Patents Assigned to Regent of the University of Minnesota
  • Patent number: 4941313
    Abstract: A humane training aid comprising a collar loop and a muzzle loop that are mounted together to permit placement onto an animal such as a dog where the muzzle loop is slideably mounted through a ring held by the collar loop at the rear of the lower jaw and against the neck of the dog. The muzzle loop is placed over the muzzle of the animal. In order to make the humane training aide work effectively, the muzzle loop is made so that it closely fits the muzzle and has a portion that is positioned on the lower side of the ring held by the collar to which a leash can be attached so that upon applying a pulling force on the muzzle loop, the loop and the collar will provide pressure against the muzzle and neck of the animal to provide a calming effect and control. An adjustable slide-lock device is used to quickly adjust the muzzle loop. The slide-lock device has universal applications for adjusting loop sizes for various uses.
    Type: Grant
    Filed: July 22, 1988
    Date of Patent: July 17, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Robert K. Anderson, Ruth E. Foster, Bertyl W. Carlson
  • Patent number: 4940816
    Abstract: Acylated cyanamide compounds useful for ethanol deterrence of the formula RCONHCN, wherein R is a lipophilic acyl group or is derived from an (N-substituted)-alpha-aminoacyl group.
    Type: Grant
    Filed: July 19, 1989
    Date of Patent: July 10, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Herbert T. Nagasawa, Chul-Hoon Kwon
  • Patent number: 4932936
    Abstract: A method and apparatus for pharmacological control of spastic urethral sphincters, particularly in patients with spinal cord injuries, includes a special monopolar electrode/needle (30) adapted for insertion through a cystoscope (46) in electrical isolation therewith but connection with an electromyograph (12) for precise determination of injection sites so that a toxin, such as botulinum A, can be injected directly into skeletal muscle tissue, rather than connective tissue, to denervate and thus relax the sphincter.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: June 12, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Dennis D. Dykstra, Abraham A. Sidi
  • Patent number: 4931559
    Abstract: Antiviral and antitumor compounds are disclosed of general formula: ##STR1## wherein Z is H, OR' or NH.sub.2, wherein R' is H, (C.sub.1 -C.sub.4)alkyl, aryl, CHO, (C.sub.1 -C.sub.16)alkanoyl or O.dbd.P(OH).sub.2, Y is CH or N, and X is selected from the group consisting of H, N(R.sub.2), SR, OR' or halogen, wherein R is H, lower(C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically-acceptable salts thereof.
    Type: Grant
    Filed: December 5, 1988
    Date of Patent: June 5, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Robert Vince, Mei Hua
  • Patent number: 4928709
    Abstract: A device and process for measuring cervical range of motion about three axes comprises a frame which is supported on the nose of a subject and which has side temple pieces for locating the frame on the wearer's head. Cervical range of motion of a wearer's head can be measured through the use of gravity type angle meters and a magnetic type angle meter which are mounted on the frames and easily referenced back to the frame. The magnetic type angle meter is mounted above the head on a removable arm, which is supported on the frame. A magnetic field is created using magnets mounted on the subject to obtain reliable head rotation readings. The magnetic type angle meter can be removed, and an arm which is mounted on the frame and extends above the head of a wearer and which when coupled with a locator arm can determine a forward head position measurement.
    Type: Grant
    Filed: April 27, 1988
    Date of Patent: May 29, 1990
    Assignees: Regents of the University of Minnesota, Performance Attainment Associates, Inc.
    Inventors: John D. Allison, Gordon Hanson
  • Patent number: 4928707
    Abstract: A pressure algometer apparatus (50, 100) is provided. The pressure algometer apparatus (50, 100) provides a combination mechanical and electrical pressure algometer including a hand held pressure transducer (52, 102) electrically interconnected (53, 138) to an amplifier meter arrangement (54, 104). The algometer apparatus (50, 100) includes a pressure readout display (70, 144) which indicates the pressure sensed by the pressure transducer (52, 102). A recording device (150) may be attached to the algometer apparatus (100) to provide a permanent record (148) of the pressure sensed by the pressure transducer (102). The pressure algometer apparatus (100) further includes a latch device (106) which, when activated, holds the pressure readout display (144) constant and marks the permanent record (148).
