Patents Assigned to Research
  • Publication number: 20200171655
    Abstract: An automatic control method and an automatic control device are provided. The automatic control device includes a processing unit, a memory unit and a camera unit. The memory unit records an object database and a behavior database. When the automatic control device is operated in an automatic learning mode, the camera unit obtains a continuous image, and the processing unit analyzes the continuous image to determine whether there is an object being moved and matching an object model recorded in the object database in a first placement area. When the continuous image displays the object is moved, the processing unit obtain control data corresponding to moving the object from the first placement area to a second placement area, and the processing unit records the control data to the behavior database. The control data includes trajectory data and motion posture data of the object.
    Type: Application
    Filed: November 21, 2019
    Publication date: June 4, 2020
    Applicant: Metal Industries Research & Development Centre
    Inventors: Shi-Wei Lin, Fu-I Chou, Chun-Ming Yang, Wei-Chan Weng, Chih-Chin Wen
  • Publication number: 20200172554
    Abstract: Provided are 2-(piperidin-1-yl)pyrimidin-4(3H)-ones or pharmaceutically acceptable salts thereof, each characterized by having a 1,8-diazaspiro[4.5]deca-3-ene, 1-oxa-8-azaspiro[4.5]deca-3-ene, 2,8-diazaspiro[4.5]deca-3-ene, 2-oxa-8-azaspiro[4.5]deca-3-ene, 2,9-diazaspiro[5.5]undeca-3-ene, 1-oxa-9-azaspiro[5.5]undeca-3-ene, 1,9-diazaspiro[5.5]undeca-4-ene, or 3,9-diazaspiro[5.
    Type: Application
    Filed: June 30, 2017
    Publication date: June 4, 2020
    Applicants: RIKEN, JAPANESE FOUNDATION FOR CANCER RESEARCH
    Inventors: Minoru YOSHIDA, Hiroyuki SEIMIYA, Masayuki OKUE, Yoko YASHIRODA, Fumiyuki SHIRAI, Takeshi TSUMURA, Yuko KANO, Kenichi WASHIZUKA, Nobuko YOSHIMOTO, Yasuko KOUDA, Takehiro FUKAMI, Tsubasa CHIKADA, Takashi WATANABE
  • Publication number: 20200171170
    Abstract: This document relates to materials and methods for activating naïve T cells in vivo. For example, methods of activating naïve T cells in vivo to treat cancer are provided.
    Type: Application
    Filed: June 15, 2018
    Publication date: June 4, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Larry R. Pease
  • Publication number: 20200172938
    Abstract: The present disclosure provides a method for domesticating Saccharomyces cerevisiae which is resistant to fermentation inhibitors, high temperature and high concentration of ethanol. The method comprises a primary domestication and a secondary domestication of the S. cerevisiae, wherein the primary domestication comprises the steps of replacing the fermented mash with fresh liquefied mash and continuing fermentation when the ethanol content in the fermented mash reaches a higher concentration (>12% (v/v)), the replacement is performed for at least 20 times, and the time interval of replacements is 20-30 hours; the secondary domestication comprises the steps of performing high-temperature domestication on the primary domesticated strain by a temperature gradient and replacing the fermented mash for multiple times, wherein the temperature is raised by 0.5° C.-2° C. every 18-24 times of replacement. The domesticated S.
    Type: Application
    Filed: December 2, 2019
    Publication date: June 4, 2020
    Applicants: COFCO (Jilin) Bio-Chemical Technology Co., Ltd., COFCO Bio-Energy (Zhaodong) Co., Ltd., Nutrition & Health Research Institute, COFCO Corporation
    Inventors: Yi TONG, Yi LI, Junqi ZHANG, Taibo HE, Zexing WANG, Bo HOU, Hui LIU, Fan LI, Lida WU
  • Publication number: 20200172604
    Abstract: Agents which inhibit Gads dimerization are provided. Accordingly there is provided an agent which inhibits Gads (SEQ ID NO: 1) dimerization, the agent interacting with a pharmacophore binding site comprising an amino acid selected from the group consisting of F55, P56, W58, F59, E61, G62, A84-F92, V107-N111, Y115, F116, L125 and N126 of SEQ ID NO: 1. Also provided an agent which inhibits Gads (SEQ ID NO: 1) dimerization, the agent interacting with a pharmacophore binding site comprising an amino acid sequence of an SH3 domain of SEQ ID NO: 1. Also provided are methods of inhibiting activation of a T cell and/or a mast cell and methods of treating or preventing a disease associated with activation of T cells or an allergic response.
