Patents Assigned to Reliable Biopharmaceutical, Inc.
  • POLYMERIC NUCLEOSIDE PRODRUGS
    Publication number: 20100081627
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: October 2, 2009
    Publication date: April 1, 2010
    Applicant: RELIABLE BIOPHARMACEUTICAL, INC.
    Inventors: UmaShanker Sampath, Joseph A. Toce, Sourena Nadji
  • POLYMERIC NUCLEOSIDE PRODRUGS
    Publication number: 20070179112
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: January 29, 2007
    Publication date: August 2, 2007
    Applicant: Reliable Biopharmaceutical, Inc.
    Inventors: UmaShanker Sampath, Joseph Toce, Sourena Nadji
  • Process for the production of 2-halo-6-aminopurine derivatives
    Patent number: 6596858
    Abstract: A novel process for preparing 2-halo-6-aminopurine derivatives and their analogs is disclosed. The method comprises halogenation of 2,6-diaminopurine derivatives at the C-2 position in a specific combination of aprotic polar and nonpolar organic solvents to give the corresponding halogenated derivatives.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: July 22, 2003
    Assignee: Reliable Biopharmaceutical, Inc.
    Inventors: UmaShanker Sampath, Lawrence Bartlett
  • Process for the production of 2-halo-6-aminopurine derivatives
    Publication number: 20020052492
    Abstract: A novel process for preparing 2-halo-6-aminopurine derivatives and their analogs is disclosed. The method comprises halogenation of 2,6-diaminopurine derivatives at the C-2 position in a specific combination of aprotic polar and nonpolar organic solvents to give the corresponding halogenated derivatives.
    Type: Application
    Filed: March 12, 2001
    Publication date: May 2, 2002
    Applicant: Reliable Biopharmaceutical, Inc.
    Inventors: Sampath UmaShanker, Bartlett Lawrence
  • Polymeric compounds useful as prodrugs
    Publication number: 20020013287
    Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
    Type: Application
    Filed: May 9, 2001
    Publication date: January 31, 2002
    Applicant: Reliable Biopharmaceuticals, Inc. St Louis Missouri
    Inventors: UmaShanker Sampath, Joseph A. Toce, Sourena Nadji
  • Process for the production of 2-halo-6-aminopurine derivatives
    Patent number: 6252061
    Abstract: A novel process for preparing 2-halo-6-aminopurine derivatives and their analogs is disclosed. The method comprises halogenation of 2,6-diaminopurine derivatives at the C-2 position in a specific combination of aprotic polar and nonpolar organic solvents to give the corresponding halogenated derivatives.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: June 26, 2001
    Assignee: Reliable Biopharmaceutical, Inc.
    Inventors: UmaShanker Sampath, Lawrence Bartlett