Patents Assigned to Regents of the University of California, San Diego UCSD Technology Transfer Office
  • CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR
    Publication number: 20120148660
    Abstract: The invention provides TLR agonists and conjugates thereof useful in vaccines and to prevent, inhibit or treat a variety of disorders including pathogen infection and asthma.
    Type: Application
    Filed: February 7, 2008
    Publication date: June 14, 2012
    Applicant: Regents of the University of California, San Diego UCSD Technology Transfer Office
    Inventors: Dennis A. Carson, Howard B. Cottam, Wolfgang Wrasidlo, Christina C.N. Wu, Gregory A. Daniels
  • METALLOPROTEIN INHIBITORS
    Publication number: 20090286987
    Abstract: The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and each R1, R2, R3, and R4 is individually hydrogen or an organic radical. The metalloprotein inhibitors are useful for preventing or treating a pathological disease, condition, or symptom that is associated with pathological metalloprotein activity and/or that is alleviated by inhibition of said activity.
    Type: Application
    Filed: July 15, 2009
    Publication date: November 19, 2009
    Applicant: Regents of the University of California, San Diego UCSD Technology Transfer Office
    Inventors: David T. Puerta, Seth M. Cohen, Jana A. Lewis
  • Metalloprotein Inhibitors
    Publication number: 20080161362
    Abstract: The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and each R1, R2, R3, and R4 is individually hydrogen or an organic radical. The metalloprotein inhibitors are useful for preventing or treating a pathological disease, condition, or symptom that is associated with pathological metalloprotein activity and/or that is alleviated by inhibition of said activity.
    Type: Application
    Filed: April 28, 2005
    Publication date: July 3, 2008
    Applicant: Regents of the University of California, San Diego UCSD Technology transfer office
    Inventors: David T. Puerta, Seth M. Cohen, Jana A. Lewis