Abstract: The present disclosure includes a system and method for symbol compression using conditional entropy estimation. One method for symbol compression using conditional entropy estimation includes approximating a quantity of symbol encoding bits for a number of symbols using a conditional entropy estimation. Dictionary entries are generated from the number of symbols so as to minimize a total bit-stream quantity. The total bit-stream quantity includes at least the approximated quantity of symbol encoding bits and a quantity of dictionary entries encoding bits. The symbols are encoded using the dictionary entries as a reference.
Type:
Grant
Filed:
July 31, 2012
Date of Patent:
April 28, 2015
Assignees:
Hewlett-Packard Development Company, L.P., Purdue Research Foundation
Inventors:
Dejan Depalov, Peter Bauer, Charles A. Bouman, Jan Allebach, Yandong Guo
Abstract: Disclosed is a method to construct a device that includes a plurality of nanowires (NWs) each having a core and at least one shell. The method includes providing a plurality of radially encoded NWs where each shell contains one of a plurality of different shell materials; and differentiating individual ones of the NWs from one another by selectively removing or not removing shell material within areas to be electrically coupled to individual ones of a plurality of mesowires (MWs). Also disclosed is a nanowire array that contains radially encoded NWs, and a computer program product useful in forming a nanowire array.
Type:
Application
Filed:
October 22, 2014
Publication date:
April 23, 2015
Applicant:
Brown University Research Foundation
Inventors:
Andre Dehon, Charles M. Lieber, John E. Savage, Eric Rachlin
Abstract: A multicore computer architecture provides for clock dividers on each core, the clock dividers capable of providing rapid changes in the clock frequency of the core. The clock dividers are used to reduce the clock frequency of individual cores spinning while waiting for a synchronization instruction resolution such as a lock variable. Core power demands may be decreased before and after change in dock speed to reduce power bus disruption.
Abstract: The present invention is based, in part, on the discovery that parvovirus (including AAV) capsids can be engineered to incorporate small, selective regions from other parvoviruses that confer desirable properties. The inventors have discovered that in some cases as little as a single amino acid insertion or substitution from a first parvovirus (e.g., an AAV) into the capsid structure of another parvovirus (e.g., an AAV) to create a chimeric parvovirus is sufficient to confer one or more of the desirable properties of the first parvovirus to the resulting chimeric parvovirus and/or to confer a property that is not exhibited by the first parvovirus or is present to a lesser extent.
Type:
Grant
Filed:
January 3, 2011
Date of Patent:
April 21, 2015
Assignees:
The University of North Carolina at Chapel Hill, The University of Florida Research Foundation
Inventors:
Dawn E. Bowles, Chengwen Li, Joseph E. Rabinowitz, Josh Grieger, Mavis Agbandje-McKenna, Richard Jude Samulski
Abstract: A method, apparatus, and system for improved VA-TIRFM microscopy. The method comprises automatically controlled calibration of one or more laser sources by precise control of presentation of each laser relative a sample for small incremental changes of incident angle over a range of critical TIR angles. The calibration then allows precise scanning of the sample for any of those calibrated angles for higher and more accurate resolution, and better reconstruction of the scans for super resolution reconstruction of the sample. Optionally the system can be controlled for incident angles of the excitation laser at sub-critical angles for pseudo TIRFM. Optionally both above-critical angle and sub critical angle measurements can be accomplished with the same system.
Type:
Grant
Filed:
January 14, 2011
Date of Patent:
April 21, 2015
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: The invention provides oil emulsion droplets and a general and facile method for providing same through the use of templating multilayer capsules. The oil emulsion droplets are further useful in fabricating liquid crystal droplet-based biosensors for the detection of target analytes such as bacteria or viruses in a sample.
Type:
Grant
Filed:
January 15, 2009
Date of Patent:
April 21, 2015
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Nicholas L. Abbott, Francesco Caruso, Jugal K. Gupta, Sri Sivakumar
Abstract: The present invention provides systems and methods for transferring heat using a variable composition organic heat transfer fluid that remains liquid over a wide operating temperature range useful for solar heating applications. Variable composition heat transfer fluids of the present invention comprise a miscible mixture, optionally a completely miscible mixture, of a high boiling point component selected for its beneficial high temperature physical properties, and a low freezing point component selected for its beneficial low temperature physical properties. In some embodiments, the low freezing point component is removed from the heat transfer fluid as the heat transfer fluid is heated, for example by being removed in the vapor phase, thereby selectively varying the composition and physical properties (e.g., vapor pressure, boiling point, etc.) of the heat transfer fluid as a function of temperature.
