Patents Assigned to Regents for the University of Oklahoma
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Publication number: 20240148831Abstract: A method of treating a cholestasis liver condition in a subject by administering to the subject a first compound and a second compound, wherein the first compound is a fibroblast growth factor 19 (FGF19) analogue, and/or a bile acid-activated farnesoid x receptor (FXR) agonist, and the second compound is an apical sodium-dependent bile acid transporter (ASBT) inhibitor.Type: ApplicationFiled: November 2, 2023Publication date: May 9, 2024Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMAInventor: Tiangang LI
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Publication number: 20240116857Abstract: In one aspect, the present disclosure provides compounds such as those with one or more quaternary ammonium ions joined by one or more aromatic rings. These compounds may have a formula: These compounds may be used in the treatment of a microbial infection such as a bacterial infection including infections of drug resistant strains of bacteria.Type: ApplicationFiled: July 6, 2023Publication date: April 11, 2024Applicants: Saint Louis University, The Board of Regents of the University of OklahomaInventors: John K. WALKER, Valentin V. RYBENKOV, Ramakumar KINTHADA, Hang ZHAO, Elena I. ZGURSKAYA, Terri BOEHM, Zoya PETRUSHENKO
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Patent number: 11905671Abstract: A sorbent-based oil skimmer is configured to collect oil from an oil layer and passively deposit the oil in an encasing, where the oil can be continuously or periodically removed. The oil skimmer includes an encasing and a sponge that is partially enclosed within the encasing. The sponge has a top sheet in contact with the oil layer and a shell connected to the top sheet, where the shell extends into the encasing. Oil collected by the top sheet is conveyed through the shell, where it is deposited into the encasing under the force of gravity. In some applications, the sponge is manufactured from a silicone-based polymer that has been impregnated with carbonaceous material. The skimmer may optionally include counterweights, ballast tanks, buoyancy adjustment systems and propulsion modules.Type: GrantFiled: January 21, 2022Date of Patent: February 20, 2024Assignee: The Board of Regents of the University of OklahomaInventors: Blake A. Herren, Yingtao Liu, M. Cengiz Altan, Mrinal C. Saha
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Patent number: 11884710Abstract: Peptide compounds and compositions containing the peptide compounds and methods for treating various infections, wounds, and skin conditions such as atopic dermatitis. Examples of wounds that may be treated include surface wounds such as lacerations, abrasions, avulsions, incisions, and amputations, pressure sores, bed sores, wounds due to peripheral vascular disease, post-surgical wounds, diabetic ulcers and wounds, burns, ocular wounds and abrasions, ocular ulcers, and treatment of inflammatory conditions such as dry eye. The peptide compounds and compositions may be used as treatments to enhance acceptance of grafts such as skin grafts and organ grafts.Type: GrantFiled: November 22, 2021Date of Patent: January 30, 2024Assignee: The Board of Regents of the University of OklahomaInventors: Heloise Anne Pereira, Anne Kasus-Jacobi, Gina L. Griffith
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Patent number: 11867738Abstract: An apparatus for a mmWave RF scanner system is described that enables multiple modes of operation. The disclosed RF scanner may be configured to perform a variety of independent tasks, including antenna measurement in far-field or near-field mode, active array characterization, radome measurements, and material characterization. To achieve all proposed measurements, a nine-axis RF scanner system is disclosed. For all modes, the system may use a two-port vector network analyzer (100 kHz to 9 GHz) connected to a plurality of frequency extenders that increases the operating range from 75 GHz to 110 GHz. The system may also include a graphical user interface for autonomous operation in each mode.Type: GrantFiled: June 30, 2021Date of Patent: January 9, 2024Assignee: The Board of Regents of the University of OklahomaInventor: Jorge Luis Salazar-Cerreno
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Patent number: 11857651Abstract: A dental composition comprising doped T1O2 nanoparticles, and a curable resin material, wherein the curable resin material comprises a polymer precursor component, and wherein the dopant may be one or more of, for example, N (nitrogen), Ag (silver), F (fluorine), P (phosphorus), and P04 (phosphate). A method of using the dental composition in a dental application. The dental composition may be antibacterial in the absence of visible light or UV light.Type: GrantFiled: December 7, 2017Date of Patent: January 2, 2024Assignees: The Board of Regents of the University of Oklahoma, UT-Battelle, LLCInventors: Fernando Luis Esteban Florez, Sharukh Soli Khajotia, Adam Justin Rondinone
