Patents Assigned to Research
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Patent number: 10449186Abstract: Halogenated phenylethynyl-substituted heterocycles that possess either an N-alkylamino or N,N-dialkylamino group attached to the heterocycle or halogenated phenylethynyl-substituted benzenes that a nitrogen-containing heterocycle attached to the benzene inhibit the proliferation cancer cells and are useful antineoplastic agents.Type: GrantFiled: May 10, 2018Date of Patent: October 22, 2019Assignee: University of Kentucky Research FoundationInventors: David S. Watt, Chunming Liu, Vitaliy M. Sviripa, Wen Zhang, Markos Leggas
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Patent number: 10455233Abstract: A method and a device for encoding/decoding an image are disclosed. The method for decoding an image comprises the steps of: decoding information on a quantization matrix; and restoring the quantization matrix on the basis of the information on the quantization matrix, wherein the information on the quantization matrix includes information indicating a DC value of the quantization matrix and/or information indicating differential values of quantization matrix coefficients.Type: GrantFiled: July 13, 2018Date of Patent: October 22, 2019Assignee: Electronics and Telecommunications Research InstituteInventors: Sung Chang Lim, Hui Yong Kim, Jin Ho Lee, Jin Soo Choi, Jin Woong Kim
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Patent number: 10454462Abstract: A Quadrature-In, Quadrature-Out (QIQO) clock divider divides by an odd divisor, such as three. An IQ input clock has in-phase and quadrature differential signals. Four stages of dynamic logic are arranged into a loop, with each stage output being one of four IQ output signals that have 90-degree phase separations. Each stage output drives the gates of a p-channel charging transistor and an n-channel discharging transistor of a next stage. Two p-channel charging logic transistors are in series between the next stage output and the p-channel charging transistor, and two n-channel evaluation transistors are in series between the next stage output and the n-channel discharging transistor. Different pairs of the four IQ input clock signals are applied to their gates. When the prior stage output is low, the stage output is charged. When the prior stage output is high, the stage output discharge timing is determined by the IQ signals.Type: GrantFiled: April 18, 2019Date of Patent: October 22, 2019Assignee: Hong Kong Applied Science and Technology Research Institute Company LimitedInventor: Tat Fu Chan
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Patent number: 10449227Abstract: The current invention pertains to a molecular conjugate comprising an antagonist of a cell surface receptor specific to a target cell and an immune effector, such as a T cell modulator, conjugated to the antagonist. The target cell can be a cell responsible for development of a disease in a subject, for example, a cancer cell. In certain embodiments, the immune effector is an immune effector protein or an immune effector fragment thereof. The current invention also pertains to a method of treating a disease in a subject, the method comprising administering to the subject a pharmaceutically effective amount of the molecular conjugates of the current invention to the subject. The methods of the current invention can be used to treat cancer, such as breast cancer, ovarian cancer, prostate cancer, lung cancer, pancreatic cancer, or melanoma.Type: GrantFiled: June 26, 2015Date of Patent: October 22, 2019Assignees: H. Lee Moffitt Cancer Center and Research Institute, Inc., University of South FloridaInventors: Mark McLaughlin, David L. Morse, Shari Pilon-Thomas, Scott Antonia
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Patent number: 10455604Abstract: A wireless system can include a plurality of directional antennas and a scheduler scheduling multiple links between the plurality of directional antennas. The scheduler can schedule the multiple links concurrently in the same time slot based on Regret Benefit Ratio (RBR). The RBR is a single indicator combining contention for one of the directional antennas and Quality of Service (QoS). The scheduler can introduce a contention graph for the directional antennas that capture a global knowledge of interference.Type: GrantFiled: January 9, 2018Date of Patent: October 22, 2019Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATEDInventors: Dapeng Oliver Wu, Yun Zhu, Jiade Li, Qiuyuan Huang
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Patent number: 10455677Abstract: Provided is an X-ray generator including a thermal electron emission type X-ray generator configured to generate a negative high voltage and a filament current, a field electron emission type X-ray generator including an anode electrode to be grounded, and configured to use the negative high voltage to bias the cathode electrode, and a field emission current control unit configured to convert the filament current to generate an output voltage to be provided to a gate electrode of the field electron emission type X-ray generator and convert the filament current to fix, to a specific level, a level of an emission current flowing through the cathode electrode.Type: GrantFiled: March 15, 2017Date of Patent: October 22, 2019Assignee: ELECTRONICS & TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Jun Tae Kang, Yoon-Ho Song, Jin-Woo Jeong
