Abstract: Hematopoietic stem/progenitor cells (HSPC) and/or non-T effector cells are genetically modified to express (i) an extracellular component including a ligand binding domain that binds a cellular marker preferentially expressed on an unwanted cell; and (ii) an intracellular component comprising an effector domain. Among other uses, the modified cells can be administered to patients to target unwanted cancer cells without the need for immunological matching before administration.

Abstract: A metabolic enzyme-induced micro-nano plastic particle biodegradation method and a product analysis method therefor are disclosed. The biodegradation method includes the following steps: step (1), cutting an appropriate quantity of plastic products into small pieces; step (2), placing the plastic products in a ball mill tank and milling the plastic products in vacuum in a ball mill; step (3), weighing and dispersing the milled plastic sample with water to prepare a dispersion with a concentration; step (4), mixing the micro-nano plastic dispersion with a metabolic enzyme solution, and placing the mixed solution in a vortex oscillator for mixing well; and step (5), incubating the mixed solution in a waterproof incubator. The present invention provides for the first time a method for biodegradation and metabolism of micro-nano plastics under mild conditions and under the induction of a metabolic enzyme, namely, glutathione S-transferase.

Abstract: Compounds and methods are provided for the treatment of neurological or mitochondrial diseases, including epilepsy. In some embodiments, the compounds are substituted 1,4-naphthoquinones.

Abstract: Disclosed herein are a multi-view video encoding/decoding method and apparatus, and a method for transmitting a bitstream generated by the multi-view video encoding method. The multi-view video encoding method according to the present disclosure may include generating first bitstreams for each of a plurality of quantization parameters (QPs) different from each other by encoding an atlas for a multi-view video in the quantization parameters; extracting second bitstreams for sub-regions in the atlas from the first bitstreams; and generating a third bitstream by merging, among the second bitstreams, second bitstreams with a predetermined bit rate.

Abstract: A method comprising: obtaining a plurality of data sets, each of the plurality of data sets being generated, at least in part, by using by a different one of a plurality of sensors, each of a plurality of sensors including a wearable sensor that is worn by a user or a sensor that is positioned at a same location as the user; combining the plurality of data sets to produce a fused data set; processing the fused data set to identify at least one of a performance of the user in completing a task, a cognitive load of the user, and/or one or more objects that are positioned at the same location as the user; and outputting an indication of a state of the user based on an outcome of the processing.

Abstract: A method for keypoint matching performed by a semantically aware keypoint matching model includes generating a semanticly segmented image from an image captured by a sensor of an agent, the semanticly segmented image associating a respective semantic label with each pixel of a group of pixels associated with the image. The method also includes generating a set of augmented keypoint descriptors by augmenting, for each keypoint of the set of keypoints associated with the image, a keypoint descriptor with semantic information associated with one or more pixels, of the semantically segmented image, corresponding to the keypoint. The method further includes controlling an action of the agent in accordance with identifying a target image having one or more first augmented keypoint descriptors that match one or more second augmented keypoint descriptors of the set of augmented keypoint descriptors.

Abstract: An assembly for driving movement of an elongate surgical tool, comprising: a plurality of adjacent pairs of driving wheels, each pair of driving wheels having a space therebetween such that spaces of the plurality of pairs of driving wheels are axially aligned to form a channel for the elongate surgical tool to extend through; wherein at least one pair of driving wheels out of the plurality of pairs is arranged to lie on a plane different than a plane on which at least one other pair of driving wheels lies.

Abstract: A method of a base station may comprise: mapping at least one port of the base station to each of a plurality of user equipments (UEs) to be overloaded; configuring overloading signatures for a code division multiplexing (CDM) scheme; mapping the overloading signatures with the plurality of UEs to be overloaded, respectively; transmitting a message including configuration information of the overloading signatures to the plurality of UEs; and transmitting, to the plurality of UEs, signals multiplexed by the CDM scheme using the overloading signatures.

Abstract: Disclosed are a phase shift method and a device performing same, the method comprising the steps of: shifting a phase of an input signal by a phase shifter, and up-converting, by a frequency quadrupler, a frequency of the input signal of which the phase has been shifted, by a multiplication coefficient (N). According to the phase shift method and the device performing same, it is possible to overcome a phase resolution decrease that occurs when passing through a frequency quadrupler in super high-frequency LO beamforming technology synchronized with a conventional frequency quadrupler.

Abstract: A method for detecting the content of active ingredients of a compound Sophorae flavescentis radix injection and the fingerprint spectrum thereof. The method comprises using high performance liquid chromatography to perform detection, wherein the high performance liquid chromatography is operated under the condition of a C18 chromatographic column, and active ingredients comprise matrine, oxymatrine, macrozamin, sophocarpine, oxysophocarpine, sophoridine, or/and piscidic acid. The present method is an improved method for performing detection on a compound Sophorae flavescentis radix injection, by means of same, seven ingredients in the compound Sophorae flavescentis radix injection can be simultaneously determined, and a chromatographic fingerprint spectrum can be constructed, thereby providing a technical method for quality control of a compound Sophorae flavescentis radix injection.

