Abstract: A selective laser solidification apparatus including; a powder bed onto which powder layers can be deposited, at least one laser module for generating a plurality of laser beams for solidifying the powder material deposited onto the powder bed, a laser scanner for individually steering each laser beam to solidify separate areas in each powder layer, and a processing unit. A scanning zone for each laser beam is defined by the locations on the powder bed to which the laser beam can be steered by the laser scanner. The laser scanner is arranged such that each scanning zone is less than the total area of powder bed and at least two of the scanning zones overlap. The processing unit is arranged for selecting, for at least one powder layers, which laser beam to use to scan an area of the powder layer located within a region wherein the scanning zones overlap.

Abstract: This invention concerns an additive manufacturing apparatus for building objects by layerwise consolidation of material. The apparatus includes a build chamber containing a working area, a high energy beam for consolidating material deposited in the working area in layers and a flow device for generating a gas flow across at least a part of the working area from a gas inlet to a gas outlet. The gas inlet and gas outlet are arranged to be movable within the build chamber.

Abstract: A method is described for measuring an object using a machine tool and a scanning probe. The scanning probe is driven along a scan path relative to the object whilst the scanning probe acquires probe data describing a series of positions on the surface of the object relative to the scanning probe. The scan path includes at least a first scan path segment for producing probe data that can be analysed to measure the object. The scan path is also arranged to impart a plurality of identifiable probe motions to the scanning probe that can be identified from the acquired probe data alone. Each identifiable probe motion is used to define a time stamp. This allows the probe data to be tied to commanded or nominal positions around the scan path.

Abstract: A percutaneous fluid access apparatus includes a percutaneous fluid access device. The percutaneous fluid access device has a base portion including a subcutaneous portion and at least one port for connection to one or more fluid conduits within a body of a patient. A housing has at least one fluid channel and at least one seal for sealing the at least one fluid channel, and the housing is removably attachable to the base portion. The at least one fluid channel is in fluid communication with the at least one port when the housing is attached to the base portion.

Abstract: A method of putting a feature of interest on an object and an optical inspection system of a non-contact probe mounted on a positioning apparatus in a desired relationship. The method includes: a) identifying a target point of interest on the object to be inspected by arranging the non-contact probe and object at a first relative configuration at which a marker feature, projected by the non-contact probe along a projector axis that is not coaxial with the optical inspection system's optical axis, identifies the target point of interest; and b) subsequently moving the non-contact probe and/or object so as to put them at a second relative configuration at which the target point of interest and optical inspection system are at the desired relationship, in which the positioning apparatus is configured to guide such motion in accordance with the control path.

Abstract: A non-Cartesian coordinate positioning machine that includes an extendable leg assembly for positioning a component such as a measurement probe within a working volume of the machine. The extendable leg assembly includes a first member and a second member which move relative to one another when the extendable leg assembly changes length. The first member including an axial arrangement of magnets forming part of a linear motor for extending and retracting the extendable leg assembly, and at least one resilient member for absorbing at least some of any axial thermal expansion or contraction of the magnets in use.

Abstract: A method of treating a CNS disorder. The method comprises providing a water-soluble histone deacetylase inhibitor, and administering the water-soluble histone deactylase inhibitor directly into a brain via convection enhanced delivery.

Abstract: An encoder apparatus comprising a scale comprising scale features in at least one track which define a series of incremental scale marks and at least one reference mark and a readhead comprising a light source, a diffraction grating, an incremental photodetector and a reference photodetector comprising at least two detector channels. The features defining the at least one reference mark are configured such that the at least one reference mark as resolvable by each of the at least two detector channels comprises a single feature. The optical arrangement of the encoder is such that a non-imaged representation of at least the track in which the at least one reference mark is contained falls onto the detector.

Abstract: A method for determining an attribute of an additive manufacturing apparatus including a plurality of scanners, each scanner including beam steering optics for directing a corresponding radiation beam to a working plane in which material consolidated in layers. The method may include controlling the beam steering optics of a pair of the scanners wherein a first scanner of the pair directs a radiation beam to form a feature in the working plane. The feature is within a field of view of a detector of the second scanner of the pair, the detecting radiation from the working plane is collected by the beam steering optics of the second scanner. Further including recording at least one detector value with the detector of the second scanner for the field of view and determining an attribute of the additive manufacturing apparatus from a comparison of the detector value with an expected detector value.

Abstract: An apparatus and methods for generating geometric data for use in an additive manufacturing process. The apparatus includes a processing unit. The processing unit may be arranged for receiving data defining surface geometry of a plurality of objects to be built together in an additive manufacturing process, providing a user interface that allows a user to define a location of each object within a common build volume and carrying out a slicing operation on at least one of the objects located in the common build volume independently from another one of objects located in the common build volume. The slicing operation determines sections of the at least one object to be built in the additive manufacturing process. In one embodiment, the objects are defined in a hierarchical data structure. Supports for supporting the objects during the build may be defined with reference to a 2-dimensional support cross-section.

