Patents Assigned to Reva Medical, Inc.
  • Patent number: 10329379
    Abstract: The present invention provides new classes of phenolic compounds derived from hydroxyacids and tyrosol or tyrosol analogs, useful as monomers for preparation of biocompatible polymers, and the biocompatible polymers prepared from these monomeric hydroxyacid-phenolic compounds, including novel biodegradable and/or bioresorbable polymers. These biocompatible polymers or polymer compositions with enhanced bioresorbabilty and processability are useful in a variety of medical applications, such as in medical devices and controlled-release therapeutic formulations. The invention also provides methods for preparing these monomeric hydroxyacid-phenolic compounds and biocompatible polymers.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: June 25, 2019
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, REVA MEDICAL, INC.
    Inventors: Durgadas Bolikal, Joachim B. Kohn, Lioubov Kabalnova
  • Patent number: 10143493
    Abstract: Various polymeric materials and delivery systems are described, along with systems and methods for using them for bone and tissue augmentation, such as for the stabilization and/or correction of spinal compression fractures.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: December 4, 2018
    Assignee: Reva Medical, Inc.
    Inventors: Moni Stein, Donald K. Brandom, Lioubov Kabalnova, Steve Howard, Robert F. Dennis
  • Patent number: 9782523
    Abstract: Side-chain crystallizable (SCC) polymers are useful in various medical applications. In certain applications, heavy atom containing side-chain crystallizable polymers (HACSCCP's) are particularly useful. An example of a HACSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer. In certain configurations, the heavy atoms are present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes an HACSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product. A polymeric material that includes a SCC polymer may also be fabricated into other medical devices, such as stents.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: October 10, 2017
    Assignee: Reva Medical, Inc.
    Inventors: Donald K. Brandom, James E. McGrath, Joan Zeltinger, Eric V. Schmid, Robert K. Schultz
  • Patent number: 9452068
    Abstract: An expandable slide and lock stent comprises a tubular member that can be expanded from a collapsed state to an expanded state. The tubular member can comprise a reversing helical backbone and at least one rail member extending from the helical backbone in a circumferential direction. The backbone can have at least one engagement element that can be configured to receive a rail member to form the tubular member. In some embodiments, the reversing helical backbone can comprise a plurality of discrete segments having a variable profile and/or wave form.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: September 27, 2016
    Assignee: REVA Medical, Inc.
    Inventors: Eric Schmid, Keith Weier, Keith A. Esser, Steven C. Howard, John Hobson, Craig Bonsignore
  • Patent number: 9408732
    Abstract: An expandable slide and lock stent comprises a tubular member that can be expanded from a collapsed state to an expanded state. The tubular member can comprise a reversing helical backbone and at least one rail member extending from the helical backbone in a circumferential direction. The backbone can have at least one engagement element that can be configured to receive a rail member to form the tubular member. In some embodiments, the reversing helical backbone can comprise a plurality of discrete segments having a variable profile and/or wave form. A plurality of regions of each backbone may have a recessed or “nesting” profile providing for a smaller overall stent profile in a compacted configuration, and improved stent retention as mounted on a balloon catheter.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: August 9, 2016
    Assignee: REVA Medical, Inc.
    Inventors: Keith Weier, Steven C. Howard
  • Patent number: 9402859
    Abstract: Various polymeric materials and delivery systems are described, along with systems and methods for using them for bone and tissue augmentation, such as for the stabilization and/or correction of spinal compression fractures.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: August 2, 2016
    Assignee: REVA Medical, Inc.
    Inventors: Moni Stein, Donald K. Brandom, Lioubov Kabalnova, Steve Howard, Robert F. Dennis
  • Patent number: 9314354
    Abstract: Expandable medical implants for maintaining support of a body lumen are disclosed. These implants comprise an axially-radially nested, diametrically expandable, moveable vascular device for enlarging an occluded portion of a vessel. The device can be configured to allow for motion such as translating and/or slide and lock. One advantage of the axially-radially nested stent is that it maintains the expanded size, without significant recoil.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: April 19, 2016
    Assignee: Reva Medical, Inc.