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Patent number: 11851503Abstract: Novel compositions and methods for the treatment and prevention of malaria are disclosed herein.Type: GrantFiled: January 24, 2022Date of Patent: December 26, 2023Assignees: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC., THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMAInventors: Debopam Chakrabarti, Robert H. Cichewicz, Shengxin Cai, Jin Woo Lee, Jennifer E. Collins
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Publication number: 20230404827Abstract: An aerosol containment device is designed for use in containing aerosols discharged during a dental procedure. In some embodiments, the aerosol containment device includes a vacuum source, a vacuum hose connected to the vacuum source, a manifold connected to the vacuum hose, and a clear plastic shield connected to the manifold. The manifold includes a front inlet, a rear discharge connected to the vacuum hose, and a plenum extending between the front inlet and the rear discharge. In some embodiments, the manifold includes a plurality of entry vanes adjacent to the front inlet and a plurality of interior foils connected to the entry vanes. In other embodiments, the manifold includes a plurality of entry vanes adjacent to the front inlet and a plurality of interior vanes connected to the entry vanes. In other embodiments, the manifold does not include entry vanes, interior vanes, or interior foils.Type: ApplicationFiled: November 7, 2021Publication date: December 21, 2023Applicant: The Board of Regents of the University of OklahomaInventors: Fernando Luis Esteban Florez, Tyler G. Thibodeau, Paul M. Mullasseril, Sharuhk S. Khajotia, C. Rieger Wood, III, Michael Ferguson
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Patent number: 11839642Abstract: Carrier compositions, including human-safe phages, equipped with one or more angiogenin-binding peptides, and optionally with tumor-homing peptides for use in anti-tumor therapies, are described. The angiogenin-binding peptides bind to and inactivate angiogenin molecules thereby blocking their angiogenic activity thus inhibiting angiogenesis in the tissue in which the compositions are localized.Type: GrantFiled: April 9, 2019Date of Patent: December 12, 2023Assignee: The Board of Regents of the University of OklahomaInventors: Chuanbin Mao, Yan Li
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Publication number: 20230396917Abstract: Systems and methods for treating misophonia include utilizing machine learning within a deep learning processor to allow a user to listen to ambient sounds from their environment without hearing trigger sounds.Type: ApplicationFiled: June 1, 2023Publication date: December 7, 2023Applicant: The Board of Regents of the University of OklahomaInventor: Elijah Robertson
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Publication number: 20230348396Abstract: Hydroxybenzamide derivative compounds having ?-cell protective activity against ER stress, and methods of their use in treating diabetes and other conditions and diseases associated with ER stress. In one non-limiting embodiment, the derivative is 3-hydroxy-N-(4-(trifluoromethyl)benzyl)benzamide.Type: ApplicationFiled: April 28, 2023Publication date: November 2, 2023Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMAInventors: Venkateswararao EEDA, Weidong WANG
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Patent number: 11796580Abstract: A probe is described. The probe includes a probe antenna, a transmitter, a receiver and circuitry including hardware. The probe antenna is constructed of a dielectric material connected to a waveguide, the probe antenna has a far field region. The transmitter is coupled to the probe antenna. The receiver is coupled to the probe antenna. The hardware is configured to communicate with the transmitter to enable the transmitter to direct a pulse of electromagnetic energy to the probe antenna and to receive a reflection signal from the receiver, the hardware is configured to determine a material property of a material within the far-field region of the probe antenna by analyzing the reflection signal.Type: GrantFiled: April 23, 2018Date of Patent: October 24, 2023Assignee: The Board of Regents of the University of OklahomaInventors: Jorge Luis Salazar Cerreno, Alessio Mancini, Boon Leng Cheong
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Patent number: 11744565Abstract: A surgical evacuation apparatus and method for evacuating a biological material from a body cavity. The surgical evacuation apparatus has a shaft and a scoop extending from a distal end of the shaft. The shaft has a supply inlet for connecting to a pressurized fluid source and an outlet for connecting to a vacuum source. An evacuation channel extends from the scoop to the outlet. A fluid supply channel extends in the shaft from the supply inlet towards the distal end and intersects the evacuation channel proximate the scoop. Material desired to be removed from the body cavity is collected in the scoop by a user. The biological material collected in the scoop is broken up by a fluid stream from the supply channel and is drawn into the evacuation channel by a vacuum applied by the vacuum source and is removed from the body cavity.Type: GrantFiled: September 28, 2018Date of Patent: September 5, 2023Assignee: The Board of Regents of the University of OklahomaInventor: Jason Lees