    Type: Application
    Filed: May 22, 2018
    Publication date: June 4, 2020
    Applicant: Technion Research & Development Foundation Limited
    Inventor: Deborah YABLONSKI
  • Publication number: 20200172014
    Abstract: Embodiments of the disclosure provide a camera system for a vehicle and a sensing method using such a camera system. The camera system includes a plurality of cameras each configured with a different camera setting. The cameras collectively keep a predetermined image space in focus. The predetermined image space includes at least one object. The camera system further includes a controller. The controller is configured to receive image data captured by the plurality of cameras of the predetermined image space, and determine depth information of the at least one object based on the image data.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 4, 2020
    Applicant: DiDi Research America, LLC
    Inventors: Zafar Takhirov, Sen Hu
  • Publication number: 20200173039
    Abstract: A method for hydrogen evolution by electrolysis includes soaking a membrane electrode assembly into an alkaline aqueous solution. The membrane electrode assembly includes an anode having a first catalyst layer on a first gas-liquid diffusion layer, a cathode having a second catalyst layer on a second gas-liquid diffusion layer, and a cationic exchange membrane between the first catalyst layer of the anode and the second catalyst layer of the cathode. The first catalyst layer, the second catalyst layer, or both of the above has a chemical structure of MxRuyN2, wherein M is Ni, Co, Fe, Mn, Cr, V, Ti, Cu, or Zn, 0<x<1.3, 0.7<y<2, and x+y=2, wherein MxRuyN2 is cubic crystal system or amorphous. The method also applies a voltage to the anode and the cathode for electrolysis of the alkaline aqueous solution, thereby producing hydrogen at the cathode and producing oxygen at the anode.
    Type: Application
    Filed: November 30, 2018
    Publication date: June 4, 2020
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Hsin Lin, Li-Duan Tsai, Yu-Ming Lin, Wen-Hsuan Chao, Chiu-Ping Huang, Pin-Hsin Yang, Hsiao-Chun Huang, Jiunn-Nan Lin
  • Publication number: 20200170951
    Abstract: The present invention relates to nano-resin particles that are suitable for pharmaceutical use and their use in the pharmaceutical field. The present invention provides nano-sized resin particles having a particle size distribution characterized in that D90 value is between 200 nanometers to 900 nanometer and D10 value is not less than 50 nanometers, wherein the nano-resin particles are in pure form and safe for pharmaceutical use. The present invention further relates to pharmaceutical compositions comprising these purified nano-resin particles and their use in the treatment of diseases.
    Type: Application
    Filed: December 9, 2019
    Publication date: June 4, 2020
    Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED
    Inventors: Ajay Jaysingh Khopade, Arindam Halder, Shivam Umeshkumar Upadhyay
  • Publication number: 20200175686
    Abstract: Video processing methods and the associated system architecture for measuring transformation in objects, including pupils, entail the following steps: 1. Motion correction; 2. Object (eye) detection; 3. Image correction; and 4. Fourier-based analysis for item (in some embodiments the item is a pupil) motion estimation.
    Type: Application
    Filed: November 26, 2019
    Publication date: June 4, 2020
    Applicant: Purdue Research Foundation
    Inventors: Pavlos P. Vlachos, Meyers Brett
  • Publication number: 20200177105
    Abstract: The disclosure provides an electricity generating insert for a piece of footwear, the insert can be removably placed in the heel portion, e.g. under the insole. The insert comprises a multilayer piezoelectric stack that alternatively flexes under the compression-decompression that occurs during locomotion, which flexing causes friction in the stack to generate electricity capable of charging electronic devices and the like, e.g. via a port on the footwear.
    Type: Application
    Filed: November 8, 2019
    Publication date: June 4, 2020
    Applicant: The Research Foundation for The State University of New York
    Inventors: Ya Wang, Haili Liu
  • Patent number: 10671093
    Abstract: One embodiment provides an azimuthal pointing system for scientific ballooning. An apparatus, method and/or system are configured to drive a motor to twist a torsion member of a torsion pendulum and to utilize a restoring force of the torsion member to adjust a pointing direction (i.e., pointing angle) of a payload. The torsion pendulum includes the torsion member, the payload and the motor. The payload is coupled to the torsion member by the motor.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: June 2, 2020
    Assignee: Southwest Research Institute
    Inventors: Craig E. DeForest, Glenn T. Laurent, Jedediah H. Diller
  • Patent number: 10673475
    Abstract: The disclosure provides a transmitter of a communication system using hybrid digital/analog beamforming and configured to perform digital pre-distortion (DPD). In an exemplary embodiment in accordance with the disclosure, the transmitter may generate a plurality of scrambling sequences. The transmitter may comprise a plurality of combining modules to receive a combined feedback signal. The transmitter may use the plurality of scrambling sequences to recover the signals output by the antenna arrays from the combined feedback signal. Thus, the transmitter may perform DPD for each antenna array.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: June 2, 2020
    Assignee: Industrial Technology Research Institute
    Inventors: Wei-Cheng Zhuo, Wei-Min Lai, Jia-Ming Chen, Jen-Yuan Hsu
  • Patent number: 10669644