    Inventors: Andrew Morris, Jeffrey T. Sheriff, Keith Esser
  • Patent number: 9173751
    Abstract: The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: November 3, 2015
    Assignee: REVA MEDICAL, INC.
    Inventors: Eric V. Schmid, John D. Nguyen, Steven C. Howard, Orlando M. Padilla, Andrew Morris, Robert F. Eisele, Daniel Moore, Thomas R. Jackson, Joan Zeltinger
  • Patent number: 9149378
    Abstract: The inventions relate generally to expandable medical implants for maintaining support of a body lumen and, in particular, to an axially nested, diametrically expandable, slide and lock vascular device for enlarging an occluded portion of a vessel. The axially nested vascular device desirably achieves both competitive crossing profiles while maintaining other key features, such as, for example, radial strength and luminal patency. The collapsed profile can also be made very thin without compromising radial strength. Thus, the vascular device can advantageously be deployed in small and difficult to reach areas or vessels. The axial nesting substantially eliminates radial overlap between mating structural elements thereby desirably allowing for a low, uniform profile.
    Type: Grant
    Filed: August 18, 2008
    Date of Patent: October 6, 2015
    Assignee: REVA MEDICAL, INC.
    Inventors: Andrew Morris, Eric Schmid, Jeffrey Sheriff, Brandon Felkins
  • Patent number: 9066827
    Abstract: An expandable slide and lock stent is provided that comprises a plurality of radial elements interconnected to form a tubular member. Each radial element can comprise a helical backbone and at least one elongate member extending from the helical backbone in a circumferential direction. Each backbone can have at least one slot that can be configured to receive an elongate member of an adjacent radial element.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: June 30, 2015
    Assignee: REVA Medical, Inc.
    Inventors: Eric Schmid, Andrew Morris, Keith Weier, Craig Bonsignore, Keith Esser, Steven C. Howard, Joseph A. DiPari
  • Publication number: 20140277375
    Abstract: An expandable slide and lock stent comprises a tubular member that can be expanded from a collapsed state to an expanded state. The tubular member can comprise a reversing helical backbone and at least one rail member extending from the helical backbone in a circumferential direction. The backbone can have at least one engagement element that can be configured to receive a rail member to form the tubular member. In some embodiments, the reversing helical backbone can comprise a plurality of discrete segments having a variable profile and/or wave form. A plurality of regions of each backbone may have a recessed or “nesting” profile providing for a smaller overall stent profile in a compacted configuration, and improved stent retention as mounted on a balloon catheter.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Applicant: REVA Medical, Inc.
    Inventors: Keith Weier, Steven C. Howard
  • Patent number: 8702716
    Abstract: Various polymeric materials and delivery systems are described, along with systems and methods for using them for bone and tissue augmentation, such as for the stabilization and/or correction of spinal compression fractures.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: April 22, 2014
    Assignee: REVA Medical Inc.
    Inventors: Moni Stein, Don Brandom, Lioubov Kabalnova, Steve Howard, Robert F. Dennis
  • Patent number: 8703113
    Abstract: Side-chain crystallizable (SCC) polymers are useful in various medical applications. In certain applications, heavy atom containing side-chain crystallizable polymers (HACSCCP's) are particularly useful. An example of a HACSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer. In certain configurations, the heavy atoms are present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes an HACSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product. A polymeric material that includes a SCC polymer may also be fabricated into other medical devices, such as stents.
    Type: Grant
    Filed: January 18, 2006
    Date of Patent: April 22, 2014
    Assignee: REVA Medical Inc.
    Inventors: Donald K. Brandom, James E. McGrath, Joan Zeltinger, Eric V. Schmid, Robert K. Schultz
  • Publication number: 20140094897
    Abstract: An expandable slide and lock stent is provided that comprises a plurality of radial elements interconnected to form a tubular member. Each radial element can comprise a helical backbone and at least one elongate member extending from the helical backbone in a circumferential direction. Each backbone can have at least one slot that can be configured to receive an elongate member of an adjacent radial element.