Abstract: The present invention provides membranes having a coating layer comprising cellulose or cellulose derivative and a porous support comprising nanofibers prepared by a process of coating a solution comprising cellulose or a cellulose derivative dissolved in an ionic liquid on to a porous support layer. The present invention is useful for providing improved water flux and high rejection rates for oil/water emulsions. The present invention also provides fluid separation systems in UF, NF, RO and FO, incorporating membranes of the present invention.
Type:
Grant
Filed:
May 23, 2008
Date of Patent:
April 21, 2015
Assignee:
The Research Foundation of State University of New York
Inventors:
Benjamin Chu, Benjamin S. Hsiao, Hongyang Ma
Abstract: A method for predicting a subject's risk factors for ACE-related disorders includes detecting the allelic status of one or more polymorphisms in a nucleic acid sample of the subject.
Type:
Grant
Filed:
April 30, 2008
Date of Patent:
April 21, 2015
Assignee:
The Ohio State University Research Foundation
Inventors:
Wolfgang Sadee, Andrew D. Johnson, Danxin Wang, Audrey C. Papp
Abstract: A system and method of photon trapping spectroscopy to vary the path length of light for use in spectroscopy. The systems and method include a rotating reflector with slits for selectively permitting light to enter and exit into a reflection cavity containing a sample to be analyzed. After entering the cavity, but before exiting, the light is trapped and repeatedly reflects back and forth through a sample, effectively increasing the path length of light through a sample. The effective path length is quickly adjustable by altering the rotation speed of the rotating reflector to alter the time in which the light is trapped within the cavity. The systems and methods provide a spectroscope with a wide dynamic range, low detection limits, and usable with broadband and monochromatic light sources throughout the optical region (ultraviolet to infrared).
Type:
Grant
Filed:
February 21, 2012
Date of Patent:
April 21, 2015
Assignee:
UWM Research Foundation, Inc.
Inventors:
Joseph Aldstadt, III, Peter Geissinger, Beth A. Ruddy, Jörg C. Woehl, John A. Frost
Abstract: A sol to form an inorganic-organic hybrid coating having a thick highly transparent hard coating is described. The hybrid coating is formed from a combined aqueous sol with least one hydrolyzable silane and at least one hydrolyzable metal oxide precursor where the only organic solvents present are those liberated upon hydrolysis of the silanes and metal oxide precursors. In one embodiment an inorganic-organic hybrid coating is formed by combination of a sol, prepared by the hydrolysis of tetraethoxysilane and ?-glycidoxypropyltrimethoxysilane with an excess of water, and a sol, prepared by the hydrolysis of titanium tetrabutoxide and ?-glycidoxypropyltrimethoxysilane with a deficiency of water. A plastic substrate can be coated with the combined sol and the combined sol gelled to a thickness of at least 5 ?m with heating to less than 150° C.
Type:
Grant
Filed:
April 2, 2014
Date of Patent:
April 21, 2015
Assignee:
University of Florida Research Foundation, Inc.
Abstract: Methods and systems for data analysis using covarying data. Eigenvalues and eigenvectors of one or more lagged covariance matrices of data obtained over time may be generated and used to enhance the data.
Type:
Grant
Filed:
February 22, 2013
Date of Patent:
April 21, 2015
Assignee:
University of Georgia Research Foundation, Inc.
Abstract: A method of polymerization for the preparation of conjugated polymers and copolymers comprising dioxypyrrole and/or dioxyfuran repeating units involves the halogen, N-haloimide, or N-haloamine promoted polymerization of monomers and/or oligomers comprising one or more dioxypyrrole and/or dioxyfuran units. The polymerization can be carried out over a wide range of temperatures and can be carried out with or without a solvent. The monomers allow the preparation of polymers having an oligomeric repeating unit comprising a conjugated unit other than a dioxypyrrole or dioxyfuran that is bound to two dioxypyrrole or dioxyfuran units.
