Patents Assigned to Research Development Institute, Inc.
  • Patent number: 6984386
    Abstract: Virion-constrained nanoparticles comprising a shell of virion coat protein(s) surrounding an organic, inorganic and/or organo-metallic non-viral nanoparticle and methods of making and using.
    Type: Grant
    Filed: December 12, 2000
    Date of Patent: January 10, 2006
    Assignee: The Research & Development Institute, Inc.
    Inventors: Trevor Douglas, Mark J. Young
  • Publication number: 20040219655
    Abstract: Virion-constrained nanoparticles comprising a shell of virion coat protein(s) surrounding an organic, inorganic and/or organo-metallic non-viral nanoparticle and methods of making and using.
    Type: Application
    Filed: December 12, 2000
    Publication date: November 4, 2004
    Applicant: The Research & Development Institute, Inc.
    Inventors: Trevor Douglas, Mark J. Young
  • Patent number: 6756404
    Abstract: Autoinducer compounds which enhance gene expression in a wide variety of microorganisms, therapeutic compositions and therapeutic methods wherein gene expression within microorganisms is regulated are disclosed.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: June 29, 2004
    Assignee: The Research & Development Institute, Inc.
    Inventor: Tom Livinghouse
  • Patent number: 6541202
    Abstract: The present invention pertains, in general, to the identification, isolation and use of Telomerase Reverse Transcriptase (TERT) genes and the proteins encoded by such genes. In particular, the present invention pertains to the identification, isolation and use of TERT genes and TERT proteins from several genetically diverse and economically important organisms, including two human pathogens, Candida albicans and Plasmodium falciparum and an agronomic crop species, Oryza sativa.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: April 1, 2003
    Assignee: Research & Development Institute, Inc.
    Inventors: David M. Long, Anneke M. Metz, Ruschelle A. Love
  • Patent number: 6444787
    Abstract: This invention relates to new vaccines against microorganisms based on antigenically mimetic peptides. The invention also relates to methods of discovering such mimetic peptides by first screening peptide-display phage libraries with antibodies against the microbial carbohydrates(s) of interest to locate antigenically mimetic peptides. Vaccines against Group B Streptococcus, or Streptococcus Agalactiae, are preferably produced using this method.
    Type: Grant
    Filed: December 30, 1998
    Date of Patent: September 3, 2002
    Assignee: Research Development Institute, Inc.
    Inventor: Seth H. Pincus
  • Patent number: 6337347
    Abstract: Autoinducer compounds which enhance gene expression in a wide variety of microorganisms, therapeutic compositions and therapeutic methods wherein gene expression within microorganisms is regulated are disclosed.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: January 8, 2002
    Assignee: The Research & Development Institute, Inc.
    Inventor: Tom Livinghouse
  • Patent number: 5821066
    Abstract: A rapid method for the detection, identification and enumeration of specific respiring microorganisms. The method includes steps of a) passing a microbial sample through a collecting device to capture the cells; b) adding to the collecting device a fluorochrome dye specific for the detection of respiring cells and allowing the dye to incubate; c) treating the collecting device with a reactive fluorescent antibody which reacts with a target microorganism of interest present in said microbial sample; d) mounting the collecting device for examination by fluorescence microscopy in which a suitable light system is used to excite the fluorochrome dye and fluorescent antibody to fluoresce; and e) quantifying the respiring cells. Alternative embodiments include the use of immunomagnetic beads and other means of cell capture, and employing fluorescent oligonucleotide probes rather than fluorescent antibodies.
    Type: Grant
    Filed: May 19, 1997
    Date of Patent: October 13, 1998
    Assignee: The Research & Development Institute, Inc.
    Inventors: Barry H. Pyle, Gordon A. McFeters
  • Patent number: 5419887
    Abstract: The isotopes of boron, .sup.10 B and .sup.11 B, are separated by means of a gas-liquid chemical exchange reaction involving the isotopic equilibrium between gaseous BF.sub.3 and a liquid BF.sub.3 . donor molecular addition complex formed between BF.sub.3 gas and a donor chosen from the group consisting of: nitromethane, acetone, methyl isobutyl ketone, or diisobutyl ketone.
    Type: Grant
    Filed: January 25, 1994
    Date of Patent: May 30, 1995
    Assignee: Research & Development Institute, Inc.
    Inventors: Frank P. McCandless, Ronald S. Herbst