    Type: Application
    Filed: September 4, 2013
    Publication date: April 3, 2014
    Applicant: REVA Medical, Inc.
    Inventors: Eric Schmid, Andrew Morris, Keith Weier, Craig Bonsignore, Keith Esser, Steven C. Howard, Josepth A. DiPari
  • Publication number: 20140025159
    Abstract: Expandable medical implants for maintaining support of a body lumen are disclosed. These implants comprise an axially-radially nested, diametrically expandable, moveable vascular device for enlarging an occluded portion of a vessel. The device can be configured to allow for motion such as translating and/or slide and lock. One advantage of the axially-radially nested stent is that it maintains the expanded size, without significant recoil.
    Type: Application
    Filed: May 10, 2013
    Publication date: January 23, 2014
    Applicant: Reva Medical, Inc.
    Inventors: Andrew Morris, Jeffrey T. Sheriff, Keith Esser
  • Patent number: 8617235
    Abstract: The invention relates generally to expandable medical implants for maintaining support of a body lumen and, in particular, to an axially nested, diametrically expandable, slide and lock vascular device for enlarging an occluded portion of a vessel. The axially nested vascular device desirably achieves both competitive crossing profiles while maintaining other key features, such as, for example, radial strength and luminal patency. The collapsed profile can also be made very thin without compromising radial strength. Thus, the vascular device can advantageously be deployed in small and difficult to reach areas or vessels. The axial nesting substantially eliminates radial overlap between mating structural elements thereby desirably allowing for a low, uniform profile.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: December 31, 2013
    Assignee: REVA Medical, Inc.
    Inventors: Eric V. Schmid, John D. Nguyen, Orlando Padilla, Andrew Morris, Daniel Moore, Thomas R. Jackson
  • Patent number: 8545547
    Abstract: An expandable slide and lock stent is provided that comprises a plurality of radial elements interconnected to form a tubular member. Each radial element can comprise a helical backbone and at least one elongate member extending from the helical backbone in a circumferential direction. Each backbone can have at least one slot that can be configured to receive an elongate member of an adjacent radial element.
    Type: Grant
    Filed: May 23, 2011
    Date of Patent: October 1, 2013
    Assignee: Reva Medical Inc.
    Inventors: Eric Schmid, Andrew Morris, Keith Weier, Craig Bonsignore, Keith Esser, Steven C. Howard, Joseph A. DiPari
  • Publication number: 20130253631
    Abstract: The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.
    Type: Application
    Filed: September 13, 2012
    Publication date: September 26, 2013
    Applicant: REVA MEDICAL, INC.
    Inventors: Eric V. Schmid, John D. Nguyen, Steven C. Howard, Orlando M. Padilla, Andrew Morris, Robert F. Eisele, Joseph Anthony DiPari, David G. Matsuura, Philip J. Simpson, Walter D. Gillespie, Daniel Moore, Thomas R. Jackson, Joan Zeltinger, Keith Allen Esser, Donald K. Brandom
  • Patent number: 8540762
    Abstract: Expandable medical implants for maintaining support of a body lumen are disclosed. Some embodiments of these implants comprise a circumferentially nested, diametrically expandable, moveable vascular device for enlarging an occluded portion of a vessel. The device can be configured to allow for motion such as rotating, translating, and/or slide and lock.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: September 24, 2013
    Assignee: REVA Medical, Inc.
    Inventors: Eric Schmid, Andrew Morris, Orlando Padilla
  • Patent number: 8523936
    Abstract: An expandable slide and lock stent comprises a tubular member that can be expanded from a collapsed state to an expanded state. The tubular member can comprise a reversing helical backbone and at least one rail member extending from the helical backbone in a circumferential direction. The backbone can have at least one engagement element that can be configured to receive a rail member to form the tubular member. In some embodiments, the reversing helical backbone can comprise a plurality of discrete segments having a variable profile and/or wave form.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: September 3, 2013
    Assignee: REVA Medical, Inc.
    Inventors: Eric Schmid, Keith Weier, Keith A. Esser, Steven C. Howard, John Hobson, Craig Bonsignore