Patents Assigned to Research
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Publication number: 20130345231Abstract: The invention described herein pertains to anticancer therapeutic agents that exhibit preferential cytotoxicity to malignant cells that express a cancer specific isoform of proliferating cell nuclear antigen (caPCNA) compared to cytotoxicity to comparable non-malignant cells, pharmaceutical compositions comprising the agents, and their use in cancer therapy.Type: ApplicationFiled: March 21, 2012Publication date: December 26, 2013Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATIONInventors: Robert J. Hickey, Linda H. Malkas
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Publication number: 20130344563Abstract: A class of anionic oligomers and polymers that function for inhibition of nucleases, particularly RNase. Specific inhibitors include mixtures of oligomers of vinyl sulfate. Methods for inhibition or inactivation of one or more nucleases in vitro which comprises the step of contacting the one or more nucleases in a biological medium with one or more of the anionic oligomeric or polymeric inhibitors of this invention. Kits for carrying out a biological procedure, biological reaction and/or a biological assay containing one or more inhibitors of this invention. The use of oligomers and/or polymers of this invention as additives in buffers or reagents. The inhibitors of the invention can also be attached to surfaces to provide for removal of nucleases from media, solutions or other liquids in contact with the solid.Type: ApplicationFiled: June 10, 2013Publication date: December 26, 2013Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Ronald T. RAINES, Bryan D. Smith, Matthew B. Soellner, David M. Lynn
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Publication number: 20130340339Abstract: A gasifying apparatus including a variable gasifier and used as both a power generator and a combustion boiler and a method of driving the same are disclosed. A combustion boiler and a generator engine, driven with synthesis gas, are associated with a single gasifier, and the gasifying apparatus produces synthesis gas proper to a technical field of the gasifier by selectively applying an upflow gasifier and a downflow gasifier according to the technical field of the gasifier.Type: ApplicationFiled: November 9, 2012Publication date: December 26, 2013Applicant: KOREA INSTITUTE OF ENERGY RESEARCHInventors: Jae Goo LEE, Sang Jun YOON, Yong Ku KIM, Jae Ho KIM
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Publication number: 20130341486Abstract: The present disclosure relates to an apparatus for obtaining 3D information using a photodetector array. The apparatus for obtaining 3D information includes: a light source unit configured to generate an optical signal of a predetermined wavelength band; a light transmission optical lens unit provided on a path of the optical signal and configured to emit the optical signal output from the light source unit in parallel or at a predetermined angle; an optical scanning unit configured to scan the light output from the light transmission optical lens unit to a surface of an object to be measured; a light reception optical lens unit configured to collect the light reflected from the surface of the object; and a photodetection unit configured to convert collected optical signals into respective electrical signals by arraying one or more photodetectors such that light reception portions thereof are collected at a center.Type: ApplicationFiled: January 31, 2013Publication date: December 26, 2013Applicant: Electronics and Telecommunications Research InstituteInventors: MyoungSook OH, Bongki MHEEN, Jae-Sik SIM, Kisoo KIM, Yun Jeong LEE, Yong-Hwan KWON, Eun Soo NAM
