Patents Assigned to Response Biomedical Corporation
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Patent number: 8404493Abstract: Methods for measuring the amount of two or more analytes of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve determining a ratio of a detected amount of a single analyte of interest, to the sum of a detected amount of each of the analytes of interest plus a detected amount of a control, wherein the amount of each analyte of interest is directly or inversely related to the ratio for each analyte of interest.Type: GrantFiled: June 4, 2009Date of Patent: March 26, 2013Assignee: Response Biomedical CorporationInventors: Whalley K. Fong, Paul C. Harris, Brian G. Richards
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Patent number: 8318420Abstract: Methods of increasing specific binding, decreasing non-specific binding, and reducing false-positive interaction in solid phase assays for influenza are disclosed. In the methods, the solid phase apparatus (lateral flow solid phase apparatus or capillary flow solid phase apparatus) is subjected to elevated heat subsequent to application of a test sample to the solid phase apparatus.Type: GrantFiled: July 12, 2010Date of Patent: November 27, 2012Assignee: Response Biomedical CorporationInventors: Whalley K. Fong, Paul C. Harris
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Patent number: 8192943Abstract: Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods comprise sandwich assays, and utilize an internal calibration reaction that closely mimics the reaction of test particles by the use of a two-step reaction.Type: GrantFiled: December 21, 2009Date of Patent: June 5, 2012Assignee: Response Biomedical CorporationInventors: Paul C. Harris, Whalley K. Fong, Lynn Cloney
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Publication number: 20110269115Abstract: Methods of increasing specific binding, decreasing non-specific binding, and reducing false-positive interaction in solid phase assays for influenza are disclosed. In the methods, the solid phase apparatus (lateral flow solid phase apparatus or capillary flow solid phase apparatus) is subjected to elevated heat subsequent to application of a test sample to the solid phase apparatus.Type: ApplicationFiled: July 12, 2010Publication date: November 3, 2011Applicant: Response Biomedical CorporationInventors: Whalley K. Fong, Paul C. Harris
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Patent number: 7875433Abstract: Methods for measuring the relative amount of two or more analytes of interest in a fluid sample, as well as kits useful in the methods, are disclosed. The methods involve assays that utilize a solid phase apparatus with a membrane having an application point and at least two sample capture zones having sample capture reagents; analyte binding particles or analyte coated particles; and assessment of a ratio of such particles arrested in capture zones, wherein the ratio is equal to, or inversely equal to, the relative amounts of the analytes of interest in the fluid sample.Type: GrantFiled: February 15, 2008Date of Patent: January 25, 2011Assignee: Response Biomedical CorporationInventor: Paul C. Harris
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Patent number: 7691595Abstract: Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve providing a solid phase apparatus comprising a membrane having an application point, a sample capture zone, and a control capture zone, where the sample capture region is between the application point and the control capture zone; and providing a sample collection apparatus comprising a population of analyte binding particles or a population of analyte coated particles. In the assays, a fluid sample is introduced into the sample collection apparatus, and the resultant mixture is applied to the application point of the membrane. The fluid allows transport components of the assay by capillary action to and through the sample capture zone and subsequently to and through the control capture zone. The amount of analyte in the fluid sample is related (e.g.Type: GrantFiled: November 21, 2006Date of Patent: April 6, 2010Assignee: Response Biomedical CorporationInventor: Whalley K. Fong
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Publication number: 20100047857Abstract: Methods for measuring the amount of two or more analytes of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve determining a ratio of a detected amount of a single analyte of interest, to the sum of a detected amount of each of the analytes of interest plus a detected amount of a control, wherein the amount of each analyte of interest is directly or inversely related to the ratio for each analyte of interest.Type: ApplicationFiled: June 4, 2009Publication date: February 25, 2010Applicant: Response Biomedical CorporationInventors: Whalley K. Fong, Paul C. Harris, Brian G. Richards
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Patent number: 7659086Abstract: Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods comprise sandwich assays, and utilize an internal calibration reaction that closely mimics the reaction of test particles by the use of a two-step reaction.Type: GrantFiled: May 22, 2007Date of Patent: February 9, 2010Assignee: Response Biomedical CorporationInventors: Paul C. Harris, Whalley K. Fong, Lynn Cloney
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Publication number: 20080240983Abstract: A modular reader system and method provides for testing a test sample and determining characteristics of the sample. A first test module is configured to perform a first reading on a test sample and produce data regarding the reading. A second test module is configured to perform a second reading of the test sample and produce data regarding the second reading. The first and second test modules are communicatively coupled to a control module. The control module collects the data produced by the first and second test modules and processes the data to determine characteristics of the test sample.Type: ApplicationFiled: March 19, 2008Publication date: October 2, 2008Applicant: Response Biomedical CorporationInventor: Paul C. Harris
