Patents Assigned to Renal Tech International
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Patent number: 6632752Abstract: An article of clothing has a clothing part adapted to surround and cover a user's body, and a layer of a polymeric adsorbing material applied on the clothing part and formed so as to retain at least some toxic components of a poison gas so as to prevent penetration of the some toxic components to a user's body.Type: GrantFiled: February 14, 2001Date of Patent: October 14, 2003Assignee: Renal Tech International LLCInventor: James Winchester
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Patent number: 6589224Abstract: A method of introducing a fluid into a patient's body has the steps of accommodating the fluid in a plastic container, connecting an introducer to the plastic container so that the fluid can flow from the plastic container through the introducer into a patient's body, and arranging an adsorbing material between the plastic container and the introducer so that the fluid flows from the plastic container first through the adsorbing material, at least some toxins from the fluid are adsorbed by and retained on the adsorbing material, while the fluid purified from at least some toxins is introduced by the introducer into a patient's body.Type: GrantFiled: February 14, 2001Date of Patent: July 8, 2003Assignee: Renal Tech International LLCInventor: James Winchester
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Patent number: 6582811Abstract: A method of purification of physiological liquids of organism has the step of passing a physiological liquid through a material which has a size, a shape, and a structure selected so as to remove toxic compounds from the physiological liquid and is composed of a partially chloromethylated porous highly crosslinked styrene or divinylbenzene copolymer which initially have surface exposed chloromethyl groups in which thereafter chlorine is replaced with an element which forms different surface exposed functional groups with a greater hydrophilicity and greater biocompatibility than that of the chloromethyl group.Type: GrantFiled: July 13, 1999Date of Patent: June 24, 2003Assignee: Renal Tech International LLCInventors: Vedirn Davankov, Maria Tsyurupa, Ludmilla Pavlova, Dzidra Tur
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Patent number: 6531523Abstract: A beaded polymeric adsorbent has a core part; a shell part arranged around the core part, with one of the parts having a lipophilic property and another of the parts having a hydrophilic property, and is produced by preparing an organic phase composed of water insoluble monounsaturated and poly unsaturated comonomers; preparing an aqueous phase composed of a mixture of water soluble monounsaturated and polyunsaturated comonomers; forming a dispersion of the organic phase and the aqueous phase in a single vessel; and creating conditions for first polymerizing of one of the phases which forms the core part and thereafter polymerizing the other of the phases which forms the shell part.Type: GrantFiled: October 10, 2000Date of Patent: March 11, 2003Assignee: Renal Tech International, LLCInventors: Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova
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Publication number: 20020198487Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in physiologic fluid by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.Type: ApplicationFiled: December 21, 2001Publication date: December 26, 2002Applicant: Renal Tech InternationalInventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, Jamie A. Salsberg
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Publication number: 20020197251Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.Type: ApplicationFiled: December 21, 2001Publication date: December 26, 2002Applicant: Renal Tech InternationalInventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, Jamie A. Salsberg
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Publication number: 20020197249Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.Type: ApplicationFiled: December 21, 2001Publication date: December 26, 2002Applicant: Renal Tech InternationalInventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, Jamie A. Salsberg
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Publication number: 20020197252Abstract: Intravenous, or indwelling, or integrated multi-functional devices and systems reduce levels of a targeted compound in blood by selective adsorption. The devices and systems can be used, e.g., to reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices and systems are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices and systems serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.Type: ApplicationFiled: December 21, 2001Publication date: December 26, 2002Applicant: Renal Tech InternationalInventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, Jamie A. Salsberg
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Publication number: 20020197250Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.Type: ApplicationFiled: December 21, 2001Publication date: December 26, 2002Applicant: Renal Tech InternationalInventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, Jamie A. Salsberg
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Patent number: 6497675Abstract: A device for extracorporeal treatment of physiological fluids of organism has means forming a filtration membrane for filtering smaller-size components of a physiological fluid withdrawn from a patient from larger-size components of the same, a bed of particulate adsorbing material with which the smaller-size components are contacted for purification, and means for combining the purified smaller-size components of the fluid with the larger-size components of the fluid for returning the thusly treated fluid to a patient.Type: GrantFiled: April 17, 2000Date of Patent: December 24, 2002Assignee: Renal Tech International LLCInventor: Vadim Davankov
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Publication number: 20020159995Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.Type: ApplicationFiled: December 21, 2001Publication date: October 31, 2002Applicant: Renal Tech InternationalInventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, Jamie A. Salsberg
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Patent number: 6436579Abstract: An electrical battery has a plurality of pairs each including a positive active mass arranged in an impermeable horizontally located cuvette with an open upper surface, and a negative active mass arranged in an impermeable horizontally located cuvette and having an upper lower working surface with the second mentioned cuvette located above the first mentioned cuvette, the pairs being located one above the other, an electrolyte in which the cuvettes with the active masses are located, and means for electrically connecting in series the pairs of the cuvettes located one above the other.Type: GrantFiled: April 21, 2000Date of Patent: August 20, 2002Assignee: Renal Tech International LLCInventor: Timofei Gutkin
