Patents Assigned to Research
  • Publication number: 20130345231
    Abstract: The invention described herein pertains to anticancer therapeutic agents that exhibit preferential cytotoxicity to malignant cells that express a cancer specific isoform of proliferating cell nuclear antigen (caPCNA) compared to cytotoxicity to comparable non-malignant cells, pharmaceutical compositions comprising the agents, and their use in cancer therapy.
    Type: Application
    Filed: March 21, 2012
    Publication date: December 26, 2013
    Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
    Inventors: Robert J. Hickey, Linda H. Malkas
  • Publication number: 20130344563
    Abstract: A class of anionic oligomers and polymers that function for inhibition of nucleases, particularly RNase. Specific inhibitors include mixtures of oligomers of vinyl sulfate. Methods for inhibition or inactivation of one or more nucleases in vitro which comprises the step of contacting the one or more nucleases in a biological medium with one or more of the anionic oligomeric or polymeric inhibitors of this invention. Kits for carrying out a biological procedure, biological reaction and/or a biological assay containing one or more inhibitors of this invention. The use of oligomers and/or polymers of this invention as additives in buffers or reagents. The inhibitors of the invention can also be attached to surfaces to provide for removal of nucleases from media, solutions or other liquids in contact with the solid.
    Type: Application
    Filed: June 10, 2013
    Publication date: December 26, 2013
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Ronald T. RAINES, Bryan D. Smith, Matthew B. Soellner, David M. Lynn
  • Publication number: 20130340339
    Abstract: A gasifying apparatus including a variable gasifier and used as both a power generator and a combustion boiler and a method of driving the same are disclosed. A combustion boiler and a generator engine, driven with synthesis gas, are associated with a single gasifier, and the gasifying apparatus produces synthesis gas proper to a technical field of the gasifier by selectively applying an upflow gasifier and a downflow gasifier according to the technical field of the gasifier.
    Type: Application
    Filed: November 9, 2012
    Publication date: December 26, 2013
    Applicant: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Jae Goo LEE, Sang Jun YOON, Yong Ku KIM, Jae Ho KIM
  • Publication number: 20130341486
    Abstract: The present disclosure relates to an apparatus for obtaining 3D information using a photodetector array. The apparatus for obtaining 3D information includes: a light source unit configured to generate an optical signal of a predetermined wavelength band; a light transmission optical lens unit provided on a path of the optical signal and configured to emit the optical signal output from the light source unit in parallel or at a predetermined angle; an optical scanning unit configured to scan the light output from the light transmission optical lens unit to a surface of an object to be measured; a light reception optical lens unit configured to collect the light reflected from the surface of the object; and a photodetection unit configured to convert collected optical signals into respective electrical signals by arraying one or more photodetectors such that light reception portions thereof are collected at a center.
    Type: Application
    Filed: January 31, 2013
    Publication date: December 26, 2013
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: MyoungSook OH, Bongki MHEEN, Jae-Sik SIM, Kisoo KIM, Yun Jeong LEE, Yong-Hwan KWON, Eun Soo NAM
  • Publication number: 20130345374
    Abstract: A method for the copolymerization of ethylene and a C3+ olefin in a loop reactor and polymers formed therefrom are described herein. The method generally includes introducing an ethylene monomer, a C3+ olefin and a diluent carrier liquid into a loop reactor. A catalyst system can be supplied to said loop reactor. The diluent liquid, ethylene monomer, and C3+ olefin can be circulated through said loop reactor, while copolymerizing said ethylene and C3+ olefin in the presence of said catalyst system to produce a slurry. The slurry can be diverted into a settling leg, and sequentially discharged therefrom and withdrawn from said loop reactor. An ethylene monomer co-feed can be introduced into said loop reactor at spaced locations downstream of the ethylene and diluent. The ethylene co-feed can be introduced in an amount effective to reduce the variation in the ratio of ethylene and C3+ olefin.
