Patents Assigned to Renascence Therapeutics Limited
  • Therapeutic compositions for intranasal administration of zolpidem
    Patent number: 8916583
    Abstract: The invention provides sprayable aqueous compositions containing zolpidem or single stereoisomer, mixtures of stereoisomers, pharmaceutically acceptable salts or prodrugs thereof, a solubilizing agent, a water soluble polymer with bioadhesive property. When administered intranasally using a spray device, zolpidem is rapidly absorbed with prolonged intranasal residence time and improved bioavailability. The compositions can be applied for the treatment of insomnia-related disorders such as difficulties with sleep initiation or middle of the night awakenings.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: December 23, 2014
    Assignee: Renascence Therapeutics Limited
    Inventors: Yanfeng Wang, Benjamin T. K. Lee, Tony C. Y. Ho, Melvin K. M. Toh
  • THERAPEUTIC COMPOSITIONS FOR INTRANASAL ADMINISTRATION OF ZOLPIDEM
    Publication number: 20130190349
    Abstract: The invention provides sprayable aqueous compositions containing zolpidem or single stereoisomer, mixtures of stereoisomers, pharmaceutically acceptable salts or prodrugs thereof, a solubilizing agent, a water soluble polymer with bioadhesive property. When administered intranasally using a spray device, zolpidem is rapidly absorbed with prolonged intranasal residence time and improved bioavailability. The compositions can be applied for the treatment of insomnia-related disorders such as difficulties with sleep initiation or middle of the night awakenings.
    Type: Application
    Filed: January 22, 2013
    Publication date: July 25, 2013
    Applicant: Renascence Therapeutics Limited
    Inventor: Renascence Therapeutics Limited