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Publication number: 20130345374Abstract: A method for the copolymerization of ethylene and a C3+ olefin in a loop reactor and polymers formed therefrom are described herein. The method generally includes introducing an ethylene monomer, a C3+ olefin and a diluent carrier liquid into a loop reactor. A catalyst system can be supplied to said loop reactor. The diluent liquid, ethylene monomer, and C3+ olefin can be circulated through said loop reactor, while copolymerizing said ethylene and C3+ olefin in the presence of said catalyst system to produce a slurry. The slurry can be diverted into a settling leg, and sequentially discharged therefrom and withdrawn from said loop reactor. An ethylene monomer co-feed can be introduced into said loop reactor at spaced locations downstream of the ethylene and diluent. The ethylene co-feed can be introduced in an amount effective to reduce the variation in the ratio of ethylene and C3+ olefin.Type: ApplicationFiled: June 14, 2013Publication date: December 26, 2013Applicant: TOTAL PETROCHEMICALS RESEARCH FELUYInventors: Louis Fouarge, Eric Damme, Olivier Miserque, Daniel Siraux, Philippe Bodart, Andre Lewalle, Marc Van der Auwera, Frans Van den Brande, Giacomo Conti, Hugo Vandaele, Mark Verleysen, Carl Van Camp, Etienne Laurent, Philippe Marechal, Marc Moers, Leopold D'Hooghe, Marjan Sillis, Kai Hortman, Pascal Folie, Renaud Oreins
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Publication number: 20130344112Abstract: Provided herein are methods of detecting and/or monitoring the presence or severity of an immune disorder in a subject, including detecting a frequency of a Th2a subset of CD4+ T cells in a biological sample of the subject. In some embodiments, the detecting includes: (a) detecting a frequency of CD4+ T cells in a biological sample of said subject; (b) detecting a frequency of a Th2a subset of the CD4+ T cells in the biological sample; and (c) comparing the frequency of the Th2a subset with the frequency of the CD4+ T cells.Type: ApplicationFiled: August 23, 2013Publication date: December 26, 2013Applicant: Benaroya Research InstituteInventors: William W. Kwok, Erik Wombre
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Publication number: 20130342153Abstract: Disclosed are a solar cell having a fan structure that provides a more pleasant life, convenience, and stability by forming, in a fan structure, a flexible colour solar cell applied with a carbon dioxide absorption material, and configuring the formed flexible colour solar cell through convergence of information technology, and an electronic application apparatus using the same. The electronic application apparatus using a solar cell as a power source includes: an application device body portion including a both side supporter fixed to ground, a transmitter including an antenna capable of transmitting power and data, and a data screen to thereby provide a predetermined service; and the solar cell provided in an upper end of the application device body portion, to colour using a predetermined wavelength of light, and to perform solar power generation using a remaining wavelength of light.Type: ApplicationFiled: March 7, 2013Publication date: December 26, 2013Applicant: Electronics and Telecommunications Research InstituteInventor: Electronics and Telecommunications Research Institute
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Publication number: 20130342403Abstract: A method and apparatus for testing antennas are provided. A given power level is transmitted on a first antenna of a device, via a processor. It is determined, at the processor, that the first antenna and a second antenna of the device are properly installed when received power at the second antenna is about greater than or equal to a threshold power level.Type: ApplicationFiled: June 22, 2012Publication date: December 26, 2013Applicant: RESEARCH IN MOTION LIMITEDInventor: Marshall Joseph KATZ
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Publication number: 20130345687Abstract: Disclosed herein are optical assemblies having thin, low profile shapes. These optical assemblies may be used with fiber coupled lasers and other light sources, including high power sources, to irradiate tissue at a wavelength suitable for inducing ablation or coagulation to a target depth, denaturation, thermal modification of a tissue, and/or preferential injury to a target tissue structure. Example optical assemblies can produce substantially uniform illumination patterns that are useful for treating superficial tissue, including the internal or luminal (e.g., esophageal) tissue. Some examples may have capability for cooling superficial tissue or skin, such as a detachable, reusable heat sink for active cooling without consumables, fluid pumps, or other cooling equipment.Type: ApplicationFiled: August 13, 2013Publication date: December 26, 2013Applicant: Gradiant Research, LLCInventors: Kathleen McMillan, Anurag Gupta, James Patrick McGuire, JR.