Type:
Grant
Filed:
February 13, 2013
Date of Patent:
April 21, 2015
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
John R. Reynolds, Frank Antonio Arroyave-Mondragon
Abstract: Provided are methods and compositions for determining whether an individual has Sjögren's disease (SD). The method entails determining in a biological sample from the individual the presence of antibodies directed to salivary gland protein 1 (SP-1), parotid secretory protein (PSP), carbonic anhydrase 6 (CA6), or determining a combination of the antibodies. Determining that the individual has SD is based on the presence of the antibodies. The method provides for detection of early SD. Kits for antibody detection containing the antigens to which the antibodies of SD patients are directed are also provided.
Type:
Grant
Filed:
May 22, 2014
Date of Patent:
April 21, 2015
Assignee:
The Research Foundation For The State University of New York
Abstract: The present invention relates to nucleic acids encoding mosaic clade M HIV-1 Env polypeptides and to compositions and vectors comprising same. The nucleic acids of the invention are suitable for use in inducing an immune response to HIV-1 in a human.
Type:
Grant
Filed:
April 26, 2011
Date of Patent:
April 21, 2015
Assignees:
Los Alamos National Security, LLC, Duke University, Beth Israel Deaconess Medical Center, The University of Alabama at Birmingham Research Foundation
Inventors:
Bette T. Korber, William Fischer, Hua-Xin Liao, Barton F. Haynes, Norman Letvin, Beatrice H. Hahn
Abstract: Effective systems and methods for improving neural communication impairment of a vertebrate being and affecting motor activity of a peripheral body part including a first signal-providing component configured to provide pulsed peripheral stimulation signals at the peripheral body part, a second signal-providing component configured to provide a pulsed motor cortex stimulation signal to a motor cortex area, a substantially DC signal-providing component configured to provide direct current spinal stimulation signal at a neural spinal junction and a controller component configured to control timing of the pulsed peripheral stimulation signals and the pulsed motor cortex stimulation signal.
Type:
Grant
Filed:
March 7, 2014
Date of Patent:
April 21, 2015
Assignee:
The Research Foundation of the City University of New York
Abstract: Disclosed are heterogeneous crystals for use in a laser cavity and methods of forming the crystals. A crystal can be a monolithic crystal containing regions that are based upon the same host material but differ from one another according to some material feature such that they can perform various functions related to lasing. Disclosed methods include hydrothermal growth techniques for the growth of differing epitaxial layers on a host. A host material can be doped in one region with a suitable active lasing ion and can be formed with another region that is undoped and can act as an endcap, a waveguide cladding layer, or a substrate to provide strength and/or contact to a heat sink. Regions can be formed with controlled thickness in conjunction. Following formation, a heterogeneous crystal can be cut, polished and coated with mirror films at each end for use in a laser cavity.
Type:
Grant
Filed:
July 8, 2010
Date of Patent:
April 21, 2015
Assignee:
Clemson University Research Foundation
Inventors:
Joseph W. Kolis, Colin D. McMillen, J. Matthew Mann, John M. Ballato
Abstract: A computer aided diagnostic system and automated method diagnose lung cancer through modeling and analyzing the visual appearance of pulmonary nodules. A learned appearance model used in such analysis describes the appearance of pulmonary nodules in terms of voxel-wise conditional Gibbs energies for a generic rotation and translation invariant second-order Markov-Gibbs random field (MGRF) model of malignant nodules with analytically estimated characteristic voxel neighborhoods and potentials.
Type:
Grant
Filed:
February 8, 2012
Date of Patent:
April 21, 2015
Assignee:
University of Louisville Research Foundation, Inc.
Abstract: Phosphor compositions, white phosphor compositions, methods of making white phosphor compositions, tinted white phosphor compositions, methods of making tinted white phosphor compositions, LEDs, methods of making LEDs, light bulb structures, paints including phosphor compositions, polymer compositions including phosphor compositions, ceramics including phosphor compositions, and the like are provided.
Type:
Grant
Filed:
August 2, 2011
Date of Patent:
April 21, 2015
Assignee:
University of Georgia Research Foundation, Inc.
Inventors:
William M. Yen, Zhiyi He, Sergei Basun, Xiao-jun Wang, Gennaro J. Gama