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Patent number: 11749770Abstract: A photovoltaic device configured to substantially avoid radiative recombination of photo-generated carriers, reduce loss of energy of the photo-generated carriers through the phonon emission, extract photo-generated carriers substantially exclusively from the multi-frequency satellite valley(s) of the bandstructure of the used semiconductor material as opposed to the single predetermined extremum of the bandstructure. Methodologies of fabrication and operation of such a device.Type: GrantFiled: October 14, 2019Date of Patent: September 5, 2023Assignees: Arizona Board of Regents on behalf of Arizona State University, The Board of Regents of the University of OklahomaInventors: David Ferry, Vincent Whiteside, Ian R. Sellers
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Publication number: 20230261609Abstract: A mounting system for mounting a solar panel assembly to a base assembly includes a panel support bracket, a base bracket and a clamp configured to exert a compressive force to hold the panel support bracket and the base bracket together. The clamp comprises a V-shaped clamp body that includes a pair of legs that are spring-loaded to oppose an approximation of the legs by an external compressive force. The clamp includes a pair of receiver slots, with each of the pair of receiver slots located on a corresponding one of the pair of legs. The pair of receiver slots collectively provides a clearance to admit the panel support bracket and the base bracket when the legs are compressed together.Type: ApplicationFiled: November 17, 2022Publication date: August 17, 2023Applicant: The Board of Regents of the University of OklahomaInventor: Andres F. Cavieres Pinilla
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Patent number: 11691358Abstract: A liquid composite molding method includes the steps of providing a part mold that has an inlet gate and an exit gate, placing a fabric preform over the part mold, placing a membrane over the fabric preform and securing a pressure cap to the part mold. The pressure cap and part mold together form a pressure chamber with a headspace between the membrane and the pressure cap. The method further includes the step of filling the fabric preform with liquid resin under the membrane while applying pressure within the headspace over the membrane. The method may be practiced with an apparatus that has a pressure chamber, a fabric preform inside the pressure chamber, a membrane over the fabric preform, a resin injection assembly, and a resin extraction assembly. The pressure chamber includes a part mold and a pressure cap. A headspace is formed above the membrane within the pressure chamber.Type: GrantFiled: July 3, 2020Date of Patent: July 4, 2023Assignee: The Board of Regents of the University of OklahomaInventors: M Cengiz Altan, Mehmet Akif Yalcinkaya
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Patent number: 11672789Abstract: Provided are methods useful for preventing and mitigating radiation injury, including acute radiation syndrome, comprising administering to a subject a therapeutically effective amount of a compound represented by formula I or a pharmaceutically acceptable salt thereof, wherein Z is —O— or —N(H)—.Type: GrantFiled: April 25, 2022Date of Patent: June 13, 2023Assignees: Georgetown University, The Board of Regents of the University of OklahomaInventors: Milton L. Brown, Yali Kong, Courtney Houchen, Sripathi M. Sureban, Parthasarathy Chandrakesan
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Patent number: 11655307Abstract: Antibodies and antigen-binding fragments thereof that specifically bind to human DCLK1 protein, hybridomas or other cell lines which express such antibodies and antigen-binding fragments thereof, nucleic acids, vectors, and host cells comprising nucleic acids which encode such antibodies and antigen-binding fragments thereof, and methods of use thereof are disclosed. In at least certain non-limiting embodiments, the antibodies or antigen-binding fragments thereof specifically bind to an epitope within isoform 2 or 4 of DCLK1 protein.Type: GrantFiled: May 30, 2018Date of Patent: May 23, 2023Assignee: The Board of Regents of the University of OklahomaInventors: Courtney W. Houchen, Nathaniel Weygant, Dongfeng Qu, Randal May, Parthasarathy Chandrakesan, William L. Berry
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Patent number: 11644442Abstract: A method and system of nanoscale photoacoustic tomography (nPAT) for non-invasive three-dimensional mapping and characterization of fine cellular structures (such as but not limited to organelles, vesicles, and macromolecules) of biological samples is disclosed.Type: GrantFiled: March 31, 2017Date of Patent: May 9, 2023Assignee: The Board of Regents of the University of OklahomaInventors: Liangzhong Xiang, Jian Chen, Pratik Samant
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Patent number: D994040Type: GrantFiled: February 15, 2021Date of Patent: August 1, 2023Assignee: The Board of Regents of the University of OklahomaInventor: Jennifer Thompson Tetnowski