Patents Assigned to Regulus Therapeutics, LLC
  • ANTISENSE COMPOUNDS HAVING ENHANCED ANTI-MICRORNA ACTIVITY
    Publication number: 20090203893
    Abstract: Antisense compounds, compositions and methods are provided for modulating the levels expression, processing and function of miRNAs. The antisense compounds exhibit enhanced anti-miRNA activity. Further provided are methods for enhancing the inhibitory activity of an antisense compound targeting a miRNA, comprising incorporating stability enhancing sugar modifications into the antisense compounds.
    Type: Application
    Filed: August 29, 2006
    Publication date: August 13, 2009
    Applicant: Regulus Therapeutics, LLC
    Inventors: Christine E. Esau, Eric Swayze