Patents Assigned to Resolvyx Pharmacuticals, Inc.
  • Analogues of lipid mediators derived from ?-3 PUFAs and methods of use
    Patent number: 7595341
    Abstract: The present invention is directed to compounds that are analogues of lipid mediators derived from a fish oil-derived fatty acid, eicosapentaenoic acid [C20:5 ?-3; EPA], but with a longer tissue half-life and enhanced bioactivity. These analogues may be used to treat inflammatory, angioproliferative, cardiovascular, thrombophlebotic, vascular, ocular, dermatologic, neurodegenerative, pulmonary, endocrine, reproductive, rheumatologic and gastrointestinal diseases.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: September 29, 2009
    Assignees: Resolvyx Pharmacuticals, Inc., The Brigham and Women's Hospital
    Inventors: Daniel W. Goodman, Michael R. Hanley, Stuart L. Bursten, Charles N. Serhan