Abstract: The present invention relates to pharmaceutical compositions for treating blood cancer, which includes 4?-thio-5-aza-2?-deoxycytidine (Aza-T-dCyd), and methods of treating blood cancer using a composition for oral administration that includes Aza-T-dCyd. The present invention provides a significant blood cancer therapeutic effect without having toxicity in a blood cancer mouse model or a human even with the Aza-T-dCyd dose conventionally known to have toxicity. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Provided is an apparatus and method for encoding/decoding a moving picture based on adaptive scanning. The moving picture apparatus and method can increase a compression rate based on adaptive scanning by performing intra prediction onto blocks of a predetermined size, and scanning coefficients acquired from Discrete Cosine Transform (DCT) of a residue signal and quantization differently according to the intra prediction mode. The moving picture encoding apparatus includes: a mode selector for selecting and outputting a prediction mode; a predictor for predicting pixel values of pixels to be encoded of an input video based on the prediction mode to thereby output a residue signal block; a transform/quantization unit for performing DCT onto the residue signal block and quantizing the transformed residue signal block; and an encoder for adaptively scanning and encoding the quantized residue signal block based on the prediction mode.

Abstract: Systems and methods are provided for optimizing a driver's trajectory around a race track. The system can receive driver data representing driver inputs to a vehicle. A vehicle state can be determined for at least one location on the race track based on the received driver data. Expert driver data can be determined representing inputs of an expert driver at the determined vehicle state for the at least one location. The system can predict how the expert driver would proceed from each current vehicle state based on the expert driver data and map the current vehicle state at the at least one location to a recommended trajectory from each current vehicle state based on predicting how the expert driver would proceed.

Abstract: Embodiments of the present invention provide for syntheses and uses of tri-substituted mono-hydrogen ferrocyanides for efficient hydroxyl radical generators. For example, the present invention provides for the syntheses of mono-hydrogen ferrocyanides of the general formula M3HFe(CN)6 in which iron has an oxidation number of +2 (ferro) and the positive counter-ion, M, belongs mainly to the group of the alkali metals such as Na+, K+and Li+, or to organic alkyl cations such as imidazole derivatives.

Abstract: A power semiconductor device includes a semiconductor substrate, a drift layer, a well region, a doped region, two dummy trenches, a gate structure and a dielectric layer. The semiconductor substrate is doped to have a first conductive channel. The drift layer on the semiconductor substrate is doped to have the first conductive channel. The well region on the drift layer is doped to have a second conductive channel having a polarity opposite to that of the first conductive channel. The doped region on the well region is doped to have the first conductive channel. Two dummy trenches pass through the doped region and the well region. Each of the dummy trenches has a dummy gate. The gate structure has a real gate and is between the dummy trenches. The dielectric layer isolates the dummy gate and the real gate from the doped region, the well region and the drift layer.

Abstract: An electric vehicle (EV) battery pack replacement system includes a replacement pack ramp structure having a replacement pack ramp, a vehicle-mountable battery pack receptacle, and a vehicle-mountable replacement pack coupling system structured to be operable to connect a vehicle to a replacement pack positioned on the ramp during movement of the vehicle over the ramp. Further movement of the vehicle over the ramp after connection to the replacement pack to the vehicle moves the replacement pack up the ramp. The ramp is structured so that movement of the replacement pack up the ramp causes the replacement pack to be positioned in in the receptacle. The system uses continuous motion of the vehicle and the replacement pack coupling system for loading a new battery, obviating the need for robotics or other active or powered infrastructure external to the vehicle.

Abstract: A method according to an embodiment of the present invention corresponds to a method for transmitting, by a gateway, a synchronization signal block (SSB) through a plurality of satellites, and may comprise the steps of: determining satellite identification SSBs for identifying a plurality of satellites, respectively; determining beam identification SSBs for identifying beams usable for the plurality of satellites, respectively; and controlling the satellite identification SSBs and the beam identification SSBs to be transmitted to the plurality of satellites, respectively, through a predetermined resource, wherein the satellite identification SSBs and each of the beam identification SSBs have different SSB indices from each other.

