Patents Assigned to Research Institute for Glycotechnology
  • Apoptosis inducers
    Patent number: 6593311
    Abstract: Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: July 15, 2003
    Assignees: Takara Shuzo Co., Ltd., Research Institute for Glycotechnology
    Inventors: Takeshi Sakai, Hideo Kitano, Fu-Gong Yu, Shinji Nakayama, Kaoru Kojima, Hitomi Kimura, Yoshikuni Nakanishi, Kaoru Katayama, Takanari Tominaga, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
  • Biologically pure culture of Fucoidanobacter marinus SI-0098 (FERM BP-5403)
    Patent number: 6379947
    Abstract: A novel endo-fucoidan-lyase and a novel microorganism, Fucoidanobacter marinus SI-0098 (FERM BP-5403) useful in the production of sugar compounds are disclosed Sugar compounds represented by the following general formula (1), wherein at least one of alcoholic hydroxyl group has been sulfated, or salts thereof: wherein Y represents hydrogen or a group represented by the following formula (2).
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: April 30, 2002
    Assignees: Takara Shuzo Co., Ltd., Research Institute for Glycotechnology
    Inventors: Takeshi Sakai, Hitomi Kimura, Kaoru Kojima, Katsushige Ikai, Sumiko Akiyoshi, Yoshikuni Nakanishi, Ikunoshin Kato
  • Endo-fucoidan-lyase
    Patent number: 6277616
    Abstract: An isolated endo-fucoidan-lyase is described. The enzyme acts on fucoidan, has a pH optimum from 6 to 10, and has an optimum pH from 30 to 40° C. The enzyme can be isolated from Flavobacterium sp. FERM BP-5402. The enzyme is used to obtain sugar compounds which are useful in the study on carbohydrates.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: August 21, 2001
    Assignees: Takara Shuzo Co. Ltd., Research Institute for Glycotechnology
    Inventors: Takeshi Sakai, Hitomi Kimura, Kaoru Kojima, Katsushige Ikai, Sumiko Akiyoshi, Yoshikuni Nakanishi, Ikunoshin Kato
  • Apoptosis inducers
    Patent number: 6207652
    Abstract: Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.
    Type: Grant
    Filed: April 9, 1998
    Date of Patent: March 27, 2001
    Assignees: Takara Shuzo Co., Ltd., Research Institute for Glycotechnology
    Inventors: Takeshi Sakai, Hideo Kitano, Fu-Gong Yu, Shinji Nakayama, Kaoru Kojima, Hitomi Kimura, Yoshikuni Nakanishi, Kaoru Katayama, Takanari Tominaga, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
  • Oligosaccharides from enzymatic cleavage of fucoidan
    Patent number: 6054577
    Abstract: A novel endo-fucoidan-lyase and a novel microorganism useful in the production of sugar compounds. Sugar compounds represented by the following general formula (1), wherein at least one of alcoholic hydroxyl group has been sulfated, or salts thereof: ##STR1## wherein Y represents hydrogen or a group represented by the following formula (2).
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: April 25, 2000
    Assignees: Takara Shuzo Co., Ltd., Research Institute For Glycotechnology
    Inventors: Takeshi Sakai, Hitomi Kimura, Kaoru Kojima, Katsushige Ikai, Sumiko Akiyoshi, Yoshikuni Nakanishi, Ikunoshin Kato