Patents Assigned to RESOLUTION BIOSCIENCE, INC.
  • Methods for the detection of genomic copy changes in DNA samples
    Patent number: 12559799
    Abstract: The present invention includes compositions and methods useful for the detection of a mutational change, SNP, translocation, inversion, deletion, change in copy number, or other genetic variation within a sample of cellular genomic DNA or cell-free DNA (cfDNA). In some embodiments, the compositions and methods of the present invention provide an extremely high level of resolution that is particularly useful in detecting copy number variations in a small fraction of the total cfDNA from a biological sample (e.g., blood).
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: February 24, 2026
    Assignee: Resolution Bioscience, Inc.
    Inventors: Christopher Raymond, Lee Lim, Jennifer Hernandez
  • Methods for targeted genomic analysis
    Patent number: 11999949
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: June 4, 2024
    Assignee: Resolution Bioscience, Inc.
    Inventors: Christopher K. Raymond, Christopher D. Armour, Lee P. Lim
  • High efficiency construction of DNA libraries
    Patent number: 11339391
    Abstract: The invention provides a method for efficient DNA library construction and targeted genetic analyses of the libraries.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: May 24, 2022
    Assignee: Resolution Bioscience, Inc.
    Inventors: Christopher K. Raymond, Lee P. Lim
  • Methods for the detection of genomic copy changes in DNA samples
    Patent number: 11319594
    Abstract: The present invention includes compositions and methods useful for the detection of a mutational change, SNP, translocation, inversion, deletion, change in copy number, or other genetic variation within a sample of cellular genomic DNA or cell-free DNA (cfDNA). In some embodiments, the compositions and methods of the present invention provide an extremely high level of resolution that is particularly useful in detecting copy number variations in a small fraction of the total cfDNA from a biological sample (e.g., blood).
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: May 3, 2022
    Assignee: Resolution Bioscience, Inc.
    Inventors: Christopher Raymond, Lee Lim, Jennifer Hernandez
  • Methods for targeted genomic analysis
    Patent number: 10907149
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: February 2, 2021
    Assignee: Resolution Bioscience, Inc.
    Inventors: Christopher K. Raymond, Christopher D. Armour, Lee P. Lim
  • Methods for targeted genomic analysis
    Patent number: 9932576
    Abstract: The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific genomic loci in a single assay. The present invention further provide methods for the sensitive and specific detection of target gene sequences and gene expression profiles.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: April 3, 2018
    Assignee: RESOLUTION BIOSCIENCE, INC.
    Inventors: Christopher K. Raymond, Christopher D. Armour, Lee P. Lim