    Type: Grant
    Filed: September 2, 1988
    Date of Patent: May 29, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Eric L. Schiffman, James R. Fricton, Lawrence M. Espy
  • Patent number: 4928537
    Abstract: A particle measurement apparatus for obtaining accurate information relating to airborne particles in a gas under vacuum from a process chamber including a sampling chamber which can be subjected to a very strong vacuum and used for obtaining a sample of the gas in the process chamber. The interior of the sampling chamber is first flushed with very clean purge gas, and subsequently opened to the process vacuum chamber which is to be sampled so that a sample of the atmosphere of gas from the process vacuum chamber is held in the sampling chamber. The sampling chamber is sealed from the process chamber and the sample is brought to atmospheric pressure by adding a particle-free purified gas. The sample is then flushed from the sampling chamber and passed through a particle counter. Calculations can then be made to determine the original particle concentration in the process vacuum chamber based on the measured particle concentration from the sample of the sampling chamber.
    Type: Grant
    Filed: December 6, 1988
    Date of Patent: May 29, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Benjamin Y. H. Liu, Wladyslaw W. Szymanski
  • Patent number: 4927300
    Abstract: A high speed steel, carbide or ceramic cutting insert or tool carrying an integrally mounted sensor to permit the sensor to sense and monitor machining phenomena on the cutting insert on a continuous basis to determine whether the cutting insert is operating efficiently and effectively.
    Type: Grant
    Filed: September 21, 1988
    Date of Patent: May 22, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Subbiah Ramalingam, Darrell A. Frohrib
  • Patent number: 4927299
    Abstract: An acoustic emission sensor comprising a piezoelectric material that is integral with a tooling or machine element in which acoustic emissions are to be sensed.
    Type: Grant
    Filed: April 24, 1989
    Date of Patent: May 22, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Subbiah Ramalingam, Darrell A. Frohrib
  • Patent number: 4927407
    Abstract: A centrifugal pump for left ventricle assist includes a pump housing forming an impeller chamber with inlet and outlet passages and enclosing an impeller rotatable to move blood through the impeller chamber, and a rotor chamber enclosing a rotor integral with the impeller and rotatable to drive the impeller. An elastically deformable seal member separates the rotor and impeller chambers, and includes an annular lip seal surrounding a shaft which joins the impeller and rotor. A saline solution is supplied at a constant fluid flow rate to the rotor chamber through an inlet passage, and leaves the rotor chamber by perfusing into the impeller chamber along the interface between the shaft and lip seal. The saline solution thus provides hydrodynamic bearings between the rotating shaft and rotor, and the fixed pump housing and lip seal, and further prevents blood in the impeller chamber from entering the rotor chamber.
    Type: Grant
    Filed: June 19, 1989
    Date of Patent: May 22, 1990
    Assignee: Regents of the University of Minnesota
    Inventor: Frank Dorman
  • Patent number: 4923717
    Abstract: A method for forming aluminum films is provided comprising employing the techniques of chemical vapor deposition to thermally decompose a vapor comprising a aluminum hydride subsequent to the treatment of the substrate with a Group IVB or VB metal complex, so as to deposit a mirror-like coating of aluminum on the surface of a substrate.
    Type: Grant
    Filed: March 17, 1989
    Date of Patent: May 8, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Wayne L. Gladfelter, David C. Boyd
  • Patent number: 4916224
    Abstract: Antiviral and antitumor compounds are disclosed of general formula: ##STR1## wherein Z is H, OH or NH.sub.2, Y is CH or N, the bond indicated by C.sub.1 '--C.sub.2 ' is absent or, in combination with the C.sub.1 '--C.sub.2 ' bond is the unit CH.dbd.CH, and X is selected from the group consisting of H, N(R.sub.2), SR, OR or halogen, wherein R is H, lower (C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: January 20, 1988
    Date of Patent: April 10, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Robert Vince, Mei Hua
  • Patent number: 4911706
    Abstract: An automatic needle cover is mounted onto the base of a hypodermic needle on a syringe and leaves the needle exposed for initial use, such as for withdrawing blood or the like. A releasable tab is either cut or released, and a resilient support arm pushes a protective cap out past the end of the needle, to cover the end of the needle and prevent an accidental pricking of the user's skin. The contents of the syringe can drip freely out of the cap, or if desired, the cap can be braced against a depression in a rubber stopper of a container, to thereby facilitate realigning the hole in the cap with the needle, so that the needle contents can be discharged into the container. The protective cap is made so that it moves laterally to insure covering the point of the needle so that the point will not accidentally protrude.
