Patents Assigned to Research Foundation of CUNY, Hunter College
  • Compositions and methods using myelin-associated glycoprotein (MAG) and inhibitors thereof
    Patent number: 6399577
    Abstract: This invention relates to the novel identification of myelin-associated glycoprotein (“MAG”) as a potent inhibitor of neural regeneration. More particularly, this invention relates to compositions and methods useful for reversing inhibition of neural regeneration in the central and peripheral nervous system. Assays to monitor the effects of MAG on neural regeneration and to identify agents which will block or promote the inhibitory effects of MAG on neural outgrowth are provided. Screening methods for identifying such agents are also provided. This invention also relates to compositions and methods using agents that can reverse the inhibitory effects of MAG on neural regeneration.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: June 4, 2002
    Assignee: Research Foundation of CUNY, Hunter College
    Inventor: Marie T. Filbin
  • Composition and methods using myelin-associated glycoprotein (MAG) and inhibitors thereof
    Patent number: 6203792
    Abstract: This invention relates to the novel identification of myelin-associated glycoprotein (“MAG”) as a potent inhibitor of neural regeneration. More particularly, this invention relates to compositions and methods useful for reversing inhibition of neural regeneration in the central and peripheral nervous system. Assays to monitor the effects of MAG on neural regeneration and to identify agents which will block or promote the inhibitory effects of MAG on neural outgrowth are provided. Screening methods for identifying such agents are also provided. This invention also relates to compositions and methods using agents that can reverse the inhibitory effects of MAG on neural regeneration.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: March 20, 2001
    Assignee: Research Foundation of CUNY, Hunter College
    Inventor: Marie T. Filbin
  • Composition and methods using myelin-associated glycoprotein (MAG) and inhibitors thereof
    Patent number: 5932542
    Abstract: This invention relates to the novel identification of myelin-associated glycoprotein ("MAG") as a potent inhibitor of neural regeneration. More particularly, this invention relates to compositions and methods useful for reversing inhibition of neural regeneration in the central and peripheral nervous system. Assays to monitor the effects of MAG on neural regeneration and to identify agents which will block or promote the inhibitory effects of MAG on neural outgrowth are provided. Screening methods for identifying such agents are also provided. This invention also relates to compositions and methods using agents that can reverse the inhibitory effects of MAG on neural regeneration.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: August 3, 1999
    Assignee: Research Foundation of CUNY, Hunter College
    Inventor: Marie T. Filbin