Abstract: A method of manufacturing triacetonamine includes (a) introducing an acetone and an ammonia into a first reactor in the presence of a first acidic catalyst to form an acetonin; (b) introducing the acetonin and water into a second reactor in the presence of a second acidic catalyst to form a triacetonamine and side products, wherein the side products include diacetone alcohol, diacetone amine, mesityl oxide, 2,2,4,6-tetramethyl-2,3-dihydropyridine, or a combination thereof; (c) separating the triacetonamine and the side products by distillation under reduced pressure; (d) introducing the side products and water into a third reactor to heat and crack the side products in the presence of an amphiphilic catalyst to form acetone; and (e) introducing the acetone obtained from step (d) into the first reactor.

Abstract: Provided are calibrating method and system of setting value of grid-related relay protection of new energy station, wherein generating module of calibrating template generates setting value calibrating template of target new energy station based on names of each of protective setting value items and units of each of protective setting value items of target new energy station; generating module of setting value table to be calibrated generates setting value table to be calibrated of target new energy station based on actual values of each of protective setting value items and setting value calibrating template; determining module of standard setting value table determines standard setting value table of target new energy station from protective setting value calibration database according to new energy station number of target new energy station; and calibrating module of protective setting value calibrates setting value table to be calibrated according to standard setting value table.

Abstract: The invention discloses a method and system for detecting a retaining wall suitable for an automatic driving vehicle. The method comprises: obtaining original data acquired during a backing process of a vehicle and used for detecting a retaining wall, and processing the original data to obtain finally processed data of the retaining wall; obtaining ground data during the backing process of the vehicle, and sequentially performing ground determination and ground elimination on the ground data to obtain non-ground point cloud data; and obtaining distance information between a rear end of the vehicle and the retaining wall and integrity data of the retaining wall by calculation according to the finally processed data of the retaining wall and the non-ground point cloud data.

Abstract: A semiconductor device includes a substrate, a dummy gate structure, and a gate structure. The substrate has a dummy gate trench and a gate trench, and includes a first well region, a second well region and a source region. The first well region is formed by doping at least one element from a first element group, and has a first conductive channel. The second well region is formed by doping at least one element from a second element group, the second well region is on the first well region and has a second conductive channel, a polarity of the second conductive channel is opposite to that of the first conductive channel. The dummy gate structure is in the dummy gate trench of the substrate, and a portion of the dummy gate structure is in the first well region. The gate structure is between the adjacent dummy gate structures.

Abstract: Sarbecoviruses (lineage B of genus Betacoronavirus) have caused two major outbreaks during the past two decades: SARS-CoV in 2003, and SARS-CoV-2 from 2019. SARS-CoV-2 vaccines will be essential to reduce morbidity and mortality. Therefore, universal vaccines against this class of viruses are key to ending the current pandemic, but also for preventing additional emergent variations and future outbreaks of SARS-like viruses that are continuously found from nature reservoirs. Now, the inventors produced an antibody that is directed against a surface antigen (i.e., CD40) of an antigen presenting cell (i.e., dendritic cell) wherein the heavy chain is conjugated or fused to a protein N polypeptide of SAR-CoV-2 and the light chain is fused to a RBD polypeptide. In particular, the inventors show that said antibody could elicit immune responses against Sarbecoviruses.

Abstract: A method for a physical design tool to recommend design alternatives based on responses to semantic prompts is described. The method includes identifying first design action patterns elicited by a specific semantic prompt that differ across individual designers based on historical data. The method also includes generating sequences of actions with varying similarity to the individual designers to present alternatives to new designers. The method further includes identifying second design action patterns that differ across sematic prompts with different linguistic properties. The method also includes training a behavioral model of each of the individual designers based on responses to the specific semantic prompt, responses to the sematic prompts with the different linguistic properties, and the sequences of actions with the varying similarity. The method further includes displaying the design alternatives recommended to an individual designer based on the behavioral model created for the individual designer.