    Type: Application
    Filed: June 14, 2013
    Publication date: December 26, 2013
    Applicant: TOTAL PETROCHEMICALS RESEARCH FELUY
    Inventors: Louis Fouarge, Eric Damme, Olivier Miserque, Daniel Siraux, Philippe Bodart, Andre Lewalle, Marc Van der Auwera, Frans Van den Brande, Giacomo Conti, Hugo Vandaele, Mark Verleysen, Carl Van Camp, Etienne Laurent, Philippe Marechal, Marc Moers, Leopold D'Hooghe, Marjan Sillis, Kai Hortman, Pascal Folie, Renaud Oreins
  • Publication number: 20130344112
    Abstract: Provided herein are methods of detecting and/or monitoring the presence or severity of an immune disorder in a subject, including detecting a frequency of a Th2a subset of CD4+ T cells in a biological sample of the subject. In some embodiments, the detecting includes: (a) detecting a frequency of CD4+ T cells in a biological sample of said subject; (b) detecting a frequency of a Th2a subset of the CD4+ T cells in the biological sample; and (c) comparing the frequency of the Th2a subset with the frequency of the CD4+ T cells.
    Type: Application
    Filed: August 23, 2013
    Publication date: December 26, 2013
    Applicant: Benaroya Research Institute
    Inventors: William W. Kwok, Erik Wombre
  • Publication number: 20130342153
    Abstract: Disclosed are a solar cell having a fan structure that provides a more pleasant life, convenience, and stability by forming, in a fan structure, a flexible colour solar cell applied with a carbon dioxide absorption material, and configuring the formed flexible colour solar cell through convergence of information technology, and an electronic application apparatus using the same. The electronic application apparatus using a solar cell as a power source includes: an application device body portion including a both side supporter fixed to ground, a transmitter including an antenna capable of transmitting power and data, and a data screen to thereby provide a predetermined service; and the solar cell provided in an upper end of the application device body portion, to colour using a predetermined wavelength of light, and to perform solar power generation using a remaining wavelength of light.
    Type: Application
    Filed: March 7, 2013
    Publication date: December 26, 2013
    Applicant: Electronics and Telecommunications Research Institute
    Inventor: Electronics and Telecommunications Research Institute
  • Publication number: 20130342403
    Abstract: A method and apparatus for testing antennas are provided. A given power level is transmitted on a first antenna of a device, via a processor. It is determined, at the processor, that the first antenna and a second antenna of the device are properly installed when received power at the second antenna is about greater than or equal to a threshold power level.
    Type: Application
    Filed: June 22, 2012
    Publication date: December 26, 2013
    Applicant: RESEARCH IN MOTION LIMITED
    Inventor: Marshall Joseph KATZ
  • Publication number: 20130345687
    Abstract: Disclosed herein are optical assemblies having thin, low profile shapes. These optical assemblies may be used with fiber coupled lasers and other light sources, including high power sources, to irradiate tissue at a wavelength suitable for inducing ablation or coagulation to a target depth, denaturation, thermal modification of a tissue, and/or preferential injury to a target tissue structure. Example optical assemblies can produce substantially uniform illumination patterns that are useful for treating superficial tissue, including the internal or luminal (e.g., esophageal) tissue. Some examples may have capability for cooling superficial tissue or skin, such as a detachable, reusable heat sink for active cooling without consumables, fluid pumps, or other cooling equipment.
    Type: Application
    Filed: August 13, 2013
    Publication date: December 26, 2013
    Applicant: Gradiant Research, LLC
    Inventors: Kathleen McMillan, Anurag Gupta, James Patrick McGuire, JR.
  • Publication number: 20130343420
    Abstract: Surface emitting laser structures that include a partially reflecting element disposed in the laser optical cavity are disclosed. A vertical external cavity surface emitting laser (VECSEL) structure includes a pump source configured to emit radiation at a pump wavelength, ?pump, an external out-coupling reflector, a distributed Bragg reflector (DBR,) and an active region arranged between the DBR and the out-coupling reflector. The active region is configured to emit radiation at a lasing wavelength, ?lase. The VECSEL structure also includes partially reflecting element (PRE) arranged between the gain element and the external out-coupling reflector. The PRE has reflectivity of between about 30% and about 70% for the radiation at the lasing wavelength and reflectivity of between about 30% and about 70% for the radiation at the pump wavelength.
