Abstract: A method for high resolution photoacoustic imaging in scattering media using structured illumination may include illuminating a sample of an absorption object with structured illumination, including illuminating the sample with multiple different speckle patterns at different times. The method may also include detecting multiple photoacoustic signals generated by the absorption object in response to illumination with the different speckle patterns to generate multiple photoacoustic responses. The method may also include reconstructing an absorber distribution of the absorption object by exploiting joint sparsity of sound sources in the plurality of photoacoustic responses.
Type:
Grant
Filed:
September 28, 2017
Date of Patent:
February 4, 2020
Assignees:
The Regents of the University of Colorado, a body corporate, Research Center for Non Destructive Testing GmbH, University of Innsbruck
Inventors:
Todd W. Murray, Peter Burgholzer, Markus Haltmeier
Abstract: A method for laser-optical detection of a surface movement of a sample (1) is specified, whereby a first laser reference beam (10) is superimposed with a first laser measurement beam (12) directed onto the sample (1) and reflected by the latter in a first photorefractive/electro-optical element (4). In addition, a second reference beam (11) identical to the first reference beam (10) is superimposed with a second measurement beam (13) identical to the first measurement beam (12) in a second photorefractive/electro-optical element (5). Mutually inverse voltages are applied to the two photorefractive/electro-optical elements (4, 5). The light emerging from the photorefractive/electro-optical elements (4, 5) is converted into electric signals which are subtracted from one another prior to the signal evaluation. Also specified is an arrangement for implementing said method.
Type:
Grant
Filed:
October 30, 2013
Date of Patent:
May 16, 2017
Assignees:
Fill Gesellschaft m.b.H., Research Center for Non Destructive Testing GmbH
Abstract: A method and a device for monitoring a property of a coating of a solid dosage form during a coating process forming the coating of the solid dosage form are provided. The device comprises a coating apparatus configured for forming the coating on the solid dosage form, and a monitoring apparatus configured for monitoring the property of the coating of the solid dosage form in process, wherein at least a part of the monitoring apparatus is located so as to have insight in an interior of the coating apparatus, the interior accommodating the solid dosage form to be coated and a precursor for forming the coating, and wherein the monitoring apparatus is configured for monitoring the property of the coating of the solid dosage form simultaneously with and during a coating process using low coherence interferometry.
Type:
Grant
Filed:
April 29, 2014
Date of Patent:
May 16, 2017
Assignees:
Research Center Pharmaceutical Engineering GmbH, Research Center for Non Destructive Testing GmbH
Inventors:
Daniel Markl, Guenther Hannesschlaeger, Michael Leitner, Stephan Sacher, Daniel Koller, Johannes Khinast
Abstract: A method for laser-optical detection of a surface movement of a sample (1) is specified, whereby a first laser reference beam (10) is superimposed with a first laser measurement beam (12) directed onto the sample (1) and reflected by the latter in a first photorefractive/electro-optical element (4). In addition, a second reference beam (11) identical to the first reference beam (10) is superimposed with a second measurement beam (13) identical to the first measurement beam (12) in a second photorefractive/electro-optical element (5). Mutually inverse voltages are applied to the two photorefractive/electro-optical elements (4, 5). The light emerging from the photorefractive/electro-optical elements (4, 5) is converted into electric signals which are subtracted from one another prior to the signal evaluation. Also specified is an arrangement for implementing said method.
Type:
Application
Filed:
October 30, 2013
Publication date:
October 22, 2015
Applicants:
Research Center for Non Destructive Testing GmbH, Fill Gesellschaft m.b.H.
Abstract: A method and a device for monitoring a property of a coating of a solid dosage form during a coating process forming the coating of the solid dosage form are provided. The device comprises a coating apparatus configured for forming the coating on the solid dosage form, and a monitoring apparatus configured for monitoring the property of the coating of the solid dosage form in process, wherein at least a part of the monitoring apparatus is located so as to have insight in an interior of the coating apparatus, the interior accommodating the solid dosage form to be coated and a precursor for forming the coating, and wherein the monitoring apparatus is configured for monitoring the property of the coating of the solid dosage form simultaneously with and during a coating process using low coherence interferometry.
Type:
Application
Filed:
April 29, 2014
Publication date:
October 30, 2014
Applicants:
Research Center Pharmaceutical Engineering GmbH, Research Center for Non Destructive Testing GmbH
Inventors:
Daniel Markl, Guenther Hannesschlaeger, Michael Leitner, Stephan Sacher, Daniel Koller, Johannes Khinast