Patents Assigned to Research Cooperation Foundation of Yeungnam University
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Publication number: 20220105047Abstract: The present invention relates to a microcapsule composition in which polydopamine-coated calcium carbonate microspheres are encapsulated by forming an alginate gel on the surface of a spheroid conjugated thereto, and a method of preparing the same, and it is confirmed that according to the method of preparing the microcapsule, the drug or physiologically active material was individually microencapsulated by gradually forming an alginate gel on the surface of the spheroid containing the drug or physiologically active material, a drug or a bioactive material is placed in the center of a capsule in a very simple way, and a capsule of a very small size can be manufactured in a short time compared to the conventional encapsulation method by adjusting the size of the capsule.Type: ApplicationFiled: August 7, 2019Publication date: April 7, 2022Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Jee-Heon JEONG, Thanh Tung PHAM
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Publication number: 20220096425Abstract: The present invention relates to an antiviral composition and a screening method thereof for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that occurred in Wuhan, China in 2019. An extract from leaves or unfertilized female flowers of Cannabis sativa L. or its fraction, and the cannabinoids (CBDs) molecules isolated from it have high binding strength and stability to SARS-CoV-2 Mpro, thereby inhibiting its action as the main protease, to provide a useful lead molecule that can be used alone or in combination with other drugs to treat SARS-CoV-2.Type: ApplicationFiled: September 3, 2021Publication date: March 31, 2022Applicants: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Jintae LEE, Jungyeob HAM, Taejung KIM
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Publication number: 20220023271Abstract: The present invention relates to a composition for preventing or treating cellular senescence-associated diseases comprising zotarolimus as an active ingredient, and in more detail, it was confirmed that zotarolimus exhibits a senomorphics effect of restoring the function and morphology of fibroblasts, umbilical vascular endothelial cells, renal tubular cells and retinal pigmented epithelial cells, in which senescence is induced and exhibits an effect of improving tissue fibrosis induced by cellular aging through the senomorphics effect and thus the composition comprising zotarolimus as an active ingredient can be provided as a composition for treating cellular senescence-associated diseases.Type: ApplicationFiled: October 11, 2019Publication date: January 27, 2022Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Jae-Ryong KIM, Eok-Cheon KIM, Kyong-Jin JUNG, You Lim SON
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Publication number: 20220023309Abstract: The present invention relates to a composition for preventing or treating cellular senescence-associated diseases comprising homoharringtonine as an active ingredient, and it was confirmed that the composition comprising homoharringtonine as an active ingredient exhibits a senolytics effect of selectively killing aging-induced fibroblasts and renal tubular cells, whereas aging-induced vascular endothelial cells and epithelial melanocytes and retinal pigmented epithelial cells, and exhibits a senomorphics effect of restoring the function and morphology of cells, and thus the homoharringtonine acts differently depending on the type of cells to effectively prevent or treat senile eye disease, tissue fibrosis disease, atherosclerosis, osteoarthritis, degenerative brain disease, chronic skin damage, obesity and diabetes caused by cellular aging and can be provided as a composition for whitening skin and life extension.Type: ApplicationFiled: October 11, 2019Publication date: January 27, 2022Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Jae-Ryong KIM, Eok-Cheon KIM, Kyong-Jin JUNG, Bum-Ho BIN, You Lim SON
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Publication number: 20220016043Abstract: The present application relates to a method for manufacturing a red blood cell-shaped nanostructure and a red blood cell-shaped nanostructure manufactured by the manufacturing method thereof. More specifically, the present application relates to a method for manufacturing a red blood cell-shaped nanostructure using a multi-fluid electrospray method including multiple nozzles, and a red blood cell-shaped nanostructure manufactured by the manufacturing method thereof.Type: ApplicationFiled: November 25, 2019Publication date: January 20, 2022Applicants: University-Industry Foundation, Yonsei University, Research Cooperation Foundation of Yeungnam UniversityInventors: Jeong Hoon BYEON, Jung Ho HWANG, Dae Hoon PARK, Kang Sik NAM
