Patents Assigned to Research Triangle Insitute
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Patent number: 8847487Abstract: A device for stimulable light emission that includes a fiber mat of nanofibers having an average fiber diameter in a range between 100 and 2000 nm, and includes plural stimulable particles disposed in association with the nanofibers. The stimulable particles produce secondary light emission upon receiving primary light at a wavelength ?. The average fiber diameter is comparable in size to the wavelength ? in order to provide scattering sites within the fiber mat for the primary light. Various methods for making suitable luminescent nanofiber mats include: electrospinning a polymer solution including or not including the stimulable particles and forming from the electrospun solution nanofibers having an average fiber diameter between 100 and 2000 nm. Methods, which electrospin without the stimulable particles, introduce the stimulable particles during electrospinning or after electrospinning to the fibers and therefore to the resultant fiber mat.Type: GrantFiled: July 10, 2013Date of Patent: September 30, 2014Assignee: Research Triangle InsituteInventors: James Lynn Davis, Anthony L. Andrady, David S. Ensor, Li Han, Howard J. Walls
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Publication number: 20120077014Abstract: Apparatus and method for producing fibrous materials in which the apparatus includes an extrusion element configured to electrospin a substance from which the fibers are to be composed by an electric field extraction of the substance from a tip of the extrusion element, a collector disposed from the extrusion element and configured to collect the fibers, a chamber enclosing the collector and the extrusion element, and a control mechanism configured to control a gaseous environment in which the fibers are to be electrospun. The apparatus and method provide a way to produce a fiber collection having a plurality of nanofibers disposed in relation to each other. The nanofibers in the fiber collection are preferentially oriented along a longitudinal axis of the fiber collection.Type: ApplicationFiled: September 23, 2011Publication date: March 29, 2012Applicant: Research Triangle InsituteInventors: Anthony L. ANDRADY, David S. ENSOR, Randall J. NEWSOME
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Publication number: 20100031617Abstract: A filtration device including a filtration medium having a plurality of nanofibers of diameters less than 1 micron formed into a fiber mat in the presence of an abruptly varying electric field. The filtration device includes a support attached to the filtration medium and having openings for fluid flow therethrough. A device for making a filter material. The device includes an electrospinning element configured to electrospin a plurality of fibers from a tip of the electrospinning element, a collector opposed to the electrospinning element configured to collect electrospun fibers on a surface of the collector, and an electric field modulation device configured to abruptly vary an electric field at the collector at least once during electrospinning of the fibers. A method for making a filter material.Type: ApplicationFiled: October 8, 2009Publication date: February 11, 2010Applicant: Research Triangle InsituteInventors: DAVID S. ENSOR, Howard J. Walls, Anthony L. Andrady, Teri A. Walker
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Publication number: 20090318490Abstract: Compounds and methods for promoting smoking cessation. The compounds may be used to treat a variety of other conditions and disease states.Type: ApplicationFiled: August 31, 2009Publication date: December 24, 2009Applicant: Research Triangle InsituteInventor: F. Ivy CARROLL
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Publication number: 20080063741Abstract: Apparatus and method for producing fibrous materials in which the apparatus includes an extrusion element configured to electrospin a substance from which the fibers are to be composed by an electric field extraction of the substance from a tip of the extrusion element, a collector disposed from the extrusion element and configured to collect the fibers, a chamber enclosing the collector and the extrusion element, and a control mechanism configured to control a gaseous environment in which the fibers are to be electrospun. The method includes providing a substance from which the fibers are to be composed to a tip of an extrusion element, applying an electric field to the extrusion element in a direction of the tip, controlling a gaseous environment about where the fibers are to be electrospun, and electrospinning the substance from the tip of the extrusion element by an electric field extraction of the substance from the tip into the controlled gaseous environment.Type: ApplicationFiled: November 6, 2007Publication date: March 13, 2008Applicant: Research Triangle InsituteInventors: Anthony Andrady, David Ensor
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Publication number: 20060228435Abstract: Apparatus and method for electrospinning fibers in which the apparatus includes a spray head having a longitudinal axis and including at least one electrospinning element disposed in a peripheral wall of the spray head surrounding the longitudinal axis. The electrospinning element includes a passage by which a substance from which the fibers are to be electrospun is provided to a tip of the electrospinning element. The electrospinning element extends from the peripheral wall in a direction from the longitudinal axis and is configured to electrospin the fibers by electric field extraction of the substance from the tip of the electrospinning element.Type: ApplicationFiled: April 8, 2004Publication date: October 12, 2006Applicant: Research Triangle InsituteInventors: Anthony Andrady, David Ensor, Randall Newsome
