Patents Assigned to Renovo Limited
  • Promotion of wound contraction
    Publication number: 20080153796
    Abstract: The present invention relates to medicaments and methods for promoting wound contraction. In certain embodiments the invention provides medicaments and methods capable of promoting wound contraction without acceleration of re-epithelialisation.
    Type: Application
    Filed: March 16, 2007
    Publication date: June 26, 2008
    Applicant: RENOVO LIMITED
    Inventors: Nick Occleston, Kerry Nield, Sharon O'Kane, Mark Ferguson
  • Medicaments and methods for wound healing
    Publication number: 20080153795
    Abstract: The present invention relates to the manufacture of medicaments for accelerating the healing of wounds. The invention also relates to methods of treatment for accelerating the healing of wounds. In particular the invention relates to medicaments and methods for the acceleration of healing of skin wounds. The invention relates to wound dressings that are able to provide active agents to a wound, and thereby accelerate healing of the wound, and to formulations such as creams or sprays that may be used to accelerate healing.
    Type: Application
    Filed: March 16, 2007
    Publication date: June 26, 2008
    Applicant: RENOVO LIMITED
    Inventors: Nick Occleston, Kerry Nield, Sharon O'Kane, Mark Ferguson
  • Genetic polymorphism in the Zf9 gene linked to inappropriate scarring or fibrosis
    Patent number: 7332305
    Abstract: The present invention relates to an in vitro method for diagnosing or detecting a predisposition to a condition at least partially characterised by inappropriate fibrosis or scarring (e.g. Dupuytren's Disease). The method comprises examining the ZF9 gene, and regulatory elements thereof, derived from a subject of interest to detect the presence of a genetic poylmorphism or mutation in said gene which is linked with the condition.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: February 19, 2008
    Assignee: Renovo Limited
    Inventors: Mark William James Ferguson, William Ernest Royce Ollier, Ardeshir Bayat
  • Pharmaceutical composition containing inhibitors of interferon-gamma
    Publication number: 20080031879
    Abstract: The present invention provides compositions and methods for promoting the healing of wounds or fibrotic disorders with reduced scarring, comprising inhibitors and inhibiting IFN-?, together with compositions and methods for promoting the healing of chronic wounds, comprising stimulating and stimulators of IFN-?.
    Type: Application
    Filed: July 5, 2007
    Publication date: February 7, 2008
    Applicant: RENOVO LIMITED
    Inventor: Mark Ferguson
  • Use of sex steroid function modulators to treat wounds and fibrotic disorders
    Publication number: 20070185068
    Abstract: The present application relates to the use of compounds that influence the sex hormone system for the treatment of wounds and/or fibrotic disorders. Preferred compounds for use in such treatments are steroid hormones and especially the oestrogens.
    Type: Application
    Filed: April 5, 2007
    Publication date: August 9, 2007
    Applicant: RENOVO LIMITED
    Inventors: Mark Ferguson, Gillian Ashcroft
  • Pharmaceutical composition containing inhibitors of interferon-?
    Patent number: 7220413
    Abstract: The present invention provides compositions and methods for promoting the healing of wounds or fibrotic disorders with reduced scarring, comprising inhibitors and inhibiting IFN-?, together with compositions and methods for promoting the healing of chronic wounds, comprising stimulating and stimulators of IFN-?.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: May 22, 2007
    Assignee: Renovo Limited
    Inventor: Mark William James Ferguson
  • Wound healing and treatment of fibrosis
    Publication number: 20070087969
    Abstract: Compositions for use in the treatment of wounds and fibrosis comprising a therapeutically effective amount of a compound that modulates actin assembly and organization intracellularly and/or extracellularly and a pharmaceutically acceptable vehicle; such a compound promotes the rate of wound healing and also prevents or reduces fibrosis. A preferred compound is gelsolin.
    Type: Application
    Filed: October 2, 2006
    Publication date: April 19, 2007
    Applicant: RENOVO LIMITED
    Inventors: Mark Ferguson, Sharon O'Kane
  • Methods of healing wounds and fibrotic disorders using IL-10
    Patent number: 7052684
    Abstract: The present invention provides IL-10 or a fragment or a partially modified form thereof for use in promoting the healing of wounds and fibrotic disorders with reduced scarring and methods for same.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: May 30, 2006
    Assignee: Renovo Limited
    Inventor: Mark W. J. Ferguson
  • Wound healing
    Publication number: 20050287139
    Abstract: A composition for use in the treatment of wounds to inhibit scar tissue formation during healing is disclosed, comprising an effective activity-inhibiting amount of a growth factor neutralizing agent or agents specific against only fibrotic growth factors together with a pharmaceutically acceptable carrier. The method of preparation of the composition and method of administering the composition to a host suffering from tissue wounding is also disclosed.
    Type: Application
    Filed: June 16, 2005
    Publication date: December 29, 2005
    Applicant: RENOVO LIMITED
    Inventors: Mark Ferguson, David Foreman, Mamta Shah
  • Pharmaceutical composition containing inhibitors of interferon-gamma
    Publication number: 20050158319
    Abstract: The present invention provides compositions and methods for promoting the healing of wounds or fibrotic disorders with reduced scarring, comprising inhibitors and inhibiting IFN-?, together with compositions and methods for promoting the healing of chronic wounds, comprising stimulating and stimulators of IFN-?.