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Patent number: 10450490Abstract: The present invention relates to an article suitable to act as a thermal switch device, the article having a surface resistance of more than 105 ohms and formed from a polymer composition comprising from 50 to 99.9 wt % relative to the total weight of the polymer composition, of a polymer being selected from an amorphous polymer having a glass transition temperature Tg, a semi-crystalline polymer having a melting temperature Tm or a mixture thereof, and from 0.1 to 50 wt % relative to the total weight of the polymer composition, of a conductive material, wherein the surface resistance of the article is divided by at least 10, preferably by at least 100, when said article is submitted for a determined period of time of less than 5 minutes to a temperature of switch i) ranging from Tg+10° C. to Tg+250° C. if the polymer composition comprises an amorphous polymer, or ii) ranging from Tm?80° C. to Tm+250° C. if the polymer composition comprises a semi-crystalline polymer.Type: GrantFiled: March 11, 2016Date of Patent: October 22, 2019Assignee: TOTAL RESEARCH & TECHNOLOGY FELUYInventors: Olivier Lhost, Dimitri Rousseaux
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Patent number: 10454536Abstract: Disclosed herein are a method for transceiving a broadcast signal using a combination of multiple antenna schemes with layered division multiplexing and an apparatus for the method. A method for receiving a broadcast signal includes generating received signals based on signals that are received through multiple receiving antennas, estimating channels between the receiving antennas and transmitting antennas, restoring a core-layer signal corresponding to the received signals, and restoring an enhanced-layer signal based on a cancellation process, wherein the cancellation process corresponds to the core-layer signal and is separately performed for the individual receiving antennas.Type: GrantFiled: May 30, 2018Date of Patent: October 22, 2019Assignee: Electronics and Telecommunications Research InstituteInventors: Sung-Ik Park, Bo-Mi Lim, Sun-Hyoung Kwon, Heung-Mook Kim, Jae-Hyun Seo, Jae-Young Lee, Nam-Ho Hur, Hoi-Yoon Jung, David Gomez-Barquero, Eduardo Garro
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Patent number: 10450517Abstract: Systems and methods are provided for producing upgraded raffinate and extract products from lubricant boiling range feeds and/or other feeds having a boiling range of 400° F. (204° C.) to 1500° F. (816° C.) or more. The upgraded raffinate and/or extract products can have a reduced or minimized concentration of sulfur, nitrogen, metals, or a combination thereof. The reduced or minimized concentration of sulfur, nitrogen, and/or metals can be achieved by hydrotreating a suitable feed under hydrotreatment conditions corresponding to relatively low levels of feed conversion. Optionally, the feed can also dewaxed, such as by catalytic dewaxing or by solvent dewaxing. Because excessive aromatic saturation is not desired, the pressure for hydrotreatment (and optional dewaxing) can be 500 psig (˜3.4 MPa) to 1200 psig (˜8.2 MPa).Type: GrantFiled: May 19, 2017Date of Patent: October 22, 2019Assignee: ExxonMobil Research and Engineering CompanyInventors: Benjamin S. Umansky, Keith K. Aldous, James W. Gleeson, Edward J. Blok, Richard A. Demmin
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Patent number: 10449272Abstract: The present disclosure provides a hydrogel composition including: a hydrogel having a structure represented by Formula (I) or Formula (II) shown as follows: A-B-BOX-B-A, Formula (I); B-A-B-(BOX-BAB)n-BOX-B-A-B, Formula (II), wherein, A is a hydrophilic polyethylene glycol polymer, B is a hydrophobic polyester polymer, BOX is a bifunctional group monomer of 2,2?-Bis(2-oxazoline) for coupling di-block of A-B or tri-block of B-A-B, and n is an integer greater than or equal to 0; and an anti-adhesion additive, wherein the anti-adhesion additive comprises a carbohydrate, a nitrogen-containing cyclic compound, a polymer or a combination thereof.Type: GrantFiled: October 14, 2016Date of Patent: October 22, 2019Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Yu-Chi Wang, Hsin-Hsin Shen, Chin-Fu Chen, Meng-Yow Hsieh, Sen-Lu Chen, Yu-Bing Liou, Tsai-Yu Lin, Pei-Shan Li, Wei-Lin Yu
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Patent number: 10454523Abstract: A radio frequency signal generation device may include an optical comb generator configured to generate an optical comb signal including a plurality of first wavelength signals having different wavelengths; a pulse shaper configured to attenuate remaining wavelength signals excluding a plurality of second wavelength signals among the plurality of first wavelength signals; an optical-electronic converter configured to generate a radio frequency signal including a carrier frequency signal from the plurality of second wavelength signals outputted from the pulse shaper; and a pulse shaping controller configured to control the pulse shaper such that a carrier frequency of the carrier frequency signal varies according to a frequency hopping pattern.Type: GrantFiled: October 16, 2018Date of Patent: October 22, 2019Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Sungil Kim, Jung Min Park, Minje Song, Minhyup Song, Jae-Sik Sim, Joon Tae Ahn
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Patent number: 10454246Abstract: An optical pulse emitter includes a light emitting device having a first node coupled to an intermediate node via a first switch. The intermediate node is coupled to a supply voltage node via a second switch. A capacitor is coupled to the intermediate node. The first, second and third switches are controlled by a control circuit. During a first phase, the second switch is actuated to couple the capacitor to the supply voltage node. During a second phase, the second switch is deactuated and the first switch is actuated to at least partially discharge the capacitor through the light emitting device. During a third phase, discharge current from the capacitor bypasses around the light emitting device.Type: GrantFiled: February 24, 2016Date of Patent: October 22, 2019Assignees: STMicroelectronics (Grenoble 2) SAS, STMicroelectronics (Research & Development) LimitedInventors: Nicolas Moeneclaey, Shatabda Saha
