit (28). The control circuit is programmed to continue to operate the cell after active water flow from fluid source is discontinued. The cell is designed to passively circulate fluid entirely within the cell, allowing efficient continued filtration to occur. As a result, more efficient matching of the cell to the particular supplied environment may be achieved. Several alternative constructions of the cell are disclosed.

Abstract: An electrolytic filter system (16) is disclosed for use in treating fluid provided by a fluid source (12) to a supplied environment (14). The system includes an electrolytic cell (18), whose operation is governed by a control circuit (20) to allow a desired average current to be applied to the cell substantially independent of variations in fluid resistivity, to allow the cell to simultaneously achieve, for example, the desired removal of contaminants, killing of biological materials, and alteration of the fluid's chemical characteristics, and to provide relatively high levels of energy to the fluid quickly and efficiently.

Abstract: Liquid is clarified by passing it between spaced plates of a stack including two interleaved sets of plates, one set being connected to one direct current lead and the other set being connected to the other direct current lead. The liquid may flow through the spaces between the plates in a single direction in parallel paths or may flow in a serpentine path. Impurities removed from the liquid adhere to the plates and may be purged from the plates periodically by reversing the direction of flow of current between the plates. Impurities sloughed off the plates are trapped in a filter in the cell outlet.

Abstract: Liquid is clarified by passing it between spaced plates of a stack including two interleaved sets of plates, one set being connected to one direct current lead and the other set being connected to the other direct current lead. The liquid may flow through the spaces between the plates in a single direction in parallel paths or may flow in a serpentine path. Impurities removed from the liquid adhere to the plates and may be purged from the plates periodically by reversing the direction of flow of current between the plates. Impurities sloughed off the plates are trapped in a filter in the cell outlet.

Abstract: Regeneration of spent hydrochloric acid after use for pickling iron, which herefore contains iron chlorides, by electrolysis in the cathodic and intermediate compartments of an electrodialysis cell. The installation includes electric circuitry for connecting up the anode as well as input conduits for the spent acid but otherwise consists essentially of an electrodialysis cell with an uneven number of compartments wherein each cathodic compartment is separated from the adjacent intermediate compartment by an anion-selective membrane while a cation-selective membrane separates each intermediate compartment from the anodic compartment, the latter being filled with an anolyte whose total Faraday yield for water oxidation is close to 1. Electrolysis is conducted with current densities at the cathode of 0.1 - 20 A/dm.sup.2, at the anode corresponding to the water oxidation reaction and at the membranes such that their perm-selectivity is close to 1.