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Publication number: 20060086118Abstract: A structure, system and method for controlling a temperature of a heat generating device in a solid medium, wherein heat is extracted from the medium into at least one heat extraction device, the heat extraction device dissipates heat into an environment apart from the medium by a heat sink thermally coupled to the heat extraction device; and heat from the medium is dissipated into the heat sink by a first thermal interface material thermally coupling the heat sink to the medium.Type: ApplicationFiled: October 22, 2004Publication date: April 27, 2006Applicant: Research Triangle InsituteInventors: Rama Venkatasubramanian, Randall Alley, Pratima Addepalli, Anil Reddy, Edward Siivola, Brooks O'Quinn, Kip Coonley, John Posthill, Thomas Colpitts
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Publication number: 20060069111Abstract: Compounds and methods for promoting smoking cessation. The compounds may be used to treat a variety of other conditions and disease states.Type: ApplicationFiled: November 14, 2005Publication date: March 30, 2006Applicant: Research Triangle InsituteInventor: F. Carroll
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Publication number: 20050224998Abstract: Apparatus and method for producing fibrous materials in which the apparatus includes an enclosure having an inlet configured to receive a substance from which the fibrous materials are to be composed, a common electrode disposed in the enclosure, and plural extrusion elements provided in a wall of the enclosure opposite the common electrode so as to define between the plural extrusion elements and the common electrode a space in communication with the inlet to receive the substance in the space. In the method, a substance from which the fibrous materials are to be composed is fed to the enclosure having the plural extrusion elements, a common electric field is applied to the extrusion elements in a direction in which the substance is to be extruded, the substance is extruded through the extrusion elements to tips of the extrusion elements, and the substance is electrosprayed from the tips to form the fibrous materials.Type: ApplicationFiled: April 8, 2004Publication date: October 13, 2005Applicant: Research Triangle InsituteInventors: Anthony Andrady, David Ensor
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Publication number: 20050209263Abstract: Methods of forming camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex.Type: ApplicationFiled: May 17, 2005Publication date: September 22, 2005Applicant: Research Triangle InsituteInventors: Mansukh Wani, Govindarajan Manikumar, Monroe Wall, Michael Wall
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Publication number: 20040266803Abstract: Methods of forming camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex.Type: ApplicationFiled: June 27, 2003Publication date: December 30, 2004Applicant: Research Triangle InsituteInventors: Mansukh C. Wani, Govindarajan Manikumar, Monroe E. Wall, Michael A. Wall
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Publication number: 20030176434Abstract: Compounds and methods for promoting smoking cessation. The compounds may be used to treat a variety of other conditions and disease states.Type: ApplicationFiled: January 7, 2003Publication date: September 18, 2003Applicant: Research Triangle InsituteInventor: F. Ivy Carroll
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Publication number: 20030106641Abstract: A plasma processing system and method wherein a power source produces a magnetic field and an electric field, and a window disposed between the power source and an interior of a plasma chamber couples the magnetic field into the plasma chamber thereby to couple power inductively into the chamber and based thereon produce a plasma in the plasma chamber. The window can be shaped and dimensioned to control an amount of power capacitively coupled to the plasma chamber by means of the electric field so that the amount of capacitively coupled power is selected in a range from zero to a predetermined amount. Also, a tuned antenna strap having r.f. power applied thereto to produce a standing wave therein can be arranged adjacent the window to couple magnetic field from a current maximum formed in the strap to the interior of the chamber.Type: ApplicationFiled: January 23, 2003Publication date: June 12, 2003Applicant: Research Triangle InsituteInventors: Robert J. Markunas, Gaius G. Fountain, Robert C. Hendry
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Publication number: 20030099279Abstract: A thermoelectric structure and device including at least first and second material systems having different lattice constants and interposed in contact with each other, and a physical interface at which the at least first and second material systems are joined with a lattice mismatch and at which structural integrity of the first and second material systems is substantially maintained. The at least first and second material systems have a charge carrier transport direction normal to the physical interface and preferably periodically arranged in a superlattice structure.Type: ApplicationFiled: October 7, 2002Publication date: May 29, 2003Applicant: Research Triangle InsituteInventors: Rama Venkatasubramanian, Edward Siivola, Thomas Colpitts, Brooks O'Quinn