Abstract: Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H—, alkyl or alkenyl phosphonate group.
Type:
Application
Filed:
May 9, 2001
Publication date:
January 31, 2002
Applicant:
Reliable Biopharmaceuticals, Inc. St Louis Missouri
Inventors:
UmaShanker Sampath, Joseph A. Toce, Sourena Nadji