Abstract: A method of inspecting an object with a camera probe for capturing an image of an object, the camera probe being movable along a path by a measurement apparatus, at least a part of the camera probe being rotatable about at least one axis. The method includes: a) the measurement apparatus moving the camera probe relative to the object along an inspection path and b) for at least one period as the camera probe moves along the inspection path: turning at least a part of the camera probe about the at least one axis thereby slowing the passage of a feature of interest on the object across the camera probe's field of view; and capturing at least one image of the feature of interest during at least a portion of the turning.

Abstract: An additive manufacturing apparatus for building objects by layerwise consolidation of material. The apparatus includes a build chamber containing a working area, a high energy beam for consolidating material deposited in the working area in layers and a flow device for generating a gas flow across at least a part of the working area from a gas inlet to a gas outlet. The gas inlet and gas outlet are arranged to be movable within the build chamber.

Abstract: A method of forming an optical device comprises applying a laser beam to a target area of the surface so as to selectively heat material of the surface thereby to provide transfer of material due to a surface tension gradient, wherein the surface is such that, when liquid, parts of the surface at higher temperatures have a higher surface tension than adjacent parts of the surface at lower temperatures.

Abstract: A series of nominally identical production workpieces are measured on a workshop coordinate measuring apparatus. They are corrected using correction values generated by comparing coordinate values of a reference workpiece measured on the workshop apparatus with corresponding values derived from external measurements. To reduce the care and skill required, the external measurements are used to determine reference values of a geometric property of a feature of the reference workpiece, rather than coordinate values corresponding directly to those made on the workshop apparatus. Corresponding coordinate values are then generated from knowledge of the perfect form of the feature of the reference workpiece.

Abstract: A rotation detection apparatus, including: a beam source for emitting a beam of polarized light; a decohering arrangement for eliminating or reducing the degree of coherence between first and second independent polarization components of the polarized light to produce a decohered beam of polarized light; a detector for outputting a signal in dependence on the intensity of light incident thereupon, the detector arranged so that the decohered beam of polarized light is incident upon it; a polarizer for location in the path of the decohered beam of polarized light such that rotation of the polarizer relative to the decohered beam of polarized light results in a variation of the intensity of light incident upon the detector from the beam source and a corresponding variation in the signal output from the detector; and a processor for detecting the relative rotation based on the variation of the signal output from the detector.

Abstract: A method of calibrating a scanner of an additive manufacturing apparatus, in which an energy beam is directed with the scanner to consolidate material in a working plane to build up a workpiece in a layer-by-layer manner. The method includes directing the energy beam with the scanner across a test surface in the working plane to form a test pattern, the test pattern having at least one periodic feature, capturing an image of the test pattern, determining from the image a periodic property of the test pattern and determining correction data for control of the scanner based upon the periodic property.

Abstract: A method builds a workpiece using an additive manufacturing process, wherein the workpiece is built up by consolidating material in a layer-by-layer manner. The method includes receiving an initial geometric model defining surface geometry of the workpiece, determining workpiece slices to be consolidated as layers of the workpiece during the additive manufacturing process from the initial geometric model, determining adjusted positions of the workpiece slices adjusted from initial positions of the workpiece slices as determined from the initial geometric model, the determination of the adjusted positions based upon warping of the workpiece expected to occur during or after the additive manufacturing process, and building the workpiece using the additive manufacturing process, wherein the workpiece slices are formed in the adjusted positions.

Abstract: An apparatus and methods for generating geometric data for use in an additive manufacturing process. The apparatus includes a processing unit. The processing unit may be arranged for receiving data defining surface geometry of a plurality of objects to be built together in an additive manufacturing process, providing a user interface that allows a user to define a location of each object within a common build volume and carrying out a slicing operation on at least one of the objects located in the common build volume independently from another one of objects located in the common build volume. The slicing operation determines sections of the at least one object to be built in the additive manufacturing process. In one embodiment, the objects are defined in a hierarchical data structure. Supports for supporting the objects during the build may be defined with reference to a 2-dimensional support cross-section.

Abstract: A method for setting a null position of a scanning probe mounted to the rotatable spindle of a machine tool. This method may be performed as part of a probe qualification process. The method includes setting the null position using probe measurement data collected by the scanning probe when mounted to the spindle. In one embodiment, a stylus tip of the scanning probe may be located in a conical recess whilst the probe measurement data is collected. The set null position is arranged to be away from the rest position of the scanning probe and to substantially coincide with the axis of rotation of the spindle. The need to measure and use a probe offset value in subsequent measurement cycles can thus be avoided.

Abstract: A method of monitoring an additive manufacturing apparatus. The method includes receiving one or more sensor signals from the additive manufacturing apparatus during a build of a workpiece, comparing the one or more sensor signals to a corresponding acceptable process variation of a plurality of acceptable process variations and generating a log based upon the comparisons. Each acceptable process variation of the plurality of acceptable process variations is associated with at least one state of progression of the build of the workpiece and the corresponding acceptable process variation is the acceptable process variation associated with the state of progression of the build when the one or more sensor signals are generated.