    Type: Application
    Filed: March 22, 2012
    Publication date: December 26, 2013
    Applicant: PALO ALTO RESEARCH CENTER INCORPORATED
    Inventors: John E. Northrup, Thomas Wunderer, Noble M. Johnson
  • Publication number: 20130345117
    Abstract: The present invention provides a peptide-phospholipid conjugate of Formula 1: wherein: X is selected from the group consisting of —CR1R2—, —R3—, —O—, —S—, and S+(R3)—; Y is selected from the group consisting of a bond, alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, amino, ether, cycloamino, cycloether, aryl heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, to heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl; Z is a peptide comprising 1 to 50 amino acids; R1 and R2 each independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, amino, ether, cycloamino, cycloether, aryl, heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl; and R3 is selected from the group consisting of alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, amino, ether, cycloamino, cycloether,
    Type: Application
    Filed: January 19, 2012
    Publication date: December 26, 2013
    Applicant: Indiana University Research and Technology Corporation
    Inventors: Michael S. Van Nieuwenhze, William W. Turner, Joseph L. Witztum, Karsten Hartvigsen
  • Publication number: 20130342649
    Abstract: Disclosed are an apparatus and a method for transmitting a broadcasting service capable of signaling non-real-time 3D broadcasting content. An apparatus for transmitting a broadcasting service includes: a non-real-time (NRT) content encoder encoding stereoscopic image content including a reference image and an additional image to generate an NRT stream; an NRT signaling information encoder generating NRT signaling information including at least one of a service map table (SMT) and a non-real-time-information table (NRT-IT) that correspond to the content; and a multiplexer multiplexing the NRT stream and the NRT signaling information and transmitting the multiplexed NRT stream and NRT signaling information to a receiving apparatus. Therefore, content can be provided even when the reference image and the additional image are encoded into the single file format in the dual stream type.
    Type: Application
    Filed: March 9, 2012
    Publication date: December 26, 2013
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Hyun Jeong Yim, Kwang hee Jung, Hyoung Jin Kwon, Gwang Soon Lee, Kug Jin Yun, Won Sik Cheong, Nam Ho Hur
  • Publication number: 20130346433
    Abstract: Systems and methods for searching relationships between and among documents are disclosed. A user interface for presenting document objects and relationships between document objects located on a network is also disclosed. The document objects provided to the user may be determined based on document object references corresponding to the document objects. Document object information, relationship information, and contextual relationship information may also be provided to the user.
    Type: Application
    Filed: August 30, 2013
    Publication date: December 26, 2013
    Applicant: Bascom Research, LLC
    Inventors: Thomas Layne Bascom, Jason N. Harmon
  • Publication number: 20130344184
    Abstract: The subject invention pertains to materials and methods for the prevention and treatment of disease conditions associated with oxidative stress or a compromised reducing environment, including inflammatory bowel diseases such as ulcerative colitis. Another aspect of the subject invention concerns compositions formulated for administration as an enema. The subject invention also concerns compositions formulated for oral administration. Methods of the invention include administration of compounds or compositions of the invention. In one embodiment, compounds or compositions of the invention are rectally instilled in a patient. In another embodiment, compounds or compositions are orally administered.
    Type: Application
    Filed: June 28, 2013
    Publication date: December 26, 2013
    Applicant: THERAPEUTIC RESEARCH LLC
    Inventor: Jay PRAVDA
  • Publication number: 20130345454
    Abstract: The present invention relates to a synthetic method for the preparation of phytosteryl ferulate using ferulic acid and phytosterols (isolated from soybean oil deodorizer distillate) comprising of (a) acetylation of ferulic acid to ferulic acid acetate; (b) esterification of ferulic acid acetate with phytosterols to obtain phytosteryl ferulate acetate; (c) deprotection of phytosteryl ferulate acetate to phytosteryl ferulate. The phytosteryl ferulate was evaluated for hypocholesteremic activity in hamsters in comparison with that of natural oryzanol isolated from rice bran oil soap stock. This study confirmed that the phytosteryl ferulate significantly lowers the elevated cholesterol levels and also interferes with the absorption of cholesterol and the effect is comparable with that of natural oryzanol and is useful as nutraceutical/food supplement. Hence phytosteryl ferulate is a potential substitute for natural oryzanol for several applications.