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Publication number: 20080206889Abstract: Methods for measuring the relative amount of two or more analytes of interest in a fluid sample, as well as kits useful in the methods, are disclosed. The methods involve assays that utilize a solid phase apparatus with a membrane having an application point and at least two sample capture zones having sample capture reagents; analyte binding particles or analyte coated particles; and assessment of a ratio of such particles arrested in capture zones, wherein the ratio is equal to, or inversely equal to, the relative amounts of the analytes of interest in the fluid sample.Type: ApplicationFiled: February 15, 2008Publication date: August 28, 2008Applicant: Response Biomedical CorporationInventor: Paul C. Harris
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Patent number: 7175992Abstract: Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve providing a solid phase apparatus comprising a membrane having an application point, a sample capture zone, and a control capture zone, where the sample capture region is between the contact region and the control capture zone; and providing a sample collection apparatus comprising a population of analyte binding particles or a population of analyte coated particles. In the assays, a fluid sample is introduced into the sample collection apparatus, and the resultant mixture is applied to the application point of the membrane. The fluid allows transport components of the assay by capillary action to and through the sample capture zone and subsequently to and through the control capture zone. The amount of analyte in the fluid sample is related (e.g.Type: GrantFiled: June 3, 2002Date of Patent: February 13, 2007Assignee: Response Biomedical CorporationInventor: Whalley K. Fong
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Publication number: 20040171092Abstract: Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample are disclosed. The methods involve providing a membrane having an application point, a contact region comprising analyte-binding particles, a sample capture zone, and a control capture zone, where the contact region is between the application point and the sample capture zone, and the sample capture region is between the contact region and the control capture zone. In the assays, a fluid allows transport components of the assay by capillary action through the contact region, to and through the sample capture zone and subsequently to and through the control capture zone. In a “sandwich assay” embodiment, the amount of analyte in the fluid sample is related to a corrected analyte-binding particle amount, which can be determined, for example, as a ratio of the amount of analyte-binding particles in the sample capture zone and the amount of analyte-binding particles in the control capture zone.Type: ApplicationFiled: November 14, 2003Publication date: September 2, 2004Applicant: Response Biomedical CorporationInventors: Paul C. Harris, Brian G. Richards
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Publication number: 20030199004Abstract: Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample, and kits useful in the methods, are disclosed. The methods involve providing a solid phase apparatus comprising a membrane having an application point, a sample capture zone, and a control capture zone, where the sample capture region is between the contact region and the control capture zone; and providing a sample collection apparatus comprising a population of analyte binding particles or a population of analyte coated particles. In the assays, a fluid sample is introduced into the sample collection apparatus, and the resultant mixture is applied to the application point of the membrane. The fluid allows transport components of the assay by capillary action to and through the sample capture zone and subsequently to and through the control capture zone. The amount of analyte in the fluid sample is related (e.g.Type: ApplicationFiled: June 3, 2002Publication date: October 23, 2003Applicant: Response Biomedical CorporationInventor: Whalley K. Fong
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Publication number: 20030162236Abstract: Methods for quantitatively measuring the amount of an analyte of interest in a fluid sample are disclosed. The methods involve providing a membrane having an application point, a contact region comprising analyte-binding particles, a sample capture zone, and a control capture zone, where the contact region is between the application point and the sample capture zone, and the sample capture region is between the contact region and the control capture zone. In the assays, a fluid allows transport components of the assay by capillary action through the contact region, to and through the sample capture zone and subsequently to and through the control capture zone. In a “sandwich assay” embodiment, the amount of analyte in the fluid sample is related to a corrected analyte-binding particle amount, which can be determined, for example, as a ratio of the amount of analyte-binding particles in the sample capture zone and the amount of analyte-binding particles in the control capture zone.Type: ApplicationFiled: March 26, 2001Publication date: August 28, 2003Applicant: Response Biomedical CorporationInventors: Paul C. Harris, Brian G. Richards
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Patent number: D612503Type: GrantFiled: March 29, 2007Date of Patent: March 23, 2010Assignee: Response Biomedical CorporationInventors: Robert Johnston, David Kwan-Kit Orr
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Patent number: D612514Type: GrantFiled: March 29, 2007Date of Patent: March 23, 2010Assignee: Response Biomedical CorporationInventors: Robert Johnston, David Kwan-Kit Orr