Patents Assigned to Relia Diagnostic Systems, LLC
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Patent number: 8703494Abstract: Described herein are systems and methods for assaying a sample to quantitatively determine the percentage of glycated hemoglobin in the sample.Type: GrantFiled: May 20, 2010Date of Patent: April 22, 2014Assignee: Relia Diagnostic Systems, LLCInventors: William J. Rutter, Jang H. Han, Taewoo Kwon
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Patent number: 8003407Abstract: The present invention relates to a lateral flow assay and system, including a test strip, for detection and quantification of analytes in samples, such as samples containing cells and fluid. In general, according to the present invention, a test strip for a lateral flow assay for detection of at least one analyte in a sample comprises: (1) a chromatographic strip, a sample filter, a fluid-impermeable barrier, and means for providing a mobilizable detectable agent that is capable of binding to the at least one analyte or to the capture agent after capturing the analyte to the chromatographic strip such that the mobilizable detectable agent migrates through the chromatographic strip and contacts sample that has passed through the sample filter and also has migrated through the chromatographic strip. The test strip allows detection with or without quantitation of an analyte in a sample containing whole cells.Type: GrantFiled: July 29, 2005Date of Patent: August 23, 2011Assignee: Relia Diagnostic Systems, LLCInventors: Siliang Zhou, William Rutter, Ning Liu
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Publication number: 20100092945Abstract: A test strip for conducting a lateral flow assay for detection of an analyte in a sample that contains cells and fluid is provided, as well as methods for making and using the test strip. This test strip is commercially usable, for example, in a diagnostic device at a point of care for detection of analytes in whole blood.Type: ApplicationFiled: October 16, 2009Publication date: April 15, 2010Applicant: RELIA DIAGNOSTIC SYSTEMS, LLCInventor: Siliang Zhou
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Patent number: 7605004Abstract: A test strip for conducting a lateral flow assay for detection of an analyte in a sample that contains cells and fluid is provided, as well as methods for making and using the test strip. This test strip is commercially usable, for example, in a diagnostic device at a point of care for detection of analytes in whole blood.Type: GrantFiled: July 18, 2002Date of Patent: October 20, 2009Assignee: Relia Diagnostic Systems LLCInventor: Siliang Zhou
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Patent number: 7521196Abstract: A test strip and method for detecting an analyte present in a sample.Type: GrantFiled: June 7, 2007Date of Patent: April 21, 2009Assignee: ReLia Diagnostic Systems, LLCInventors: Robert K. Dinello, Alan J. Polito, Stella Quan
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Publication number: 20080031779Abstract: An embodiment of the present invention provides a method for performing a lateral flow assay. The method includes depositing a sample on a test strip at an application region, detecting a first detection signal arising from the test strip in the first detection zone, and generating a baseline for the first measurement zone by interpolating between values of the detection signal outside of the first measurement zone and inside of the first detection zone. The method may include locating a beginning boundary and an ending boundary for the first measurement zone on the test strip. Additional detection zones having measurement zones may also be incorporated with the embodiment.Type: ApplicationFiled: October 8, 2007Publication date: February 7, 2008Applicant: RELIA DIAGNOSTIC SYSTEMS, LLCInventors: Alan Polito, Richard Thayer, Robert DiNello, George Sierra, Dennis Nixon, Alan Phillips, Stuart Neubarth
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Patent number: 7309611Abstract: A test strip and method for detecting an analyte present in a sample.Type: GrantFiled: June 14, 2004Date of Patent: December 18, 2007Assignee: Relia Diagnostic Systems, LLCInventors: Robert K. DiNello, Alan J. Polito, Stella S. Quan
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Publication number: 20070283747Abstract: A test strip and method for detecting an analyte present in a sample.Type: ApplicationFiled: June 7, 2007Publication date: December 13, 2007Applicant: RELIA DIAGNOSTIC SYSTEMS, LLCInventors: Robert DiNello, Alan Polito, Stella Quan
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Patent number: 7297529Abstract: An embodiment of the present invention provides a method for performing a lateral flow assay. The method includes depositing a sample on a test strip at an application region, detecting a first detection signal arising from the test strip in the first detection zone, and generating a baseline for the first measurement zone by interpolating between values of the detection signal outside of the first measurement zone and inside of the first detection zone. The method may include locating a beginning boundary and an ending boundary for the first measurement zone on the test strip. Additional detection zones having measurement zones may also be incorporated with the embodiment.Type: GrantFiled: August 4, 2003Date of Patent: November 20, 2007Assignee: Relia Diagnostic Systems, LLCInventors: Alan J. Polito, Richard M. Thayer, Robert K. DiNello, George H. Sierra, Dennis Nixon, Alan Phillips, Stuart Neubarth
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Patent number: 7229839Abstract: A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to the sample addition zone, at least one of the test zones including a first analyte binding agent immobilized therein which is capable of binding to the analyte to be detected; and a terminal sample flow zone distal to the one or more test zones, the absorbent zone being positioned relative to the sample addition zone and having an absorption capacity relative to the other zones of the test strip such that a distal diffusion front of a sample added to the sample addition zone diffuses from the sample addition zone to a distal diffusion point within the terminal sample flow zone and then reverses direction and diffuses proximal relative to the one or more test zones.Type: GrantFiled: January 17, 2003Date of Patent: June 12, 2007Assignee: Relia Diagnostic Systems, LLCInventors: Richard M. Thayer, Alan J. Polito, Robert K. Dinello, George H. Sierra, Henry J. Wieck