    Type: Grant
    Filed: October 14, 1988
    Date of Patent: March 27, 1990
    Assignee: Regents of the University of Minnesota
    Inventor: Michael D. Levitt
  • Patent number: 4908317
    Abstract: A thermophilic-acidophilic alga, strains of Cyanidium caldarium, is disclosed as having a very effective external uptake of metals from metal-containing aqueous media. A process is disclosed for producing at least one polysaccharide comprises contacting an acidic aqueous medium containing at least one added metal selected from the group consisting of alkali metals, alkaline earth metals, aluminum and mixtures thereof and at least one acidophilic microorganism at conditions effective for the growth of the microorganism and the production of polysaccharide by the microorganism.
    Type: Grant
    Filed: October 14, 1986
    Date of Patent: March 13, 1990
    Assignee: The Regents of the University of Minnesota
    Inventors: John M. Wood, Francis E. Engle
  • Patent number: 4905059
    Abstract: A radiation-emitting semiconductor device (i.e. an LED or laser) emits radiation produced by radiative recombination of electrons from a field induced two-dimensional (2-d) electron gas with holes from a field induced two-dimensional (2-d) hole gas. The device uses a narrower band semiconductor active layer sandwiched between two layers of a wider band semiconductor. Top and bottom gates are used to induce the electron and hole 2-d gasses in the active layer. N+ and P+ regions are used to contact the 2-d electron and hole gasses to provide separate biasing. The thickness of the active layer is such that a field induced PN junction or PIN structure is formed at which radiative recombination can occur.
    Type: Grant
    Filed: September 19, 1988
    Date of Patent: February 27, 1990
    Assignee: Regents of the University of Minnesota
    Inventor: Michael Shur
  • Patent number: 4899758
    Abstract: Apparatus and method for monitoring and diagnosing CHF and hypertension includes digitizing brachial artery pulses and determining C.sub.2 from modified Windkessel model. CHF and hypertension are monitored and diagnosed by tracking C.sub.2 values and testing values against a disease discriminating threshold of 0.08 ml/mm Hg.
    Type: Grant
    Filed: August 2, 1988
    Date of Patent: February 13, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Stanley M. Finkelstein, Jay N. Cohn
  • Patent number: 4901122
    Abstract: A hot electron transistor includes two base regions between the emitter and collector, with the first and second bases separated by a base-base barrier. The emitter injects high energy electrons across an emitter barrier into the first base, which acts as an electron gun to focus and accelerate the electrons and inject them across the base-base barrier into the second base. An input signal is applied to the second base, to modulate the flow of electrons from the second base across a collector barrier and into the collector.
    Type: Grant
    Filed: March 22, 1989
    Date of Patent: February 13, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Jingming Xu, Michael Shur
  • Patent number: 4899200
    Abstract: A high-speed heterostructure planar integrated circuit includes a planar photodetector together with a transistor (either a Modulation-Doped Field Effect Transistor or a lateral p-n-p bipolar transistor). The planar photodetector includes a bottom confinement layer of a wide bandgap material, a heavily doped first conductivity-type buried layer over the bottom confinement layer, a relatively undoped higher index of refraction layer overlying the buried layer, a top confinement layer of wider bandgap material which has a lower index of refraction, a first vertical contact region of first conductivity type which extends downward to make electrical contact with the buried layer, and a second contact region of second conductivity type spaced laterally from the first contact region and extending through the top confinement layer and a portion of the undoped layer.
    Type: Grant
    Filed: June 3, 1988
    Date of Patent: February 6, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Michael Shur, John G. Simmons
  • Patent number: PP7197
    Abstract: An apple tree having a slightly upright form with moderately vigorous growth; a superior fruit with solid to mottled red color over a yellow background and a crisp and juicy fruit texture; an extended season of harvest but with generally even ripening of fruit so that repeat pickings are unnecessary; good hardiness with little winter injury when grown near Excelsior, Minn. at approximately 45.degree. latitude; and having annual fruit production with no flower thinning required.
    Type: Grant
    Filed: November 7, 1988
    Date of Patent: March 20, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Jim Luby, David S. Bedford
  • Patent number: PP7269
    Abstract: A new variety of Dendranthema grandiflora (Chrysanthemum morifolium Ramat.) for the outdoor garden and for spring flowering greenhouse pot plant culture, characterized by flowers which are early opening, rich dark-red in color, slow fading, fully double, flat decorative, and 7.5-9 cm in diameter in an open spray formation. This plant is unique within its color range for earliness, size of bloom and color retention.
    Type: Grant
    Filed: November 21, 1988
    Date of Patent: July 10, 1990
    Assignee: Regents of the University of Minnesota
    Inventor: Richard E. Widmer