    Abstract: Disclosed herein are methods for electroplating which employ seed layer detection. Such methods may operate by selecting a wafer, illuminating one or more points within an interior region of the wafer surface, measuring a first set of one or more in-process color signals from the one or more points within the interior region, illuminating one or more points within an edge region of the wafer surface, measuring a second set of one or more in-process color signals from the one or more points within the edge region, each color signal having one or more color components, calculating a metric indicative of a difference between the color signals in the first and second sets of in-process color signals, determining whether an acceptable seed layer is present on the wafer based on whether the metric is within a predetermined range, and repeating the foregoing for one or more additional wafers.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: June 2, 2020
    Assignee: Lam Research Corporation
    Inventors: Daniel Mark Dinneen, Steven T. Mayer
  • Patent number: 10673935
    Abstract: A cloud service broker apparatus and method thereof are provided. The cloud service broker apparatus includes a controller configured to provide a brokerage service between a plurality of cloud service providers and a cloud service user by dividing a cloud service requested by the cloud service user into a plurality of cloud service segments and distributing each of the cloud service segments to each of the clouds.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: June 2, 2020
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Seok Ho Son, Dong Jae Kang, Jin Mee Kim, Hyun Joo Bae, Ji Hyun Lee
  • Patent number: 10669768
    Abstract: A system includes a door, an external electrical connection electrically coupled to a charge store, an opening assembly including a controller, an actuator, a gear, and an actuator arm. The actuator arm is mechanically coupled to the actuator and removably coupled to the door such that the actuator arm opens or closes the door upon actuation of the actuator and the external electrical connection electrically couples to a mobile robotic power delivery device that includes a battery to provide electrical power to the actuator and the controller.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: June 2, 2020
    Assignee: Toyota Research Institute, Inc.
    Inventors: Matthew Amacker, Jonathan Yao, Andrew Custer, Joe Taylor
  • Patent number: 10668151
    Abstract: This invention relates to antibody-albumin nanoparticle complexes comprising albumin, an antibody with binding specificity for a cancer antigen (e.g. panitumumab), and paclitaxel, wherein the nanoparticle complex has been pre-formed in vitro such that the nanoparticle complex has antigen-binding specificity (e.g. EGFR binding specificity), for the purpose of providing cancer (e.g. EGFR-related cancer) treatments in a subject in need thereof.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: June 2, 2020
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Svetomir N. Markovic, Wendy K. Nevala
  • Patent number: 10669633
    Abstract: Embodiments of the invention involve a technique and process for coating fine diameter, single strand wire of long continuous lengths with Parylene. The special fixture design and process allows for ultra thin (as thin as 0.2 micron), pore free, coatings. The advantages of this technology allow for wire products that offer minimal intrusion, superior routing and winding characteristics, and high heat and chemical resistance. The coating process can also be used for other types of material.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: June 2, 2020
    Assignee: AEROQUEST RESEARCH GROUP LLC
    Inventors: Thomas Lawrence, Nick Stahl, Jay Ahling
  • Patent number: 10669174
    Abstract: A water purification device is provided in the form of a hydrogel matrix containing immobilized nanoparticles that are directly synthesized in-situ in the hydrogel matrix. The hydrogel matrix is temperature sensitive, such that swelling draws in pollutants that are captured by the nanoparticles, while deswelling releases purified water. A related method of decontaminating the water supply contaminated with a target pollutant is also disclosed.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: June 2, 2020
    Assignee: THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
    Inventors: Dibakar Bhattacharyya, Li Xiao
  • Patent number: 10668069
    Abstract: A pharmaceutical composition including neptinib is provided. The composition includes neptinib or a pharmaceutically acceptable salt thereof, and an excipient at a low risk of compatibleness. Furthermore, the pharmaceutical composition of the present invention may also include pharmaceutically acceptable organic acid or inorganic acid as a stabilizer. The content of impurity A maintains a non-significant increase in the long-term and accelerated stability investigation for the pharmaceutical composition.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: June 2, 2020
    Assignee: SHENZHEN NEPTUNUS PHARMACEUTICAL RESEARCH INSITUTE CO., LTD
    Inventors: Jingan Yang, Zhiguo Wang, Jing Cui, Xiaorou Liu
  • Patent number: 10668122
    Abstract: The Toona sinensis extract of the present invention is prepared using supercritical fluid technique, wherein the method includes steps of: (a) drying the leaves of T. sinensis; (b) pulverizing the leaves as particles; and (c) extracting the particles with supercritical carbon dioxide to obtain the T. sinensis extract. This supercritical T. sinensis extract not only can decrease blood sugar level, but also promotes lipid degradation, inhibits the formation of huge lipid droplet and improves the metabolic symptoms. Accordingly, the T. sinensis extract further is able to be prepared as food supplement and pharmaceuticals.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: June 2, 2020
    Assignees: METAL INDUSTRIES RESEARCH & DEVELOPMENT CENTRE, KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: Pei-Jung Lien, Chuan-Chia Sun, Tzu-Chen Kuo, Sheng-Chung Yang, Yang-Chang Wu, Fang-Rong Chang, Tusty-Jiuan Hsieh, Yi-Hong Tsai, Ying-Chi Du