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Publication number: 20130343420Abstract: Surface emitting laser structures that include a partially reflecting element disposed in the laser optical cavity are disclosed. A vertical external cavity surface emitting laser (VECSEL) structure includes a pump source configured to emit radiation at a pump wavelength, ?pump, an external out-coupling reflector, a distributed Bragg reflector (DBR,) and an active region arranged between the DBR and the out-coupling reflector. The active region is configured to emit radiation at a lasing wavelength, ?lase. The VECSEL structure also includes partially reflecting element (PRE) arranged between the gain element and the external out-coupling reflector. The PRE has reflectivity of between about 30% and about 70% for the radiation at the lasing wavelength and reflectivity of between about 30% and about 70% for the radiation at the pump wavelength.Type: ApplicationFiled: March 22, 2012Publication date: December 26, 2013Applicant: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: John E. Northrup, Thomas Wunderer, Noble M. Johnson
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Publication number: 20130345117Abstract: The present invention provides a peptide-phospholipid conjugate of Formula 1: wherein: X is selected from the group consisting of —CR1R2—, —R3—, —O—, —S—, and S+(R3)—; Y is selected from the group consisting of a bond, alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, amino, ether, cycloamino, cycloether, aryl heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, to heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl; Z is a peptide comprising 1 to 50 amino acids; R1 and R2 each independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, amino, ether, cycloamino, cycloether, aryl, heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl; and R3 is selected from the group consisting of alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, amino, ether, cycloamino, cycloether,Type: ApplicationFiled: January 19, 2012Publication date: December 26, 2013Applicant: Indiana University Research and Technology CorporationInventors: Michael S. Van Nieuwenhze, William W. Turner, Joseph L. Witztum, Karsten Hartvigsen
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Publication number: 20130342649Abstract: Disclosed are an apparatus and a method for transmitting a broadcasting service capable of signaling non-real-time 3D broadcasting content. An apparatus for transmitting a broadcasting service includes: a non-real-time (NRT) content encoder encoding stereoscopic image content including a reference image and an additional image to generate an NRT stream; an NRT signaling information encoder generating NRT signaling information including at least one of a service map table (SMT) and a non-real-time-information table (NRT-IT) that correspond to the content; and a multiplexer multiplexing the NRT stream and the NRT signaling information and transmitting the multiplexed NRT stream and NRT signaling information to a receiving apparatus. Therefore, content can be provided even when the reference image and the additional image are encoded into the single file format in the dual stream type.Type: ApplicationFiled: March 9, 2012Publication date: December 26, 2013Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Hyun Jeong Yim, Kwang hee Jung, Hyoung Jin Kwon, Gwang Soon Lee, Kug Jin Yun, Won Sik Cheong, Nam Ho Hur
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Publication number: 20130346433Abstract: Systems and methods for searching relationships between and among documents are disclosed. A user interface for presenting document objects and relationships between document objects located on a network is also disclosed. The document objects provided to the user may be determined based on document object references corresponding to the document objects. Document object information, relationship information, and contextual relationship information may also be provided to the user.Type: ApplicationFiled: August 30, 2013Publication date: December 26, 2013Applicant: Bascom Research, LLCInventors: Thomas Layne Bascom, Jason N. Harmon
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Publication number: 20130344184Abstract: The subject invention pertains to materials and methods for the prevention and treatment of disease conditions associated with oxidative stress or a compromised reducing environment, including inflammatory bowel diseases such as ulcerative colitis. Another aspect of the subject invention concerns compositions formulated for administration as an enema. The subject invention also concerns compositions formulated for oral administration. Methods of the invention include administration of compounds or compositions of the invention. In one embodiment, compounds or compositions of the invention are rectally instilled in a patient. In another embodiment, compounds or compositions are orally administered.Type: ApplicationFiled: June 28, 2013Publication date: December 26, 2013Applicant: THERAPEUTIC RESEARCH LLCInventor: Jay PRAVDA