Abstract: The present invention provides a method of detecting one or more Klebsiella species within a sample from a subject, the method comprising: subjecting DNA and/or RNA from the sample to a PCR amplification reaction using primer pairs targeting species-specific canonical single nucleotide polymorphisms (canSNPs); and analyzing amplification products resulting from the PCR amplification reaction to detect the one or more Klebsiella species. The present invention also provides a kit for detection of one or more Klebsiella species, Klebsiella clonal groups, AMR genes, and/or virulence genes, the kit comprising primer pairs targeting species-specific canSNPs, K. pneumoniae genes M1 and M2, clonal group-specific canSNPs, AMR genes, and/or virulence genes.

Abstract: Disclosed herein are a duty cycle monitoring method and apparatus for a memory interface, including receiving a clock signal as input and generating a first delay time offset and a second delay time offset, receiving the clock signal and the first delay time offset and then outputting a first delayed signal, receiving the first delayed signal and the second delay time offset and then outputting a second delayed signal, receiving the clock signal and the second delayed signal and then outputting a delay value corresponding to a half-period of the clock signal, and monitoring, based on the first delayed signal, whether a duty cycle of the clock signal conforms to a duty cycle specification.

Abstract: An acoustic resonance diagnostic method for detecting structural degradation is provided. The method includes steps as follows: Firstly, a training model is built using a deep neural network. At least two training acoustic signals are inputted to the training model to carry a training. A diagnostic model is built according to a result of the training using a CNN. A plurality of under-test sound wave signals are captured from an under-test section of an under-test structure. An AI is used to filter data invalid for detecting structural degradation from the under-test sound wave signals. A structural degradation state of the under-test section is determined according to a remaining portion of the under-test sound wave signals through the diagnostic model.

Abstract: The present invention relates to a transmembrane domain derived from human LRRC24 protein. More specifically, the present invention relates to a transmembrane domain derived from the human LRRC24 protein (LRRC24P transmembrane domain) or a cell-penetrating peptide, and an intracellular delivery system comprising same. The transmembrane domain derived from the human LRRC24 protein of the present invention can be used to deliver cargo materials such as compounds, biomolecules, and various polymer materials into cells. Since the LRRC24P transmembrane domain of the present invention exhibits higher cell penetration efficiency compared to conventional cell-penetrating peptides and is derived from human proteins, thus avoiding side effects and immune responses caused by peptides derived from foreign proteins, it can be usefully used as an effective intracellular delivery method for compounds, biomolecules, and various polymer materials applied to the human body.

Abstract: Provided are a fluorescence generating device and a digital PCR analysis system including the same. The fluorescence generating device includes a clad layer on a substrate, an optical waveguide arranged in a first direction within the clad layer, and a housing which is disposed on the optical waveguide and the clad layer and has a micro fluid channel extending in a second direction. The optical waveguide includes an input waveguide which is provided within one side of the clad layer and provides excitation light to a liquid drop within the micro fluid channel to generate fluorescent light, and an output waveguide which is provided within the other side of the clad layer and has an output inclined surface that reflects the fluorescent light.

Abstract: An audio signal encoding and decoding method using a neural network model, and an encoder and decoder for performing the same are disclosed. A method of encoding an audio signal using a neural network model, the method may include identifying an input signal, generating a quantized latent vector by inputting the input signal into a neural network model encoding the input signal, and generating a bitstream corresponding to the quantized latent vector, wherein the neural network model may include i) a feature extraction layer generating a latent vector by extracting a feature of the input signal, ii) a plurality of downsampling blocks downsampling the latent vector, and iii) a plurality of quantization blocks performing quantization of a downsampled latent vector.

Abstract: Provided is a method of fabricating a semiconductor package. The method of fabricating the semiconductor package include preparing a lower element including a lower substrate, a lower electrode, an UBM layer, and a reducing agent layer, providing an upper element including an upper substrate, an upper electrode, and a solder bump layer, providing a pressing member on the upper substrate to press the upper substrate to the lower substrate, and providing a laser beam passing through the pressing member to bond the upper element to the lower element.