Abstract: The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.
Type:
Grant
Filed:
December 20, 2011
Date of Patent:
January 22, 2013
Assignees:
University of Florida Resesarch Foundation, Inc., Smithsonian Institutution
Inventors:
Hendrik Luesch, Taori Kanchan, Valerie J. Paul
Abstract: A method and apparatus for measuring strain on a surface of a substrate utilizes a substrate surface coated with at least one coating layer. The coating layer provides both luminescence and photoelasticity. The coating layer is illuminated with excitation light, wherein longer wavelength light is emitted having a polarization dependent upon stress or strain in the coating. At least one characteristic of the emitted light is measured, and strain (if present) on the substrate is determined from the measured characteristic.
Type:
Grant
Filed:
April 4, 2003
Date of Patent:
September 13, 2005
Assignees:
Resesarch Foundation, Inc., Visteon Global Technologies, Inc.
Inventors:
James P. Hubner, Peter G. Ifju, Kirk S. Schanze, Shujun Jiang, Yao Liu, David A. Jenkins