    Type: Application
    Filed: December 17, 2004
    Publication date: July 21, 2005
    Applicant: RENOVO LIMITED
    Inventor: Mark Ferguson
  • Pharmaceutical composition
    Patent number: 6900181
    Abstract: The present invention concerns analogues of M6P for use in promoting the healing of wounds or fibrotic disorders with reduced scarring, together with methods for doing same.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: May 31, 2005
    Assignee: Renovo Limited
    Inventors: Mark W. J. Ferguson, Sarah G. Jones, Sally Freeman
  • Method for quantifying TGF-?
    Patent number: 6855505
    Abstract: The present invention relates to a method for quantifying the amount of active transforming growth factor beta (TGF-?) in biological samples. In particular the method comprising incubating cryosections of a tissue with cells which contain a TGF-? responsive expression vector having a structural region encoding an indicator protein and measuring the amount of said indicator protein expressed from the cells.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: February 15, 2005
    Assignee: Renovo Limited
    Inventors: Mark W. J. Ferguson, Georg Brunner
  • Pharmaceutical composition containing inhibitors of interferon-gamma
    Publication number: 20040208871
    Abstract: The present invention provides compositions and methods for promoting the healing of wounds or fibrotic disorders with reduced scarring, comprising inhibitors and inhibiting IFN-&ggr;, together with compositions and methods for promoting the healing of chronic wounds, comprising stimulating and stimulators of IFN-&ggr;.
    Type: Application
    Filed: November 28, 2003
    Publication date: October 21, 2004
    Applicant: RENOVO LIMITED
    Inventor: Mark William James Ferguson
  • Use of sex steroid function modulators to treat wounds and fibrotic disorders
    Publication number: 20040132701
    Abstract: The present application relates to the use of compounds that influence the sex hormone system for the treatment of wounds and/or fibrotic disorders. Preferred compounds for use in such treatments are steroid hormones and especially the oestrogens.
    Type: Application
    Filed: December 22, 2003
    Publication date: July 8, 2004
    Applicant: RENOVO LIMITED
    Inventors: Mark WJ Ferguson, Gillian S. Ashcroft
  • Pharmaceutical composition
    Publication number: 20040072763
    Abstract: The present invention concerns analogues of M6P for use in promoting the healing of wounds or fibrotic disorders with reduced scarring, together with methods for doing same.
    Type: Application
    Filed: March 18, 2003
    Publication date: April 15, 2004
    Applicant: RENOVO LIMITED
    Inventors: Mark W.J. Ferguson, Sarah G. Jones, Sally Freeman
  • Pharmaceutical composition containing an activin or inhibin stimulator
    Publication number: 20040052795
    Abstract: The present invention concerns stimulators of Activin and/or Inhibin for use in promoting the healing of wounds and fibrotic disorders with reduced scarring, together with medicaments and methods for promoting the healing of wounds and fibrotic disorders with reduced scarring.
    Type: Application
    Filed: September 5, 2003
    Publication date: March 18, 2004
    Applicant: RENOVO LIMITED
    Inventor: Mark W.J. Ferguson
  • Use of sex steroids function modulators to treat wounds and fibrotic disorders
    Patent number: 6696433
    Abstract: The present application relates to the use of compounds that influence the sex hormone system for the treatment of wounds and/or fibrotic disorders. Preferred compounds for use in such treatments are steroid hormones and especially the oestrogens.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: February 24, 2004
    Assignee: Renovo Limited
    Inventors: Mark W J Ferguson, Gillian S Ashcroft
  • Method for quantifying TGF-beta
    Publication number: 20030129668
    Abstract: The present invention relates to a method for quantifying the amount of active transforming growth factor beta (TGF-&bgr;) in biological samples. In particular the method comprising incubating cryosections of a tissue with cells which contain a TGF-&bgr; responsive expression vector having a structural region encoding an indicator protein and measuring the amount of said indicator protein expressed from the cells.
    Type: Application
    Filed: November 12, 2002
    Publication date: July 10, 2003
    Applicant: RENOVO LIMITED
    Inventors: Mark W.J. Ferguson, Georg Brunner
  • Pharmaceutical composition
    Patent number: 6566339
    Abstract: The present invention concerns analogues of M6P for use in promoting the healing of wounds or fibrotic disorders with reduced scarring, together with methods for doing same.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: May 20, 2003
    Assignee: Renovo Limited
    Inventors: Mark William James Ferguson, Sarah Glenys Moore, Sally Freeman
  • Wound healing
    Publication number: 20020187149
    Abstract: A composition for use in the treatment of wounds to inhibit scar tissue formation during healing is disclosed, comprising an effective activity-inhibiting amount of a growth factor neutralising agent or agents specific against only fibrotic growth factors together with a pharmaceutically acceptable carrier. The method of preparation of said composition and method of administering the composition to a host suffering from tissue wounding is also disclosed.
    Type: Application
    Filed: April 8, 2002
    Publication date: December 12, 2002
    Applicant: RENOVO LIMITED
    Inventors: Mark William James Ferguson, David Michael Foreman, Mamta Shah