Abstract: An information processing system includes an objective data acquisition unit and a numerical analysis processing unit (or structure inference unit). The objective data acquisition unit acquires data of the object of numerical analysis (or a design simulation of a construction) expressed as a mesh shape. The numerical analysis processing unit (or structure inference unit) uses a machine learning model obtained by performing machine learning on the result of numerical analysis of physical properties (or a design simulation of a construction) in units of relationships between two adjacent nodes in graph data corresponding to a mesh shape to acquire an inference result inferring a result of numerical analysis (or a result of a design simulation of a construction) for the object of numerical analysis (or a design simulation of a construction).