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Patent number: 6416487Abstract: A method of removing beta-2 microglobulin from blood, plasma and the like, has the steps of removing blood from a patient, passing the blood through an ADSORBENT material with a size and a structure selected so as to remove beta-2 microglobulin from the blood, and re-entering the blood from which the beta-2 microglobulin is removed into the patient.Type: GrantFiled: April 19, 1999Date of Patent: July 9, 2002Assignee: Renal Tech International LLCInventors: Andrew Braverman, Vadim Davankov
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Patent number: 6303702Abstract: Disclosed is a method for producing material for purification of physiological liquids of organism. A material has a size, shape and structure selected so as to remove toxic compounds in the molecular range of 300 to 3000 Dalton, and the material is produced from a porous hydrophobic divinylbenzne copolymer, which initially has surface exposed vinyl groups, in which thereafter the vinyl groups are chemically modified so as to form different surface exposed functional groups with a greater hydrophilicity and greater biocompatibility than those of the vinyl groups.Type: GrantFiled: December 13, 1999Date of Patent: October 16, 2001Assignee: Renal Tech International LLCInventors: Vadim Davankov, Maria Tsyurupa, Ludmia Pavlova
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Patent number: 6159377Abstract: A method of purification of physiological liquids of organism has the step of passing a physiological liquid through a material which has a size, a shape, and a structure selected so as to remove toxic compounds from the physiological liquid and is composed of a partially chloromethylated porous highly crosslinked styrene or divinylbenzene copolymer which initially have surface exposed chloromethyl groups in which thereafter chlorine is replaced with an element which forms different surface exposed functional groups with a greater hydrophilicity and greater biocompatibility than that of the chloromethyl group.Type: GrantFiled: November 2, 1998Date of Patent: December 12, 2000Assignee: Renal Tech International LLCInventors: Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Dzirda Tur
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Patent number: 6156851Abstract: Purification of physiological liquids of organism is performed by passing a physiological liquid with toxicants removed from a patient through a material which has a size a shape, and a structure selected so as to remove toxic compounds in the molecular range of 300 to 30000 Dalton from the physiological liquid and which is composed of a porous hydrophobic divinylbenzene copolymer which initially has surface exposed vinyl groups in which thereafter the vinyl groups are chemically modified so as to form different surface exposed functional groups with a greater hydrophilicity and greater biocompatibility than those of the vinyl groups.Type: GrantFiled: August 2, 1999Date of Patent: December 5, 2000Assignee: Renal Tech International LLCInventors: Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova
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Patent number: 6153707Abstract: A method of producing a material for purification of physiological liquids of organism has the steps of providing a polymer which has a size, a shape, and a structure selected so as to remove toxic compounds from the physiological liquids, chemically modifying a surface of the polymer so as to provide hydrophilicity and biocompatibility, and performing the modification in a medium with a content of organic substance which is efficient for preventing endotoxins contamination of the polymer.Type: GrantFiled: December 14, 1998Date of Patent: November 28, 2000Assignee: Renal Tech International LLCInventors: Vadim Davankov, Ludmila Pavlova, Maria Tsyurupa
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Patent number: 6136424Abstract: A method of purification of physiological liquids of organism has the step of passing a physiological liquid through a material which has a size, a shape, and a structure selected so as to remove toxic compounds from the physiological liquid and is composed of a partially chloromethylated porous highly crosslinked styrene or divinylbenzene copolymerwhich initially have surface exposed chloromethyl groups in which thereafter chlorine is replaced with an element which forms different surface exposed functional groups with a greater hydrophilicity and greater biocompatibility than that of the chloromethyl group.Type: GrantFiled: February 6, 1998Date of Patent: October 24, 2000Assignee: Renal Tech International, LLCInventors: Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Dzidra Tur
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Patent number: 6133393Abstract: Purification of physiological liquids of organism is performed by passing a physiological liquid with toxicants removed from a patient through a material which has a size a shape, and a structure selected so as to remove toxic compounds in the molecular range of 300 to 30000 Dalton from the physiological liquid and which is composed of a porous hydrophobic divinylbenzene copolymer which initially has surface exposed vinyl groups in which thereafter the vinyl groups are chemically modified so as to form different surface exposed functional groups with a greater hydrophilicity and greater biocompatibility than those of the vinyl groups.Type: GrantFiled: November 2, 1998Date of Patent: October 17, 2000Assignee: Renal Tech International LLCInventors: Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova
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Patent number: 6127311Abstract: For purification of physiological liquids of organism has the step of passing a physiological liquid is passed through a material which has a size, a shape, and a structure selected so as to remove toxic compounds from the physiological liquid and is produced from a partially chloromethylated porous highly crosslinked styrene or divinylbenzene copolymer which initially have surface exposed chloromethyl groups and in which thereafter chlorine is replaced with an element which forms different surface exposed functional groups with a greater hydrophilicity and greater biocompatibility than that of the chloromethyl group.Type: GrantFiled: December 14, 1998Date of Patent: October 3, 2000Assignee: Renal Tech International LLCInventors: Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, D. R. Tur