Patents Assigned to Rexahn Corporation
  • Nucleoside derivatives and therapeutic use thereof
    Patent number: 7405214
    Abstract: The present invention relates to nucleoside derivatives represented by general formulas I and II, their synthetic methods and their pharmacologically acceptable salts thereof, and compositions containing such compounds. Methods for treating hyperproliferative disorders by administering the compounds are also included.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: July 29, 2008
    Assignee: Rexahn Corporation
    Inventors: Young Bok Lee, Chang Ho Ahn, Won Jun Choi, Lak Shin Jeong, Sang Kook Lee
  • Antisense oligonucleotides that inhibit expression of HIF-1
    Patent number: 7205283
    Abstract: New antisense oligonucleotide compounds, RX-0047 and RX-0149, inhibit expression of HIF-1 and also induce cytotoxicity in several cancer cell lines.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: April 17, 2007
    Assignee: Rexahn Corporation
    Inventors: Heejeong Yoon, Lingjun Mao, Young Bok Lee, Chang-Ho Ahn, Xiaoming Jiang
  • Use of antisense oligonucleotides to inhibit the expression of human Akt-1
    Patent number: 7122527
    Abstract: New antisense oligonucleotide compounds inhibit expression of Akt-1 and also induce cytotoxicity in several cancer cell lines.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: October 17, 2006
    Assignee: Rexahn Corporation
    Inventors: Heejeong Yoon, Lingjun Mao, Young Bok Lee, Chang Ho Ahn
  • Nucleoside derivatives and therapeutic uses therof
    Publication number: 20050222185
    Abstract: The present invention relates to nucleoside derivatives represented by general formulas I and II, their synthetic methods and their pharmacologically acceptable salts thereof, and compositions containing such compounds. Methods for treating hyperproliferative disorders by administering the compounds are also included.
    Type: Application
    Filed: April 1, 2005
    Publication date: October 6, 2005
    Applicant: Rexahn Corporation
    Inventors: Chang Ahn, Won Choi, Young Lee, Lak Jeong, Sang Lee