Abstract: A scintigraphy guided system for stereotaxic localization of breast carcinomas, used in conjunction with a scintillation detection device, of a patient who has been injected with a radioactive substance which preferentially accumulates in carcinomas. The system includes a table, a pair of fenestrated paddles, and a guide means. The table has a top surface, upon which the patient lies in a prone position, and at least one opening through which the patient's breast being examined will pendulously protrude therethrough. A pair of fenestrated paddles are positioned under the bottom surface of the table in the vicinity of the opening, and are moveable relative to each other to compress the patient's breast therebetween. The guide is positioned under the table in the vicinity of the opening. The guide has plurality of moveable sighting guides, each moveable along one of three orthogonal axes, and each sighting guide having a radioactive sighting line located thereon.

Abstract: The invention is a total knee endoprosthesis with a fixed flexion-extension axis throughout all degrees of flexion and extension of the knee. The endoprosthesis has a femoral component with spaced apart medial and lateral condyle portions which slidably seat on a tibial implant portion. The fixed flexion-extension axis is directed inferiorly and posteriorly from the medial condyle portion to the lateral condyle portion and is offset from both the transverse and coronal planes equally by 3.0 to 3.8 degrees. A longitudinal axis through the tibia allows the tibia to rotate nonorthogonally and anteriorly of the flexion-extension axis. A patellar groove which is perpendicular to the flexion-extension axis. In the patellar groove slides an optional patellar component or the natural patella.

Abstract: A composition for neonatal ophthalmic prophylactic and a method of applying the composition. The composition comprises an aqueous solution of povidone-iodine having a concentration ranging from 5 percent to 0.1 percent. The composition of this invention prevents conjunctivitis caused by gonococus and other bacteria including chlamydia, as well as viruses and fungi.

Abstract: The invention is a single use transcervical catheterization cannula retained by forceps for use with a catheter wire and radiopaque dye fluid. The cannula has a flexible shaft portion, an acorn to seat with the cervical canal, a fluid/catheter wire access port, and a handle member which is rotatably and axially movable on the shaft of the cannula but which can be locked at a desired position on the shaft of the cannula. A notch on a wing of the handle member engages with forceps to hold the cannula in liquid tight contact with the cervical canal. Extending beyond the end of the acorn is a curved tip, through whose open end the catheter wire is extended.

Abstract: The invention is a total knee endoprosthesis with a fixed flexion-extension xis throughout all degrees of flexion and extension of the knee. The endoprosthesis has a femoral component with spaced apart medial and lateral condyle portions which slidably seat on a tibial implant portion. The fixed flexion-extension axis is directed inferiorly and posteriorly from the medial condyle portion to the lateral condyle portion and is offset from both the transverse and coronal planes equally by 3.0 to 3.8 degrees. A longitudinal axis through the tibia allows the tibia to rotate nonorthogonally and anteriorly of the flexion-extension axis. A patellar groove which is perpendicular to the flexion-extension axis. In the patellar groove slides an optional patellar component or the natural patella.

Abstract: An apparatus and method for in vitro bleeding time determination. Blood is placed in a tube having a window covered with a clot promoting material having a slit. The time required before blood stops flowing through the slit is recorded, and is the bleeding time. It is preferred that the clot-promoting material be nylon fabric impregnated with collagen and blood clot promoting proteins.

Abstract: A method for the diagnosis and treatment of infertile women, utilizing norgical, transcervical uterine lavage to recover ova for the purpose of analysis, morphologic assessment, and treatment.

Abstract: A method of forming a surgical mesh material to be used in conjunction with donor bone in reconstructive surgery. A first corporeal model is made of the defect in the bone using computer tomographic techniques. The computer drives a sculpting tool. A second corporeal model is made of missing bone. Surgical mesh is shaped using the second corporeal model as a template. The shaped surgical mesh can be implanted in the patient.

Abstract: A kit and a method for detecting the presence of an antibody inhibiting HIV (the AIDS virus) reverse transcriptase. The amount of antibody inhibiting HIV reverse transcriptase present in the body fluids of a patient known to be immunopositive for HIV gives the clinician a means to form a prognosis for each individual case.

