Patents Assigned to RENASCIENCE INC.
  • DRUG FOR ENHANCING FIBRINOLYTIC SYSTEM, AND USE THEREFOR
    Publication number: 20230355605
    Abstract: Provided is a drug for enhancing the fibrinolytic system, comprising a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient: wherein R1 is quinolyl, R2 is halogen, and R3 is carboxyl or a group that is biologically equivalent thereto; the active ingredient being administered at a daily dosage of 120 to 300 mg, and the drug being orally administered to a patient with a disease with a clinical condition that is expected to be improved by fibrinolytic enhancement.
    Type: Application
    Filed: May 20, 2021
    Publication date: November 9, 2023
    Applicant: RENASCIENCE INC.
    Inventor: Toshio MIYATA
  • INHIBITOR AGAINST EXPRESSION OF IMMUNE CHECKPOINT MOLECULE
    Publication number: 20220340665
    Abstract: The present invention provides a novel use of a compound having a plasminogen activator inhibitor-1 (PAI-1) inhibitory effect. Specifically, a compound having a PAI-1 inhibitory effect is used as an intranostimulator, an immune checkpoint inhibitor, an inhibitor for exacerbation of tumor cells caused by PD-L1, or an enhancer of immunotherapy for tumors, based on the inhibitory effect of the compound on expression induction of immune checkpoint molecules.
    Type: Application
    Filed: September 30, 2020
    Publication date: October 27, 2022
    Applicant: RENASCIENCE INC.
    Inventors: Kiyoshi ANDO, Takashi YAHATA, Toshio MIYATA