Abstract: Cloning, expression, viral and delivery vectors and hosts which contain nucleic acid coding for at least one peripheral nervous system specific (PNS) sodium channel peptide (SCP), isolated PNS SCP, and compounds and compositions and methods, are provided, for isolating, crystallizing, x-ray analysing molecular modeling, rational drug designing, selecting, making and using therapeutic or diagnostic agents or ligands having at least one peripheral nervous system specific (PNS) sodium channel (SC) modulating activity.
Type:
Application
Filed:
January 29, 2004
Publication date:
November 18, 2004
Applicants:
The Research Foundation of State University of New York, The SUNY at Stony Brook, ICAgen, Inc. (Allelix cases)
Abstract: Cloning, expression, viral and delivery vectors and hosts which contain nucleic acid coding for at least one peripheral nervous system specific (PNS) sodium channel peptide (SCP), isolated PNS SCP, and compounds and compositions and methods, are provided, for isolating, crystallizing, x-ray analysing molecular modeling, rational drug designing, selecting, making and using therapeutic or diagnostic agents or ligands having at least one peripheral nervous system specific (PNS) sodium channel (SC) modulating activity.
Type:
Grant
Filed:
December 9, 1999
Date of Patent:
March 9, 2004
Assignee:
Research Foundation of State University of New York, The SUNY
at Stony Brook
Inventors:
Gail Mandel, Simon Halegoua, Laurence A. Borden
Abstract: Cloning, expression, viral and delivery vectors and hosts which contain nucleic acid coding for at least one peripheral nervous system specific (PNS) sodium channel peptide (SCP), isolated PNS SCP, and compounds and compositions and methods, are provided, for isolating, crystallizing, x-ray analysing molecular modeling, rational drug designing, selecting, making and using therapeutic or diagnostic agents or ligands having at least one peripheral nervous system specific (PNS) sodium channel (SC) modulating activity.
Type:
Grant
Filed:
May 2, 1997
Date of Patent:
August 29, 2000
Assignee:
Research Foundation of State University of New York, The SUNY at Stony Brook