Abstract: The invention relates to the field of medicinal chemistry, and discloses a class of biphenyl derivatives with PD-1/PD-L1 inhibitory activity, and a preparation method and use thereof. The invention further discloses a composition containing the biphenyl derivatives with PD-1/PD-L1 inhibitory activity or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier, and applications of the composition in preparation of PD-1/PD-L1 inhibitors. The compounds of the invention are useful in the therapy used to treat tumors.

Abstract: The present invention relates to an antigen composition for preventing or treating viral infectious diseases, comprising, as an active ingredient, a multiple variant protein of a recombinant hemagglutinin monomeric protein in an influenza virus. In addition, the present invention relates to an antigen composition for preventing or treating viral infectious diseases, comprising a scaffold-based fusion protein. The antigen composition for preventing or treating viral infectious diseases, according to the present invention, has an outstanding preventive effect of inhibiting the proliferation and replication of viruses having various mutations, and is recyclable and safe by means of using a recombinant protein, and thus can be widely used in various industrial fields, such as the medicine and life science fields.

Abstract: An encoding method, a decoding method, an electronic device and a storage medium are disclosed. The encoding method includes: acquiring stored data in a storage system, and acquiring nodes corresponding to the stored data to obtain a number of the nodes; dividing the acquired stored data into a sequence of information vectors, and generating an information matrix according to the number of the nodes and a number of the sequence of information vectors; and calculating an encoded block according to each information vector and the information matrix to obtain a sequence of encoded blocks.

Abstract: A metal oxide semiconductor (MOS)-based power device includes a semiconductor region, drain and source electrodes, a gate electrode separated from the semiconductor region by SiO2, where the channel length (CHL) has a range of between about 0.6 ?m and about 0.5 ?m, the silicon dioxide has a corresponding thickness (tox) range of between about 5 nm to about 30 nm, where the CHL has a range of between about 0.5 ?m and about 0.4 ?m, the tox has a corresponding range of between about 5 nm to about 25 nm, where the CHL has a range of between about 0.4 ?m and about 0.3 ?m, the tox has a corresponding range of between about 5 nm to about 20 nm, where the CHL has a range of between about 0.3 ?m and about 0.2 ?m, the tox has a corresponding range of between about 5 nm to about 15 nm.

Abstract: Disclosed are a method and an apparatus for transmitting or receiving uplink feedback information in a communication system. An operation method of a terminal may comprise receiving downlink control information (DCI) from a base station, the DCI including resource allocation information of a physical downlink shared channel (PDSCH); receiving data #n from the base station through the PDSCH indicated by the DCI; generating a hybrid automatic repeat request (HARQ) codebook including an HARQ response bit #n for the data #n and an HARQ response bit #n-1 for data #n-1 received from the base station before the data #n; and transmitting the HARQ codebook to the base station. Therefore, the performance of the communication system can be improved.

Abstract: The invention relates to antibacterial compositions comprising micrococcin P1 and at least one additional antibacterial agent, which is preferably a bacteriocin or an antibiotic. The compositions may be used as an antibacterial, particularly for preventing or treating a bacterial infection.

Abstract: An image processing device includes a processor that executes a procedure. The procedure includes: generating a manipulated image by executing first manipulation processing on an input image so as to anonymize information contained in the input image; generating a reconstructed image by performing reconstruction processing on the manipulated image to reconstruct the information; and, based on a comparison between the input image and the reconstructed image, determining whether or not to execute second manipulation processing on the input image or on the manipulated image to anonymize the information, wherein the second manipulation processing is different from the first manipulation processing.

Abstract: Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.

Abstract: Provided is a time series anomaly detection method using a GRU-based model. The method includes inputting time series data from a predetermined second to 1 second before a target point in time into a stacked GRU, outputting an output of the stacked GRU after passing through a fully connected layer, adding data from the predetermined second before the target point in time to an output value that has passed through the fully connected layer via a skip connection, and learning the GRU-based model to obtain predicted data at the target time point through actual data at the target time point and mean square error (MSE) loss on the basis of the added data. A similarity calculation unit is additionally provided to the GRU-based model, and the similarity calculation unit receives the time series data, generates latent variables, calculates a sum of similarities, and reflects importance of the latent variables, thereby learning the GRU-based model.

Abstract: A method for providing a mixed reality combined physical space, performed by an electronic controller of a physical space, may comprise: receiving a signal for conversion from a traditional physical space to a mixed reality physical space; controlling an operation of an actuator coupled to a curtain or blind that suppresses reflection of light on front and wall surfaces of a physical space according to an input of the signal such that the curtain or blind is unfolded; and controlling an illumination of a lighting of the mixed reality physical space to lower or increase the illumination at a specific level interval or continuously, wherein a quality of mixed reality content provided to the mixed reality physical space is improved by controlling the illumination of the lighting.