Patents Assigned to RESDEVCO RESEARCH AND DEVELOPMENT CO. LTD.
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Patent number: 11426361Abstract: A method for treatment of irritation or damage to corneal or conjunctival epithelial cells, particularly for irritation or damage to corneal or conjunctival epithelial cells due to severe Sjögren's syndrome, comprising applying topically to an affected eye an aqueous solution of glycerol characterized by a glycerol concentration of >1% (w/v), most preferably 2.5% (w/v). The method is effective even in the case of very low tear formation, and its effectiveness cannot be explained by the known humectant effect of glycerol.Type: GrantFiled: March 3, 2021Date of Patent: August 30, 2022Assignee: Resdevco Research and Development Co. Ltd.Inventor: Shabtay Dikstein
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Patent number: 11033513Abstract: A method for treatment of irritation or damage to conical or conjunctival epithelial cells, particularly for irritation or damage to corneal or conjunctival epithelial cells due to severe Sjögren's syndrome, by applying topically to an affected eye an aqueous solution of glycerol characterized by a glycerol concentration of >1% (w/v), most preferably 2.5% (w/v). The method is effective even in the case of very low tear formation, and its effectiveness cannot be explained by the known humectant effect of glycerol.Type: GrantFiled: September 4, 2019Date of Patent: June 15, 2021Assignee: Resdevco Research and Development Co. Ltd.Inventor: Shabtay Dikstein
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Patent number: 10660961Abstract: The present invention provides a method of treatment of irritation of skin or mucous cells. The method comprises applying topically a composition comprising a combination of: xylitol, myonisotiol or mannitol or any combination of these; glycerol and/or urea; water; in the absence of any oil in water or wax in water emulsion.Type: GrantFiled: August 28, 2017Date of Patent: May 26, 2020Assignee: RESDEVCO RESEARCH AND DEVELOPMENT CO., LTD.Inventor: Shabtay Dikstein
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Publication number: 20170354735Abstract: The present invention provides a method of treatment of irritation of skin or mucous cells. The method comprises applying topically a composition comprising a combination of: xylitol, myonisotiol or mannitol or any combination of these; glycerol and/or urea; water; in the absence of any oil in water or wax in water emulsion.Type: ApplicationFiled: August 28, 2017Publication date: December 14, 2017Applicant: RESDEVCO RESEARCH AND DEVELOPMENT CO. LTD.Inventor: Shabtay DIKSTEIN
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Publication number: 20170354624Abstract: A topical pharmaceutical or composition for prevention and treatment of irritation to skin cells. The composition comprises an aqueous solution of xylitol and glycerol. In a preferred embodiment, the composition comprises 5% (w/w) xylitol, 5% (w/w) glycerol, a viscosity-enhancing agent, base to bring to the pH to 4.9, and optionally, a pharmaceutically active agent.Type: ApplicationFiled: August 28, 2017Publication date: December 14, 2017Applicant: RESDEVCO RESEARCH AND DEVELOPMENT CO. LTD.Inventor: Shabtay DIKSTEIN
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Publication number: 20170021023Abstract: A topical pharmaceutical or cosmetic composition for treatment of irritation of mucous cells such as mucosal cells of the eye, nose, and vagina is disclosed. The composition comprises an aqueous solution of at least one polyol selected from the group consisting of xylitol, myoinositol and mannitol and at least one substance selected from the group consisting of glycerol and urea. The composition contains less than 0.01% inorganic salt and is free of any oil-in-water or wax-in-water emulsion. In particularly preferred embodiments, the composition comprises an aqueous solution containing 1.5-5% (w/v) xylitol and 0.9-2.0% (w/v) glycerol.Type: ApplicationFiled: October 6, 2016Publication date: January 26, 2017Applicant: RESDEVCO RESEARCH AND DEVELOPMENT CO. LTD.Inventor: Shabtay DIKSTEIN
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Publication number: 20160331764Abstract: A composition for delivering cholecalciferol to skin and/or mucous membranes via topical application. The composition comprises xylitol and cholecalciferol in emulsion. Optionally, the composition may include additional components such as glycerol, polyethylene glycol, propylene glycol, pharmaceutical agents, stabilizers, acids, bases, buffers, antioxidants, emulsifiers, suspending agents, and preservatives. Methods of preparation of the composition and of using it as a topical treatment for delivery of cholecalciferol to the skin and/or mucous membranes are also disclosed.Type: ApplicationFiled: January 25, 2015Publication date: November 17, 2016Applicant: RESDEVCO RESEARCH AND DEVELOPMENT CO. LTD.Inventor: Shabtay DIKSTEIN
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Patent number: 8912166Abstract: An ophthalmic preparation and method, usable to treat conjunctivochalasis. The ophthalmic preparation comprises an aqueous solution of glycerol. The preparation may also include additional components including high molecular weight polymers for viscosity control and pharmacologically active substances. The method includes administering an ophthalmic preparation including an aqueous solution of glycerol to a patient.Type: GrantFiled: November 5, 2013Date of Patent: December 16, 2014Assignee: Resdevco Research and Development Co. Ltd.Inventor: Shabtay Dikstein
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Publication number: 20140057983Abstract: An ophthalmic preparation and method, usable to treat conjunctivochalasis. The ophthalmic preparation comprises an aqueous solution of glycerol. The preparation may also include additional components including high molecular weight polymers for viscosity control and pharmacologically active substances. The method includes administering an ophthalmic preparation including an aqueous solution of glycerol to a patient.Type: ApplicationFiled: November 5, 2013Publication date: February 27, 2014Applicant: RESDEVCO RESEARCH AND DEVELOPMENT CO. LTD.Inventor: Shabtay DIKSTEIN
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Publication number: 20080207771Abstract: The present invention provides new topical pharmaceutical or cosmetic compositions for the prevention and treatment of irritation of mucous cells, or skin cells, comprising a combination of: xylitol, myoinositol or mannitol or any combination of these; glycerol and/or urea; water; in the absence of any oil in water or wax in water emulsion.Type: ApplicationFiled: May 7, 2006Publication date: August 28, 2008Applicant: RESDEVCO RESEARCH AND DEVELOPMENT CO. LTD.Inventor: Shabtay Dikstein
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Patent number: 5037010Abstract: A dispensing container for a viscous substance comprising a sleeve defining an axis of rotation and having a pair of ends arranged at first and second locations along the axis, the sleeve further defining a helical travel path on an inward facing surface thereof. A dispensing member mounted in association with one of the pair of ends of the sleeve, and, a piston head mounted within the sleeve and defining an outward facing peripheral surface operative to cooperate with the helical travel path and further defining with the dispensing member and a portion of the sleeve extending therebetween a storage volume for the viscous substance. The piston head travels along the axis of rotation when undergoing rotation thereabout relative to the sleeve, a linkage apparatus is integrally formed with the piston head and defining an end portion associated with a predetermined portion of the sleeve.Type: GrantFiled: July 11, 1989Date of Patent: August 6, 1991Assignees: Resdevco Research & Development Co. Ltd., Lageen Box & Can Factory Ltd.Inventor: Shabtai Dikstein