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Publication number: 20130345454Abstract: The present invention relates to a synthetic method for the preparation of phytosteryl ferulate using ferulic acid and phytosterols (isolated from soybean oil deodorizer distillate) comprising of (a) acetylation of ferulic acid to ferulic acid acetate; (b) esterification of ferulic acid acetate with phytosterols to obtain phytosteryl ferulate acetate; (c) deprotection of phytosteryl ferulate acetate to phytosteryl ferulate. The phytosteryl ferulate was evaluated for hypocholesteremic activity in hamsters in comparison with that of natural oryzanol isolated from rice bran oil soap stock. This study confirmed that the phytosteryl ferulate significantly lowers the elevated cholesterol levels and also interferes with the absorption of cholesterol and the effect is comparable with that of natural oryzanol and is useful as nutraceutical/food supplement. Hence phytosteryl ferulate is a potential substitute for natural oryzanol for several applications.Type: ApplicationFiled: February 25, 2010Publication date: December 26, 2013Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Bethala Lakshmi Anu Prabhavathi DEVI, Bhongiri YADAGIRI, Sanjit KANJILAL, Sistla RAMAKRISHNA, Kuncha MADHUSUDHANA, Prakash Vamanrao DlWAN, Rachapudi Badari Narayana PRASAD
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Publication number: 20130345046Abstract: Disclosed are a bifunctional catalyst for simultaneously removing nitrogen oxide and particulate matters, capable of decomposing nitrogen monoxide and generating nitrogen dioxide through oxidation of nitrogen monoxide, a composite catalyst including the catalyst for simultaneously removing nitrogen oxide and particulate matters used for an apparatus to decrease exhaust gas of diesel vehicles, and a method for preparation thereof. The catalyst and the composite catalyst can be used in a device for reducing exhaust gas contaminants mounted on a diesel vehicle and an exhaust gas purification system comprising the device.Type: ApplicationFiled: August 28, 2013Publication date: December 26, 2013Applicant: Korea Institute of Engergy ResearchInventors: Jong-Soo Park, Kyung-Ran Hwang, Young-Jae Lee, Soon-Kwan Jeong, Dong-Kook Kim, Sung-Ho Cho, Chun-Boo Lee
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Publication number: 20130345177Abstract: The present invention relates to the use of oleyl phosphocholine (C18:1-PC), or OlPC,for the treatment of mycosis, and especially for the treatment of mycosis such as mycosis caused by pathogens belonging to a genus selected from the group consisting of Candida, Aspergillus, Fusarium, Cryptococcus, Microsporum, Sporothrix, Trichophyton and Scedosporium, for example, Candida albicans, Candida parapsilosis, Candida glabrata, Candida krusei, Aspergillus fumigatus, Aspergillus niger, Aspergillus terreus, Fusarium solani, Scedosporium prolifacans, Cryptococcus neoformans, Microsporum canis, Sporothrix schenkii, Trichophyton rubrum, Trichophyton mentagrophytes, Aspergillus fumigatus, Fusarium oxysporum.Type: ApplicationFiled: February 24, 2012Publication date: December 26, 2013Applicant: DAFRA PHARMA RESEARCH & DEVELOPMENT BVBAInventor: Bruno Jansen
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Publication number: 20130345383Abstract: Branched and hyperbranched oligomers and polymers that contain a cashew nutshell oil or liquid component are provided. The novel oligomers and polymers are suitable for use as an oil, lubricant, coating, adhesive, resin or composite.Type: ApplicationFiled: January 6, 2012Publication date: December 26, 2013Applicant: NDSU RESEARCH FOUNDATIONInventors: Zhigang Chen, Ren Liu
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Publication number: 20130345722Abstract: A method for repairing a perforation in a tympanic membrane comprising attaching a single patch to an undersurface of the tympanic membrane covering the perforation.Type: ApplicationFiled: March 8, 2012Publication date: December 26, 2013Applicant: Mor Research Applications Ltd.Inventor: Ariel Margulis
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Publication number: 20130346566Abstract: Provided are an apparatus and method of transmitting and receiving associated broadcasting contents based on a heterogeneous network. The transmission system generates a basic contents stream for basic contents configuring the broadcasting contents to transmit the basic contents stream to a terminal through a broadcasting network, generates an additional contents stream for additional contents associated with the basic contents to transmit the additional contents stream to the terminal through a communication network, and further transmits at least one of associated playing information on the basic contents and associated playing information on the additional contents to the terminal, and the reception terminal receives the basic contents stream, the additional contents stream, and the associated playing information and synchronize the basic contents and the additional contents with each other to play them, thereby playing the broadcasting contents in real time.Type: ApplicationFiled: March 22, 2012Publication date: December 26, 2013Applicant: Electronics and Telecommunications Research InstitInventors: Hyoung Jin Kwon, Kug Jin Yun, Gwang Soon Lee, Won Sik Cheong, Nam Ho Hur