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Patent number: 10448578Abstract: The invention relates to an end-effector device and automated selective thinning system. The system includes vision acquisition hardware, kinematic targeting and heuristic programming, a robotic arm, and a pomologically designed end-effector. The system is utilized to improve efficiency for the fruit-thinning process in a tree orchard, such as peach thinning By automating the mechanical process of fruit thinning, selective fruit-thinners can eliminate manual labor inputs and further enhance favorable blossom removal. Automation used in conjunction with a heuristic approach provides improvements to the system. The system may also be configured as a robotic arm or as a handheld system by including a battery and switching microcontroller with handle or wrist straps. Handheld thinning devices that are mechanical in nature may also be part of the system.Type: GrantFiled: July 21, 2015Date of Patent: October 22, 2019Assignee: The Penn State Research FoundationInventors: David Lyons, Paul Heinemann
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Patent number: 10452958Abstract: An image processing system includes a memory to store data indicative of benchmark feature vectors of benchmark images, an input interface to accept data indicative of a first feature vector of a first image and a second feature vector of a second image, and an output interface to render a similarity value between the first and the second images. The system includes a processor to determine the similarity using a first hyperplane separating the benchmark feature vectors from the first feature vector and a second hyperplane separating the benchmark feature vectors from the second feature vector. The processor determines a first normal vector to the first hyperplane as the difference between the first feature vector and the mean of the benchmark feature vectors. The processor determines an offset for the first hyperplane as the average of the maximum inner product of the benchmark feature vectors with the first normal vector and the inner product of the first feature vector with the first normal vector.Type: GrantFiled: October 6, 2017Date of Patent: October 22, 2019Assignee: Mitsubishi Electric Research Laboratories, Inc.Inventor: Michael Jones
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Patent number: 10452863Abstract: Systems and techniques, including a privacy service, facilitate selecting, defining, controlling, verifying, and auditing privacy-impacting behaviors of devices in alignment with the privacy behavior expectations of individuals and other entities. Techniques and systems are presented to facilitate controlling and verifying the privacy behaviors of privacy-impacting devices. Techniques and systems for defining and sharing individualized privacy behavior preferences are described. Techniques and systems are disclosed for privacy preference resolution protocols that allow for the automated or interactive resolution of conflicts that arise between individuals in multi-actor environments or ambiguous contexts. Accountability and audit mechanisms assist in verifying the control state of devices with respect to their privacy behavior preference inputs.Type: GrantFiled: October 3, 2018Date of Patent: October 22, 2019Assignee: Labyrinth Research LLCInventor: Kevin L Miller
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Patent number: 10453988Abstract: A method of creating cadmium telluride films is presented. The method demonstrates heterogeneous nucleation of CdTe directly on a substrate through sequential deposition of aqueous precursor solutions containing cadmium and telluride ions, respectively. The method can include (i) applying a cadmium precursor solution to the substrate to form a cadmium precursor film on the substrate, (ii) applying a telluride precursor solution to the cadmium precursor film. The telluride precursor solution includes Te2? in solution such that a CdTe film is adherently formed directly on the substrate.Type: GrantFiled: June 5, 2017Date of Patent: October 22, 2019Assignee: University of Utah Research FoundationInventors: Carina Hahn, Dennis Pruzan, Michael Scarpulla
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Patent number: 10455241Abstract: Disclosed are an image encoding/decoding method and device supporting a plurality of layers. The image decoding method supporting the plurality of layers comprises the steps of; receiving a bitstream comprising the plurality of layers; and decoding the bitstream so as to acquire maximum number information about sublayers with respect to each of the plurality of layers.Type: GrantFiled: September 20, 2018Date of Patent: October 22, 2019Assignee: Electronics and Telecommunications Research InstituteInventors: Jung Won Kang, Ha Hyun Lee, Jin Ho Lee, Jin Soo Choi, Jin Woong Kim
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Patent number: 10449200Abstract: Methods for treating tumors comprise contacting tumor cells expressing the vitamin D receptor with a vitamin D receptor ligand that inhibits homologous recombination in the tumor cells, and contacting the tumor cells with an amount of a Poly(ADP) Ribose Polymerase 1 (PARP-1) inhibitor. Inhibiting homologous recombination produces a synergistic therapeutic effect between the vitamin D receptor ligand and PARP-1 inhibitor, and may overcome PARP-1 resistance in killing tumor cells.Type: GrantFiled: December 20, 2017Date of Patent: October 22, 2019Assignee: The Research Institute of Fox Chase Cancer CenterInventors: Timothy J. Yen, Vikram Bhattacharjee
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Patent number: D863739Type: GrantFiled: August 21, 2018Date of Patent: October 22, 2019Assignee: Anatomic Research, Inc.Inventor: Frampton E. Ellis
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Patent number: D864340Type: GrantFiled: January 29, 2018Date of Patent: October 22, 2019Assignee: F-1 RESEARCH LLC—PATENT SERIESInventor: Dion Podgurny