Patents Assigned to Renovar
  • Patent number: 10060930
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney disorders. In particular, the present invention relates to the diagnosis, prediction and monitoring of kidney disorders by detection of cytokines, cytokine-related compounds and chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney disorders.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: August 28, 2018
    Assignee: Renovar Incorporated
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Patent number: 9229011
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney disorders. In particular, the present invention relates to the diagnosis, prediction and monitoring of kidney disorders by detection of cytokines, cytokine-related compounds and chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney disorders.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: January 5, 2016
    Assignee: RENOVAR INCORPORATED
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Publication number: 20120208717
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney disorders. In particular, the present invention relates to the diagnosis, prediction and monitoring of kidney disorders by detection of cytokines, cytokine-related compounds and chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney disorders.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 16, 2012
    Applicant: RENOVAR INCORPORATED
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Publication number: 20110236912
    Abstract: The present invention provides systems and methods for characterizing biological markers in the urine of systemic lupus erythematosus (SLE) subjects. In particular, the present invention relates to the detection of cytokines and chemokines in urine of SLE subjects for determining nephritic disease states and kidney damage in SLE subjects and the efficacy of agents and interventions used to treat lupus nephritis.
    Type: Application
    Filed: November 3, 2009
    Publication date: September 29, 2011
    Applicant: Renovar, Inc.
    Inventors: Ganesh Vasudevan, Huaizhong Hu, Stuart Knechtle
  • Publication number: 20090197287
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney disorders. In particular, the present invention relates to the diagnosis, prediction and monitoring of kidney disorders by detection of cytokines, cytokine-related compounds and chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney disorders.
    Type: Application
    Filed: December 8, 2008
    Publication date: August 6, 2009
    Applicant: RENOVAR INCORPORATED
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Patent number: 7531301
    Abstract: The present invention relates to methods of diagnosing and predicting organ transplant rejection. In particular, the present invention relates to the detection and prediction of kidney transplant rejection by detection of CXCR3 and CCL chemokines in urine. The present invention provides improved methods of diagnosing organ rejection and determining the efficacy of anti-rejection drugs.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: May 12, 2009
    Assignee: Renovar
    Inventors: Huaizhong Hu, Alice Puchalaki
  • Patent number: 7476497
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney disorders. In particular, the present invention relates to the diagnosis, prediction and monitoring of kidney disorders by detection of cytokines, cytokine-related compounds and chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney disorders.
    Type: Grant
    Filed: November 21, 2006
    Date of Patent: January 13, 2009
    Assignee: Renovar Incorporated
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Publication number: 20080206794
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney disorders. In particular, the present invention relates to the diagnosis, prediction and monitoring of contrast-induced nephropathy by detection of cytokines, cytokine-related compounds, and chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat contrast-induce nephropathy.
    Type: Application
    Filed: September 17, 2007
    Publication date: August 28, 2008
    Applicant: Renovar Incorporated
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Publication number: 20070249002
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney disorders. In particular, the present invention relates to the diagnosis, prediction and monitoring of kidney disorders by detection of cytokines, cytokine-related compounds and chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney disorders.
    Type: Application
    Filed: November 21, 2006
    Publication date: October 25, 2007
    Applicant: Renovar Incorporated
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Publication number: 20070202085
    Abstract: The present invention is related to transplant rejection. In particular, the present invention relates to determining the functional status of alloreactive T cells and correlating the functional status to in vivo immune responses (e.g., tolerance, rejection, or absence of rejection mediated by T cells). The present invention finds use in basic research, clinical (e.g., transplant) and therapeutic settings.
    Type: Application
    Filed: January 16, 2007
    Publication date: August 30, 2007
    Applicant: Renovar Incorporated
    Inventors: Huaizhong Hu, Stuart Knechtle, Jean Kwun
  • Publication number: 20070134728
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring conditions and disorders associated organ transplantation and organ health. In particular, the present invention relates to the diagnosis, prediction and monitoring of disorders, conditions, and organ status by detection of cytokines, cytokine-related compounds, and chemokines, particularly in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat organ associated disorders and conditions and for maintaining organ health.
    Type: Application
    Filed: October 25, 2006
    Publication date: June 14, 2007
    Applicant: Renovar Incorporated
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Publication number: 20070092898
    Abstract: The present invention relates to methods and kits for the diagnosis and monitoring of hepatitis C virus (HCV) infection and/or Kaposi's sarcoma herpesvirus infection (KSHV) in a subject, as well as other infectious diseases and agents. In particular, the present invention relates to the diagnosis and monitoring of infectious disease through the use of multiple agents directed at a target of interest. For example, the present invention provides for the detection of HCV infection by the detection of antibodies to HCV C22 core, NS 4 (C-10003), NS3 and NS5 antigens, and/or to the diagnosis and monitoring of KSHV infection by detection of antibodies to K8.1, orf73/LNA1 and orf65 antigens in serum. The present invention further relates to methods and kits for assessing the efficacy of agents and interventions used to treat infectious diseases.
    Type: Application
    Filed: August 15, 2006
    Publication date: April 26, 2007
    Applicant: Renovar Incorporated
    Inventor: Huaizhong Hu
  • Patent number: 7138230
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney disorders. In particular, the present invention relates to the diagnosis, prediction and monitoring of kidney disorders by detection of cytokines, cytokine-related compounds and chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney disorders.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: November 21, 2006
    Assignee: Renovar, Inc.
    Inventors: Huaizhong Hu, Stuart Knechtle, Brian D. Aizenstein
  • Patent number: 7138229
    Abstract: The present invention relates to methods of diagnosing, predicting and monitoring kidney diseases, including acute renal failure, renal tubular interstitial disease and glomerulonephritis. In particular, the present invention relates to the detection, prediction and monitoring of kidney diseases by detection of CXCR3 and CCL chemokines in urine. The present invention further relates to methods and compositions for assessing the efficacy of agents and interventions used to treat kidney diseases.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: November 21, 2006
    Assignee: Renovar, Inc.
    Inventors: Huaizhong Hu, Stuart Knechtle
  • Publication number: 20060084184
    Abstract: The present invention provides compositions and methods for detecting analytes in urine. In particular, the present invention provides reagents for accurately detecting antigens in urine through the use of antibody-based assays.
    Type: Application
    Filed: October 19, 2004
    Publication date: April 20, 2006
    Applicant: Renovar Incorporated
    Inventors: Huaizhong Hu, Brian Aizenstein
  • Publication number: 20030228635
    Abstract: The present invention relates to compositions and methods for conducting cell division and proliferation assays (e.g., using flow cytometry), and in particular, to improvements in the effective storage and handling of dyes and reagents used therein.
    Type: Application
    Filed: February 14, 2003
    Publication date: December 11, 2003
    Applicant: Renovar, Inc.
    Inventors: Huaizhong Hu, Alice Puchalski