Abstract: A device to change the temperature of a localized volume of material. One device includes at least one heat transfer mechanism having a conformable external surface for direct contact with a surface of the material. A working fluid is directed by input and output conduits to contact an internal surface of the heat transfer mechanism. A wall of the heat transfer mechanism exchanges heat between the working fluid and the material. Temperature of the working fluid may be regulated by a thermal control system disposed at a remote location. An optional temperature sensing element may monitor a local temperature of the heat transfer mechanism or otherwise infer a temperature of a portion of the material. Portions of certain devices may be deformed to a desired device shape.

Abstract: A heat transfer device particularly structured for application of thermal therapy from a contact surface to internal structures of a human ear. A device may be passive (pre-cooled), active (thermoelectrically active), or include elements of both. A device may be structured to apply thermal treatment from a contact surface of a contact cavity only to a localized posterior area relative to the circumference of an ear. A device may include both of a contact cavity and a bulk cavity, with heat transfer media disposed in each cavity. Typically, a bulk cavity holds at least twice the media volume contained in a contact cavity. The cavities may be disposed in fluid communication, or separated by a barrier to permit only thermal communication there-between. When a barrier between cavities is present, a device may include different heat transfer media in each cavity.