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Publication number: 20220008377Abstract: The present invention relates to a composition for preventing or treating cellular senescence-associated diseases comprising salinomycin as an active ingredient, which acts differently depending on the type of senescent cells, and it was confirmed that salinomycin exhibits a senomorphics effect of restoring the function and morphology of fibroblasts and vascular endothelial cells in which senescence is induced and exhibits a senolytics effect of selectively killing aging-induced retinal pigmented epithelial cells, and exhibits a senomorphics effect of restoring the function and morphology of cells, and thus the salinomycin acts differently depending on the type of cells to effectively prevent or treat senile eye disease, tissue fibrosis disease, atherosclerosis, osteoarthritis, degenerative brain disease, chronic skin damage, obesity and diabetes caused by cellular aging and can be provided as a composition for life extension.Type: ApplicationFiled: October 11, 2019Publication date: January 13, 2022Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Jae-Ryong KIM, Eok-Cheon KIM, Kyong-Jin JUNG, You Lim SON
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Publication number: 20210315957Abstract: A pharmaceutical composition and a health functional food composition for preventing, treating, or improving muscular diseases have licorice extract or a fraction thereof, or a compound isolated therefrom or a pharmaceutically acceptable salt thereof, as an active ingredient. The licorice extract or a fraction thereof, the compound or salt thereof induce the myoblasts proliferation and promote the differentiation into myotubes, and since the licorice extract or a fraction thereof, the compound or salt thereof has an excellent effect on regenerating damaged muscles, various muscle diseases are effectively prevented, improved or treated using the composition.Type: ApplicationFiled: June 17, 2020Publication date: October 14, 2021Applicants: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY, KOREA INSTITUTE OF ORIENTAL MEDICINE, DAEGU CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATIONInventors: Inho CHOI, Eun Ju LEE, So-young PARK, Yong-Ho LEE, Jin Yeul MA, Won-Kyung CHO, Hye Jin YANG
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Patent number: 11052429Abstract: Disclosed herein is a particle separation apparatus. The particle separation apparatus includes: a bioreactor; a first flow path through which the sludge is discharged from the bioreactor; a first filter including a first mesh separating the granular microorganisms contained in the sludge according to size; a second flow path into which an effluent having passed through the first filter flows; a third flow path connected to the second flow path to discharge the effluent outside; a fourth flow path connected to one side of the second flow path and mounted on a surface of the first filter connected to a surface of the first filter with the second flow path mounted thereon; a fifth flow path through which the effluent having been discharged from the fourth flow path and passed through the first filter flows into the bioreactor; and a first pump creating a flow of the effluent.Type: GrantFiled: July 17, 2017Date of Patent: July 6, 2021Assignee: Research Cooperation Foundation of Yeungnam UniversityInventors: Jin Young Jung, Byeong Jun Lee
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Publication number: 20210028074Abstract: Disclosed in the present specification are an apparatus and a method capable of quickly verifying a plurality of micro LEDs. An LED verification substrate according to the present specification is a micro LED verification substrate having a plurality of verification chips, wherein each verification chip can comprise: a first contact deposited on the upper side of a lower substrate; a first passivation layer deposited on the upper side of the first contact; a second contact deposited on the upper side of the first passivation layer; a second passivation layer deposited on the upper side of the second contact; a first bump electrically connected to the first contact and protruding above the upper surface of the second passivation layer; and a second bump electrically connected to the second contact and protruding above the upper surface of the second passivation layer.Type: ApplicationFiled: March 19, 2019Publication date: January 28, 2021Applicant: Research Cooperation Foundation of Yeungnam UniversityInventors: Si Hyun Park, Young Woong Lee