Abstract: A device for enabling substantially-anatomic reduction of a posteriorly uable pelvic disruption, as of a fracture or dislocation of the posterior pelvis. The device is adapted to enable secure fixation thereof to the posterior pelvic disruption. It is further adapted to enable fine adjustment of the alignment and fit of the disrupted surfaces, operable from a position externally of the patient's body, and to retain the united positions of the disrupted surfaces, for substantially-anatomically reducing the posteriorly unstable pelvic disruption. The device includes a plurality of tapper threaded pins, each adapted to be tapped into the outer cortices of the posterior pelvic bone at a location proximate the site of the posterior pelvic disruption. The device further includes a frame, adapted to enable the tapper threaded pins to be connected thereto for interconnection thereof, and mechanisms adapted to enable externally operable fine adjustment of the frame in a plurality of planes.

Abstract: A method and apparatus for the controlled simulation of respiratory gas exchange as it takes place in mammals, for the primary purpose of calibrating and checking the performance of laboratory and clinical test equipment systems. The method and apparatus can reproduce any range of respiratory performance by pumping and mixing atmospheric air with a gas mixture of carbon dioxide and nitrogen. This invention provides an accurate, economical and rapid apparatus for on-line calibration of analytical respiratory test systems.

Abstract: A method and apparatus for the controlled simulation of respiratory gas exchange as it takes place in mammals, for the primary purpose of calibrating and checking the performance of laboratory and clinical test equipment systems. The method and apparatus can reproduce any range of respiratory performance by pumping and mixing atmospheric air with a gas mixture of carbon dioxide and nitrogen. The subject matter of the disclosure provides an accurate, economical and rapid means of on-line calibration of analytical respiratory test systems.

Abstract: A device for enabling testing of a person's physical condition, by enabling easurement of the energy expended by the person to be tested thereby, in manually maintaining rotation of a flywheel in a stationary bicycle, against resistance applied to the flywheel, for use in determining the efficiency of the person's body in using energy, as an indication of such person's physical condition.The device is adapted to overcome inertia of the flywheel, from rest to a selected speed of rotation thereof, in an efficient and effective manner, prior to the onset of the test. Upon the onset of the test, with inertia in the flywheel having been non-manually overcome, the person to be tested is to manually maintain rotation of the flywheel, against resistance applied thereto, by manually rotating pedals operably connected to the flywheel.The device includes a non-manual inertia overcoming mechanism.

Abstract: This invention relates a simplified and reliable process for the detection and measurement of viral specific immunoglobulins such as IgG, IgM and IgE wherein relatively large-diameter plastic beads, e.g., 1/4", diameter polystyrene balls with a specular finish, are used as the solid matrix upon which a high concentration of standard cells are first grown or cultured. The cells are then infected with a particular virus to express a high concentration of unpurified viral antigen(s), and are then fixed to preserve the viral antigen(s) concentration. The resulting fixed plastic beads (PB) are washed (to remove fixing agent) and then employed as the basis of the detection of specific immunoglobulins in the patient's serum. The detection process involves simply incubating a measured dilution of patient serum with each PB whereby the various specific immunoglobulins in the patient serum will attach to the viral antigen(s) on the PB. The specific immunoglobulins (e.g.

Abstract: This invention relates to a highly accurate, rapid and simple estimation of thyroxine (T.sub.4) directly from blood serum and also relates to the accurate measurement of triiodo-L-thyronine (T.sub.3) directly from blood serum. More specifically, the invention relates to a rapid, specific and reliable radioimmunoassay (RIA) technique for measurement of both T.sub.4 and T.sub.3 in unextracted serum. The method requires very small amounts of serum, e.g., 25 microliters (.mu.l) to measure T.sub.4 concentration in nearly all specimens representing clinical states of eu-, hypo- and hyperthyroidism, and 250 .mu.l to measure T.sub.3 concentrations in specimens representing most clinical states.