Patents Assigned to Regents of the University of Minnesota and Rutgers
  • Biotherapeutic agents comprising recombinant PAP and PAP mutants
    Patent number: 6146628
    Abstract: Biotherapeutic agents are provided which comprise recombinant PAP or a biologically equivalent variant or mutant thereof, linked to a targeting moiety which are effective for the treatment of certain human diseases. The invention further provides a process for producing the biotherapeutic agents as well as a method which utilizes the disclosed biotherapeutic agents to systemically treat cancer patients.
    Type: Grant
    Filed: July 11, 1995
    Date of Patent: November 14, 2000
    Assignees: Regents of the University of Minnesota and Rutgers, The State University of New Jersey
    Inventors: Fatih M. Uckun, Nilgun E. Tumer