    Type: Application
    Filed: February 25, 2010
    Publication date: December 26, 2013
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Bethala Lakshmi Anu Prabhavathi DEVI, Bhongiri YADAGIRI, Sanjit KANJILAL, Sistla RAMAKRISHNA, Kuncha MADHUSUDHANA, Prakash Vamanrao DlWAN, Rachapudi Badari Narayana PRASAD
  • Publication number: 20130345046
    Abstract: Disclosed are a bifunctional catalyst for simultaneously removing nitrogen oxide and particulate matters, capable of decomposing nitrogen monoxide and generating nitrogen dioxide through oxidation of nitrogen monoxide, a composite catalyst including the catalyst for simultaneously removing nitrogen oxide and particulate matters used for an apparatus to decrease exhaust gas of diesel vehicles, and a method for preparation thereof. The catalyst and the composite catalyst can be used in a device for reducing exhaust gas contaminants mounted on a diesel vehicle and an exhaust gas purification system comprising the device.
    Type: Application
    Filed: August 28, 2013
    Publication date: December 26, 2013
    Applicant: Korea Institute of Engergy Research
    Inventors: Jong-Soo Park, Kyung-Ran Hwang, Young-Jae Lee, Soon-Kwan Jeong, Dong-Kook Kim, Sung-Ho Cho, Chun-Boo Lee
  • Publication number: 20130345177
    Abstract: The present invention relates to the use of oleyl phosphocholine (C18:1-PC), or OlPC,for the treatment of mycosis, and especially for the treatment of mycosis such as mycosis caused by pathogens belonging to a genus selected from the group consisting of Candida, Aspergillus, Fusarium, Cryptococcus, Microsporum, Sporothrix, Trichophyton and Scedosporium, for example, Candida albicans, Candida parapsilosis, Candida glabrata, Candida krusei, Aspergillus fumigatus, Aspergillus niger, Aspergillus terreus, Fusarium solani, Scedosporium prolifacans, Cryptococcus neoformans, Microsporum canis, Sporothrix schenkii, Trichophyton rubrum, Trichophyton mentagrophytes, Aspergillus fumigatus, Fusarium oxysporum.
    Type: Application
    Filed: February 24, 2012
    Publication date: December 26, 2013
    Applicant: DAFRA PHARMA RESEARCH & DEVELOPMENT BVBA
    Inventor: Bruno Jansen
  • Publication number: 20130345383
    Abstract: Branched and hyperbranched oligomers and polymers that contain a cashew nutshell oil or liquid component are provided. The novel oligomers and polymers are suitable for use as an oil, lubricant, coating, adhesive, resin or composite.
    Type: Application
    Filed: January 6, 2012
    Publication date: December 26, 2013
    Applicant: NDSU RESEARCH FOUNDATION
    Inventors: Zhigang Chen, Ren Liu
  • Publication number: 20130345722
    Abstract: A method for repairing a perforation in a tympanic membrane comprising attaching a single patch to an undersurface of the tympanic membrane covering the perforation.
    Type: Application
    Filed: March 8, 2012
    Publication date: December 26, 2013
    Applicant: Mor Research Applications Ltd.
    Inventor: Ariel Margulis
  • Publication number: 20130346566
    Abstract: Provided are an apparatus and method of transmitting and receiving associated broadcasting contents based on a heterogeneous network. The transmission system generates a basic contents stream for basic contents configuring the broadcasting contents to transmit the basic contents stream to a terminal through a broadcasting network, generates an additional contents stream for additional contents associated with the basic contents to transmit the additional contents stream to the terminal through a communication network, and further transmits at least one of associated playing information on the basic contents and associated playing information on the additional contents to the terminal, and the reception terminal receives the basic contents stream, the additional contents stream, and the associated playing information and synchronize the basic contents and the additional contents with each other to play them, thereby playing the broadcasting contents in real time.
    Type: Application
    Filed: March 22, 2012
    Publication date: December 26, 2013
    Applicant: Electronics and Telecommunications Research Instit
    Inventors: Hyoung Jin Kwon, Kug Jin Yun, Gwang Soon Lee, Won Sik Cheong, Nam Ho Hur