Publication number: 20080051348
Abstract: A method of treatment for treating, inhibiting, reducing or at least partly preventing respiratory or pulmonary microbial infection or gastrointestinal disorder of tissue of a subject, includes administering to a subject an effective amount of a composition including a polypeptide including thymosin ?4 (TB4), an isoform of TB4, an N-terminal variant of TB4, a C-terminal variant of TB4, LKKTET or a conservative variant thereof, LKKTNT or a conservative variant thereof, TB4 sulfoxide, TB4ala, T?9, T?10, T?11, T?12, T?13, T?14, T?15, gelsolin, vitamin D binding protein (DBP), profilin, cofilin, adsevertin, propomyosin, fincilin, depactin, Dnasel, vilin, fragmin, severin, capping protein, ?-actinin, acumentin or a combination thereof, so as to inhibit the infection or disorder.
Type:
Application
Filed:
July 3, 2007
Publication date:
February 28, 2008
Applicant:
RegeneRx Biopharmaceuticals, Inc.
Inventors:
Allan Goldstein, Jack Finkelstein, David Crockford