Abstract: The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds and the compounds used in such preparations.
Type:
Grant
Filed:
December 21, 2022
Date of Patent:
October 29, 2024
Assignee:
Revagenix, Inc.
Inventors:
Andrew Antony Calabrese, Timothy Robert Kane, Darin Hildebrandt, Michael Lopez, Nikolai Evdokimov, Frederick Cohen, Malken Bayrakdarian, Sanijia Xu, Samuel Desjardins, Olivier Soueidan
Abstract: The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds and the compounds used in such preparations.
Type:
Grant
Filed:
August 24, 2018
Date of Patent:
June 13, 2023
Assignee:
Revagenix, Inc.
Inventors:
Andrew Calabrese, Timothy Robert Kane, Darin Hildebrandt, Michael Lopez, Nikolai Evdokimov, Frederick Cohen, Malken Bayrakdarian, Sanjia Xu, Samuel Desjardins, Olivier Soueidan
Abstract: The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds and the compounds used in such preparations.
Type:
Application
Filed:
August 24, 2018
Publication date:
December 29, 2022
Applicant:
Revagenix, Inc.
Inventors:
Andrew CALABRESE, Timothy Robort KANE, Darin HILDEBRANDT, Michael LOPEZ, Nikolai EVDOKIMOV, Frederick COHEN, Malken BAYRAKDARIAN, Sanijia XU, Samuel DESJARDINS, Olivier SOUEIDAN
Abstract: Provided herein are aminoglycoside compounds, such as compounds of formula (I), (II), (III), (IV), (IVa), (V), (VI), (VIIa), or (VIIb) or pharmaceutically acceptable salts, solvates, stereoisomers, or tautomers of any of the foregoing, useful as therapeutic or prophylactic agents. Also provided herein are methods for their preparation. The compounds may be useful in treating a bacterial infection in a subject, for example a Gram-negative bacterial infection.
Type:
Grant
Filed:
August 24, 2018
Date of Patent:
August 16, 2022
Assignee:
REVAGENIX, INC.
Inventors:
Logan Andrews, Andrew Calabrese, Timothy Robert Kane, Ryan Cirz, Frederick Cohen, Michael Lopez, John Knox, Nikolai Evdokimov