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Patent number: 10899915Abstract: Disclosed is a wax-based thermoplastic organic binder composition consisting of: 50 to 94 wt % of a wax mixture comprising paraffin wax and microcrystalline wax; 3 to 35 wt % of a polyolefin copolymer having a carbonyl group as a backbone polymer; and 3 to 15 wt % of a process control agent.Type: GrantFiled: November 7, 2016Date of Patent: January 26, 2021Assignee: Research Cooperation Foundation of Yeungnam UniversityInventor: Kwan Hee Han
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Patent number: 10881854Abstract: Provided is a respiratory muscle strengthening device, in which an inhalation start signal is generated correspondingly at an inhalation start time when a patient inhales air or an exhalation start signal is generated correspondingly at an exhalation start time when the patient exhales air, an electric signal according to the inhalation start signal or the exhalation start signal is transmitted to an electric muscle stimulator via a communication unit, a muscle pad installed on respiratory muscles of the patient enables smooth breathing motion by stimulating the respiratory muscles based on a signal transmitted from the electric muscle stimulator, and a receptor pad is provided to the respiratory muscles such that an alarm of determining whether electric stimulation is normally applied via the state of the respiratory muscles detected through the receptor pad is output, thereby securing reliability of a device.Type: GrantFiled: June 20, 2017Date of Patent: January 5, 2021Assignee: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Su Min Son, Eun Yong Choi, Joon Ha Lee, So Young Kwak
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Patent number: 10864300Abstract: Disclosed is a method for preparing a bilayer scaffold through single process comprising: preparing a first polymer aqueous solution; adding a second polymer into the first polymer aqueous solution and stirring a reactant; adding a surfactant into the stirred reactant and stirring the reactant at high temperature and high speed; freeze-drying the stirred reactant thereby obtaining a sponge; dipping the sponge in a cross-linking agent thereby rendering be cross-linked; and freeze-drying the cross-linked reactant.Type: GrantFiled: July 16, 2013Date of Patent: December 15, 2020Assignee: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Sung Soo Han, Soon Mo Choi, Deep Ti Singh
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Patent number: 10786460Abstract: The present invention relates to a self-assembly preparation method of a nanocomposite material, and more particularly, relates to a self-assembly preparation method of a nanocomposite material comprising steps of: spraying a drug-containing solution onto metal aerosol nanoparticles to form a drug layer on the metal aerosol nanoparticles; and spraying a polymer-containing solution onto the metal aerosol nanoparticles, on which the drug layer is formed, to form a polymer layer on the drug layer, whereby since the method involves no liquid chemical process upon producing the metal aerosol nanoparticles, the processes are simple and can be performed even at a low temperature to suppress deformation of an organic or a drug, and the release rate of the drug, or the like can be easily controlled through metal types of metal aerosol nanoparticles, modification, and the like.Type: GrantFiled: November 8, 2016Date of Patent: September 29, 2020Assignee: Research Cooperation Foundation of Yeungnam UniversityInventor: Jeong Hoon Byeon
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Patent number: 10785078Abstract: A method for signal modulation in a filter bank multi-carrier system is provided. A modulation method according to one embodiment of the present disclosure includes generating a plurality of different candidate transmission signals by modulating a complex symbol vector including a plurality of complex symbols in a discrete Fourier transform (DFT) spread filter bank multi-carrier (FBMC)/offset quadrature amplitude modulation (OQAM) scheme and selecting a candidate transmission signal having a lowest peak power or peak-to-average power ratio (PAPR) as a transmission signal, wherein the generating of the plurality of candidate transmission signals comprises applying a different phase offset to the complex symbol vector according to a candidate transmission signal to be generated.Type: GrantFiled: August 22, 2019Date of Patent: September 22, 2020Assignee: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Kwonhue Choi, Dongjun Na
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Patent number: 10773219Abstract: The present invention relates to: a polymer composition for preparing a hydrophilic separation membrane, containing sulfonated inorganic particles, preferably, sulfonated titanium dioxide; and a hydrophilic separation membrane prepared therefrom. The hydrophilic separation membrane of the present invention has advantages of having excellent water flux and an excellent antifouling property.Type: GrantFiled: December 27, 2016Date of Patent: September 15, 2020Assignee: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Young Ho Ahn, Sivasankaran Ayyaru
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Patent number: 10777866Abstract: Disclosed is a quasi-circulator using an asymmetric directional coupler. The quasi-circulator using the asymmetric directional coupler according to an embodiment of the present invention may enhance a characteristic of isolating a transmitting signal from a receiving signal with the same characteristic as transmitting signal loss of a symmetric directional coupler in the related art by arranging impedance of each line of a directional coupler asymmetrically.Type: GrantFiled: August 22, 2018Date of Patent: September 15, 2020Assignee: RESEARCH COOPERATION FOUNDATION OF THE YEUNGNAM UNIVERSITYInventors: Jong Ryul Yang, Bo Yoon Yoo, Ha Neul Lee, Ju Hee Son
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Patent number: 10768149Abstract: An apparatus for improving transmission directivity according to an embodiment of the present invention includes a phased array probe including a channel 1 transducer and a channel 2 transducer which are arranged at intervals corresponding to a quarter wavelength at a center frequency of a guided wave pulse for long-range ultrasonic testing, and a drive unit which supplies electric pulses with opposite phases to the channel 1 transducer and the channel 2 transducer of the channel 1 transducer and the channel 2 transducer, which is disposed on the front end on the basis of an intended transmission direction, is driven with delay by a time corresponding to a quarter frequency of the center frequency than the other transducer disposed on the rear end.Type: GrantFiled: November 4, 2016Date of Patent: September 8, 2020Assignees: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY, DIGITAL ULTRASONICS CO. LTDInventor: Myoung-Seon Choi
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Patent number: 10722834Abstract: The present application relates to a functional fiber for adsorbing heavy metal and a method for producing the same, and the functional fiber for adsorbing heavy metal of the present application may have a structure in which thiolated metal nanoparticles are attached to a porous fiber, thereby minimizing the pore clogging of the porous fiber to remarkably improve the adsorption capacity of heavy metal materials, may be prepared by applying the dry technology without liquid impregnation, thereby minimizing the pore clogging of the porous fiber and fundamentally blocking the process wastewater generation, and is easy to implement the roll-to-roll system, so that continuous production is possible and thus productivity may be improved.Type: GrantFiled: November 17, 2016Date of Patent: July 28, 2020Assignee: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventor: Jeong Hoon Byeon
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Patent number: 10688425Abstract: The present application relates to a multifunctional filter medium and a method of manufacturing the same. The multifunctional filter medium of the present application is capable of significantly reducing fine dust, harmful microorganisms, and toxic gases and reducing a pressure decrease during filtration due to exclusion of high-density nanofiber, thereby minimizing energy required for filtration and exhibiting sufficient filtration performance as a single filter medium.Type: GrantFiled: December 28, 2016Date of Patent: June 23, 2020Assignee: Research Cooperation Foundation of Yeungnam UniversityInventor: Jeong Hoon Byeon
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Publication number: 20200179686Abstract: Provided is a respiratory muscle strengthening device, in which an inhalation start signal is generated correspondingly at an inhalation start time when a patient inhales air or an exhalation start signal is generated correspondingly at an exhalation start time when the patient exhales air, an electric signal according to the inhalation start signal or the exhalation start signal is transmitted to an electric muscle stimulator via a communication unit, a muscle pad installed on respiratory muscles of the patient enables smooth breathing motion by stimulating the respiratory muscles based on a signal transmitted from the electric muscle stimulator, and a receptor pad is provided to the respiratory muscles such that an alarm of determining whether electric stimulation is normally applied via the state of the respiratory muscles detected through the receptor pad is output, thereby securing reliability of a device.Type: ApplicationFiled: June 20, 2017Publication date: June 11, 2020Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Su Min SON, Eun Yong CHOI, Joon Ha LEE, So Young KWAK